To be more clear: Failure can happen due to both internal and external forces. This advice enshrines internal power structures and ensures their systemic faults are permanent. It's not a seat at the table if you don't have a say.

[1] https://github.com/ryzendew/AffinityOnLinux

The brain definitely stores things, and retrieval and processing are key to the behaviour that comes out the other end, but whether it's "memory" like what this article tries to define, I'm not sure. The article makes it a point to talk about instances where /lack/ of a memory is a sign of the brain doing something different from an LLM, but the brain is pretty happy to "make up" a "memory", from all of my reading and understanding.

It's a statement that /feels/ true, because we can all look "inside" our heads and "see" memories and facts. But we may as well be re-constructing facts on the fly, just as re-construct reality itself to sense it.

What a terrible day to be literate and be able to read into the ugly belly of self-righteousness disguised as morality.

1. Stephen Hell has been theorizing about how to do super-res microscopy since the mid-90s, so the article saying it was sci-fi "20 years ago" is off by about 10 years.

2. Stephen Hell has recently given the world another new technique, MINFLUX, which seems to be his best gift to super-res researchers so far. :)

1. The size of Apple/Alphabet/Samsung makes it difficult to enter the market (see: factories having ridiculous MOQs for small-batch phone manufacturing), pushing everyone else out.

2. The size of the smartphone market makes it impossible to not have to deal with one of the above companies for certification, market penetrance or such. This makes them kingmakers. If a company somehow manages to become Facebook, Netflix, or Amazon, then the phone companies slide them a secret deal under the table. Everyone else gets a market-limiting set of terms that makes sure "tech" stays one of the "top" industries.

Combined, with no entry allowed, and with forces exerted outwards, we see broad social structures orienting /around/ how we use our phones, rather than the other way around, and that includes ad-monetized-absolutely-everything.

Phones and social media, today, are where TVs and broadcasts were in the 1950s/60s. Ubiquity and centralizing forces. If someone told us in the 1950s a TV manufacturer was exerting pressure on our forms of information distribution and was choosing which voices get a seat at the table, we'd rightly call that archaic and wonder why people would accept a technology provider as a market-shaping force. But today we accept it nonetheless. I refuse to believe the argument that the world's largest company can't figure out how to build a secure pipeline without making plenty of my decisions on my behalf...

I think figuring out the constraints one likes to work with can act as a great filter once someone knows what kind of success, goals, values and life they want to inhabit. Otherwise, it's as arbitrary as goal setting.

For me, I parroted other people's cool-sounding goals for a lot of my life, achieving varying degrees of success and happiness. Only in retrospect can I look at my favourite success and failure stories and consider which constraints, if I held them earlier, would have helped me narrow down to those favourite storylines from the get-go. Those constraints, I keep near and dear to my heart and attention in my daily life.

I don't think there's a way to set a meaningful constraint before practicing setting goals first. Walk before you run, etc. etc.

Genetic regulation can at best let us know _involvement_ of a gene, but nothing about why. Some examples of why a gene might be involved: it's a compensation mechanism (good!), it modulates the timing of the actual critical processes (discovery worthy but treatment path neutral), it is causative of a disease (treatment potential found) etc...

We don't need pipelines for faster scientific thinking ... especially if the result is experts will have to re-validate each finding. Most experts are anyway truly limited by access to models or access to materials. I certainly don't have a shortage of "good" ideas, and no machine will convince me they're wrong without doing the actual experiments. ;)

@OP: I'm wondering if more than just sorting, whether filtering could be added? I would want to find both highly rated books with high numbers of reviews.