<rss version="2.0" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Hacker News: Gluber</title><link>https://news.ycombinator.com/user?id=Gluber</link><description>Hacker News RSS</description><docs>https://hnrss.org/</docs><generator>hnrss v2.1.1</generator><lastBuildDate>Thu, 16 Jul 2026 00:37:07 +0000</lastBuildDate><atom:link href="https://hnrss.org/user?id=Gluber" rel="self" type="application/rss+xml"></atom:link><item><title><![CDATA[New comment by Gluber in "Sleep regularity is a stronger predictor of mortality risk than sleep duration (2023)"]]></title><description><![CDATA[
<p>In Austria a lot of times as second line ( after melatonin etc ) quetiapine is prescribed for its off label effects.</p>
]]></description><pubDate>Wed, 15 Jul 2026 16:45:37 +0000</pubDate><link>https://news.ycombinator.com/item?id=48923587</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=48923587</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48923587</guid></item><item><title><![CDATA[New comment by Gluber in "Is "colorectal cancer" rising in "young people"?"]]></title><description><![CDATA[
<p>The guidlines are where i live (Austria)
First Colo at 45, if nothing found -> Every 5 years. Once a poly is found and removed get one every 2-3 years.</p>
]]></description><pubDate>Tue, 26 May 2026 22:31:04 +0000</pubDate><link>https://news.ycombinator.com/item?id=48286882</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=48286882</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48286882</guid></item><item><title><![CDATA[New comment by Gluber in "You can't pay me to prompt"]]></title><description><![CDATA[
<p>My take on AI ( at least for coding ) is the same as for dynamic languages ( python,ruby etc )<p>1. Its a great tool to reduce boilerplate 
2. Its great for experimenting with ideas without the overhead that comes with starting a new non trivial project
3. Its great for one offs, demos or anything like that. 
4. It helps me to work on some personal side projects that would have never seen the light of day otherwise.<p>The downsides:<p>1. As with dynamic languages its a great tool for EXPERT engineers ( not that i am calling me one ) but is often used by Juniors/Entree Level engineers who do not understand the problem, can't tell it exactly what to do, and can't judge the result. And thus it leads to codebases riddled with issues that are hard to find and since they produce a lot of code are a huge liability.<p>"But look what i made" .... no... no you didn't you don't even understand why its doing something.</p>
]]></description><pubDate>Sat, 24 Jan 2026 13:55:18 +0000</pubDate><link>https://news.ycombinator.com/item?id=46743547</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=46743547</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=46743547</guid></item><item><title><![CDATA[New comment by Gluber in "XMLUI"]]></title><description><![CDATA[
<p>I agree with you that these things are important. However they are ( in implementation terms ) rather small issues, and determining i rather pay 4-8x more in development and maintenance costs just for this, while you can go the other way and make those features a bit hardware to implement seems like a not so good business case to me.<p>e.g we are using Avalonia. Of course everything is drawn in a scalable way, with responsive design etc... Accessibility is built in of course ( with integration with the relevant browser apis ) screenreaders work perfectly as do other accessibility features ) Its not the hap hazard way that flash did this  (before there were relevant standards for these features anyways ) 
Invoking a brower api / interop is easy, the difference is we do not need to compromise our productivity for small things.</p>
]]></description><pubDate>Sun, 20 Jul 2025 21:25:29 +0000</pubDate><link>https://news.ycombinator.com/item?id=44629430</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=44629430</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=44629430</guid></item><item><title><![CDATA[New comment by Gluber in "XMLUI"]]></title><description><![CDATA[
<p>The browser platform with HTML/CSS is fundamently legacy over legacy and broken for most application styles ( not general pages ), and incurs insane development costs for even simple things ( been there done that for close to 17 years )<p>The current best option IMO is: Open Full Browser window size canvas (with webgl, webgpu backend graphics ) and draw everyhing yourself ( meaning with something else than the browser layout engine, lots of options available, Flutter, Avalonia etc... ) and deploy with your favourite programming language through WASM.<p>In fact a next generation browser should bascially be this, with the legacy browser functionality implemented as a WASM module that draws to this single canvas... The browser would become small and much easiert to secure ( only input, audio and general WASI style apis missing and to secure )</p>
]]></description><pubDate>Sun, 20 Jul 2025 21:03:55 +0000</pubDate><link>https://news.ycombinator.com/item?id=44629291</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=44629291</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=44629291</guid></item><item><title><![CDATA[New comment by Gluber in "Ask HN: A friend has brain cancer: any bio hacks that worked?"]]></title><description><![CDATA[
<p>Did your friend get genetic sequencing done on his tumor. There are some recent promising results for braf mutated gbm</p>
]]></description><pubDate>Thu, 09 Jan 2025 21:46:42 +0000</pubDate><link>https://news.ycombinator.com/item?id=42650101</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=42650101</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=42650101</guid></item><item><title><![CDATA[New comment by Gluber in "Sisk – Lightweight .NET Web Framework"]]></title><description><![CDATA[
<p>Avalonia</p>
]]></description><pubDate>Sat, 31 Aug 2024 16:41:35 +0000</pubDate><link>https://news.ycombinator.com/item?id=41410027</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=41410027</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=41410027</guid></item><item><title><![CDATA[New comment by Gluber in "Sisk – Lightweight .NET Web Framework"]]></title><description><![CDATA[
<p>Last time i looked Kestrel already uses most of the techniques above ( sans an IOUring backend for Socket ) Almost all allocations are pooled, and zero copy as well. 
Header parsing is even done with System.Runtime.Intrinsics using SIMD where possible.<p>The higher level ASP.NET Core stack is also quite efficient and optimized.<p>BUT: as soon as you gove above the basic middleware pipeline its tends to get bloated and slow. ASP.NET COre MVC is particulary bad.<p>System.Text.Json is also quite nice, and often is allocation free.<p>We bascially just us the middleware pipeline and nothing else, and can get millions of requests per second on basic hardware.</p>
]]></description><pubDate>Sat, 31 Aug 2024 16:41:21 +0000</pubDate><link>https://news.ycombinator.com/item?id=41410024</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=41410024</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=41410024</guid></item><item><title><![CDATA[New comment by Gluber in "Sisk – Lightweight .NET Web Framework"]]></title><description><![CDATA[
<p>Isn't HttpListener still windows only ? I Remember the times we used it and it relied on http.sys on windows...<p>Or did they port it during NET/NET Core. As Kestrel has been the recommendation from NET Core 1.0 onwards.</p>
]]></description><pubDate>Sat, 31 Aug 2024 16:35:50 +0000</pubDate><link>https://news.ycombinator.com/item?id=41409974</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=41409974</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=41409974</guid></item><item><title><![CDATA[New comment by Gluber in "Sisk – Lightweight .NET Web Framework"]]></title><description><![CDATA[
<p>It is actually possible, to seperate those things, but it's tricky.
Our current product can run in several modes, one with a web ui and api and one without. If running without there is no trace of the ASP.NET Core Pipeline ( and Kestrel is also not running )<p>We're using ASP.NET Core Minimal APIS for both API and UI (if configured to run in that mode )</p>
]]></description><pubDate>Sat, 31 Aug 2024 15:00:40 +0000</pubDate><link>https://news.ycombinator.com/item?id=41409358</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=41409358</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=41409358</guid></item><item><title><![CDATA[New comment by Gluber in "Sisk – Lightweight .NET Web Framework"]]></title><description><![CDATA[
<p>Dammit you were first to ask that question :-) I also don't see the difference.</p>
]]></description><pubDate>Sat, 31 Aug 2024 14:44:55 +0000</pubDate><link>https://news.ycombinator.com/item?id=41409247</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=41409247</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=41409247</guid></item><item><title><![CDATA[New comment by Gluber in "Sisk – Lightweight .NET Web Framework"]]></title><description><![CDATA[
<p>Reading the docs and samples...<p>What are the advantages compared to e.g
ASP.NET Core Minimal Api ?<p>(or for example FastEndpoints) ?</p>
]]></description><pubDate>Sat, 31 Aug 2024 14:44:33 +0000</pubDate><link>https://news.ycombinator.com/item?id=41409243</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=41409243</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=41409243</guid></item><item><title><![CDATA[New comment by Gluber in "Supreme Court rules ex-presidents have immunity for official acts"]]></title><description><![CDATA[
<p>It's really weird to watch all that from the other side of the pond. 
In my country for example, all politicians have immunity but our parliament can revoke it for anyone using a majority ruling... ( having more than two political parties helps )</p>
]]></description><pubDate>Mon, 01 Jul 2024 20:45:29 +0000</pubDate><link>https://news.ycombinator.com/item?id=40850451</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=40850451</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=40850451</guid></item><item><title><![CDATA[New comment by Gluber in "The costs of microservices (2020)"]]></title><description><![CDATA[
<p>Every company i have advised jumped on the microservice bandwagon some time ago.... 
Here is what I tell them:<p>1. Microservices are a great tool... IF you have a genuine need for them
2. Decoupling in and on itself with services it not a goal
3. Developers who are bad at writing proper modular code in a monolithic setting will not magically write better code in a Microservice environment.. Rather it will get even worse since APIS ( be it GRPC, Restful or whatever ) are even harder to design
4. Most developers have NO clue about consistency or how to achieve certrain gurantees in a microservice setting ( Fun fact: My first question to developers in that area is: Define your notion of consistency, before be get to the fun stuff like RAFT or PAXOS)
5. You don't have the problems where microservices shine ( e.g banks with a few thounsands RPS ) 
6. Your communication overhead will dramatically increase 
7. Application A that does not genuinly need microservices will be much cheaper as a monolith with proper code seperation<p>Right now we have generation of developers and managers who don'T know any better, and just do what everybody else seems to be doing: Microservices and Scrum ... and then wonder why their costs explode.</p>
]]></description><pubDate>Mon, 30 Oct 2023 20:31:17 +0000</pubDate><link>https://news.ycombinator.com/item?id=38075347</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=38075347</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=38075347</guid></item><item><title><![CDATA[New comment by Gluber in "Hyperrealistic personalized AI Headshots"]]></title><description><![CDATA[
<p>There seems to be an outage right now, <a href="https://us-central1-photogenicai.cloudfunctions.net/api/inference" rel="nofollow">https://us-central1-photogenicai.cloudfunctions.net/api/infe...</a> returns status code 500</p>
]]></description><pubDate>Mon, 15 May 2023 10:20:53 +0000</pubDate><link>https://news.ycombinator.com/item?id=35945963</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=35945963</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=35945963</guid></item><item><title><![CDATA[Ask HN: Data Management for AI Training]]></title><description><![CDATA[
<p>I am currently in charge of deciding on the tech stack for a large scale AI project in the computer vision space.<p>Most things are settled, but we expect to collect a LOT of data that will be labeled and or auto labeled ( to the tune of 100 MIO video clips )<p>We will be training multiple models for different tasks from that data and we need a good system to organize it.<p>Does anybody have any tips experiences with that kind of thing. 
We can use any on premise or cloud solution....<p>Specifically we would need<p>* Data ingestion pipeline ( data will come from field personel ) 
* Data versioning
* Being able to define datasets that are a subset of the whole collected data
* Inexpensive storage ( e.g S3 or similar ) 
* Branching/Merging for maintaining production training data sets
* Metadata storage and query capabilities ... 
* User interface for less tech savy people ( e.g just a git like command line is fine for engineers but not for field personell who are not in IT )<p>I know of tools like https://dvc.org/ but a) they are just layers on top of git b) break appart on huge datasets without a folder hierarchy ( git tree objects just don't work for linear lists of items ) are only useable by IT personell, and require checking out at least a part of the dataset.<p>Our datasets would be 100.000.000 x 100 MB = 10 PB of raw data. Training data should be delivered to training nodes via network etc.. we just can't have a full checkout of that data...</p>
<hr>
<p>Comments URL: <a href="https://news.ycombinator.com/item?id=35763004">https://news.ycombinator.com/item?id=35763004</a></p>
<p>Points: 1</p>
<p># Comments: 3</p>
]]></description><pubDate>Sun, 30 Apr 2023 14:45:35 +0000</pubDate><link>https://news.ycombinator.com/item?id=35763004</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=35763004</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=35763004</guid></item><item><title><![CDATA[New comment by Gluber in "“Clean” code, horrible performance"]]></title><description><![CDATA[
<p>I agree but i think that mostly comes from Clean Code being kind of required reading for junior developers, that lack the experience to understand those concepts in context. No methodology is perfect, and there are always cases where one needs to break out of them, to know when to do that comes with experience.<p>For juniors which have no experience, any sane methodology is better than none, since otherwise you get even more of a mess.<p>That said, Clean code has some great advice, some mediocre advice and some frankly bad advice, but the authors point are largely irrelevant to 99 % of software engineering.</p>
]]></description><pubDate>Wed, 01 Mar 2023 00:40:58 +0000</pubDate><link>https://news.ycombinator.com/item?id=34977167</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=34977167</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=34977167</guid></item><item><title><![CDATA[New comment by Gluber in "“Clean” code, horrible performance"]]></title><description><![CDATA[
<p>I agree with your sentiment. But those things exist (not that that validates the authors argument) and I still shake in terror when during covid I was asked to take a look at a virus spread simulation (cellular automaton) that was written by a university professor and his postdoc team for software engineering at a large university that modeled evey cell in a 100k x 100k grid as a class which used virtual methods for every computation between cells. Rewrote that in Cuda and normal buffers/ arrays.. and an epoch ran in milliseconds instead of hours.</p>
]]></description><pubDate>Tue, 28 Feb 2023 21:56:35 +0000</pubDate><link>https://news.ycombinator.com/item?id=34975462</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=34975462</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=34975462</guid></item><item><title><![CDATA[New comment by Gluber in "“Clean” code, horrible performance"]]></title><description><![CDATA[
<p>You are confounding three separate skills. Finding the right abstractions is an art, whether you write clean code or not. Writing high performance code is another art.<p>A really good developer writes clean code using the right abstraction (finding those tends to take the most time and experience) and drop down to a different level of abstraction for high performance areas where it makes sense.<p>The fact that bad developers suck and write bad code no matter if they use clean code or not does not reflect on the methodology</p>
]]></description><pubDate>Tue, 28 Feb 2023 21:48:55 +0000</pubDate><link>https://news.ycombinator.com/item?id=34975344</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=34975344</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=34975344</guid></item><item><title><![CDATA[New comment by Gluber in "Ask HN: How fast could Google/Baidu create and deploy their ChatGPT equivalent?"]]></title><description><![CDATA[
<p>From an investment standpoint:<p>1. The technology behind it is in the open, and relatively simple ( the models are well understood, and easy to define ) To replicate that ... (with proper engineering etc a good and small team would probably need 1-3 months ) (The model itself could be built in a day )<p>2. Training: Here comes the biggie, training the above model on lots and lots of data is what gives it its quality. This is the bulk of time and cost, and also why smaller companies have a hard time replicating this. We are talking trainings costs in the 9 figures.<p>But 2 does not really matter to those giants tech companies, just smaller competitiors.<p>I would estimate depending on the desired outcome 3-6 months to replicate ChatGPT for those companies.</p>
]]></description><pubDate>Sat, 04 Feb 2023 13:36:40 +0000</pubDate><link>https://news.ycombinator.com/item?id=34654366</link><dc:creator>Gluber</dc:creator><comments>https://news.ycombinator.com/item?id=34654366</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=34654366</guid></item></channel></rss>