Hacker News: I_Nidhi

Whiplash: When people stop taking GLP-1s

I_Nidhi — Fri, 20 Mar 2026 11:12:40 +0000

Article URL: https://nautil.us/whiplash-heart-attack-and-stroke-risk-jumps-when-people-stop-taking-glp-1s-1279029

Comments URL: https://news.ycombinator.com/item?id=47453026

Points: 2

# Comments: 1

Plastic-Eating Bacteria

I_Nidhi — Tue, 17 Mar 2026 10:06:14 +0000

Article URL: https://news.mit.edu/2026/ocean-bacteria-break-down-biodegradable-plastic-0316

Comments URL: https://news.ycombinator.com/item?id=47410624

Points: 4

# Comments: 0

New comment by I_Nidhi in "Daily multivitamin use may slow biological aging: COSMOS trial results"

I_Nidhi — Fri, 13 Mar 2026 13:41:46 +0000

In biological age clocks, the kind COSMOS used, skin is one of the primary tissues researchers use to validate them. Epigenetic methylation patterns in skin cells are among the most studied markers precisely because skin is accessible and responds visibly to the same aging processes the clocks are trying to measure from blood.

The COSMOS trial gives everyone the same pill and measures a whole-body average signal from blood samples. It can't tell you which vitamin drove the effect or where in the body it's acting. It's a limitation of what a broad systemic intervention can tell you. The more targeted work is happening at the tissue level.

In skin specifically, L'Oréal and UC San Diego looked at 1,000+ subjects in 2024 and found that bacterial diversity in the skin microbiome correlates directly with both chronological age and wrinkle depth. They're building these as actual measurable aging biomarkers. Unilever's 2025 study also showed that people whose facial microbiome had higher Acinetobacter and lower Staphylococcus aureus were read as biologically 5–7 years younger. Many other companies are also researching biomarkers for skin anti-aging, and now the longevity trend is being seen in the food industry as well.

Microbiome as a modifiable aging clock is where the real specificity is starting to come from. I work in this space, and we recently mapped where this research is heading. We also did a session exploring the underlying science if you want to go deeper: https://greyb.com/resources/skin-microbiome-beauty/

L'Oréal Study: https://www.frontiersin.org/journals/aging/articles/10.3389/... Unilever Study: https://academic.oup.com/bjd/article/193/Supplement_2/ii24/8...

A Look at "The Phantom Galaxy."

I_Nidhi — Tue, 23 Dec 2025 14:44:35 +0000

Article URL: https://nautil.us/the-heart-of-a-haunting-galaxy-1238491/

Comments URL: https://news.ycombinator.com/item?id=46365669

Points: 3

# Comments: 0

How to Properly Adjust Your Binoculars

I_Nidhi — Tue, 16 Dec 2025 11:51:31 +0000

Article URL: https://www.artofmanliness.com/skills/how-to-adjust-binoculars/

Comments URL: https://news.ycombinator.com/item?id=46287452

Points: 2

# Comments: 0

Bionic Limbs

I_Nidhi — Thu, 27 Nov 2025 08:02:18 +0000

Article URL: https://www.bloomberg.com/news/audio/2025-11-20/bloomberg-businessweek-daily-bionic-limbs-podcast

Comments URL: https://news.ycombinator.com/item?id=46066900

Points: 5

# Comments: 0

AI Trained on Bacterial Genomes

I_Nidhi — Wed, 26 Nov 2025 14:28:20 +0000

Article URL: https://arstechnica.com/science/2025/11/generative-ai-meets-the-genome/

Comments URL: https://news.ycombinator.com/item?id=46057684

Points: 3

# Comments: 0

Creepy AI Toys

I_Nidhi — Wed, 26 Nov 2025 11:05:51 +0000

Article URL: https://www.nytimes.com/2025/08/15/arts/ai-toys-curio-grem.html

Comments URL: https://news.ycombinator.com/item?id=46056236

Points: 2

# Comments: 0

3I/ATLAS: NASA released new images

I_Nidhi — Fri, 21 Nov 2025 10:09:41 +0000

Article URL: https://www.popsci.com/science/3i-atlas-comet-new-photos-nasa/

Comments URL: https://news.ycombinator.com/item?id=46003039

Points: 2

# Comments: 0

A new, high-definition look at our galaxy

I_Nidhi — Fri, 21 Nov 2025 06:41:57 +0000

Article URL: https://nautil.us/new-ai-model-captures-the-milky-way-in-stunning-detail-1248505/

Comments URL: https://news.ycombinator.com/item?id=46001844

Points: 2

# Comments: 0

Why the Earth has tilted 31.5 inches

I_Nidhi — Tue, 18 Nov 2025 11:41:20 +0000

Article URL: https://www.popularmechanics.com/science/environment/a69445743/why-earth-has-tilted-scientific-reason/

Comments URL: https://news.ycombinator.com/item?id=45963853

Points: 8

# Comments: 1

Ask HN: Is it true: An Unreasonable Person Runs the Show?

I_Nidhi — Tue, 18 Nov 2025 11:20:01 +0000

The reasonable person adapts themselves to the world; the unreasonable one persists in trying to adapt the world to themselves. Therefore, all progress depends on unreasonable people. (adapted from George Bernard Shaw)

Comments URL: https://news.ycombinator.com/item?id=45963706

Points: 2

# Comments: 4