Hacker News: aBioGuy

New comment by aBioGuy in "Hacking IKEA Furniture"

aBioGuy — Sun, 30 Aug 2026 13:19:32 +0000

New comment by aBioGuy in "Calvin and Hobbes and the price of integrity"

aBioGuy — Tue, 16 Jun 2026 18:34:24 +0000

Another anecdote (where it came from I do not remember) stuck in my brain was that Watterson's editor called him one day to tell him that STEVEN SPIELBERG was on the phone to talk with him about a Calvin and Hobbes movie. Watterson refused to take the call.

New comment by aBioGuy in "Copper transport drug restores memory and clears toxic Alzheimer's proteins"

aBioGuy — Mon, 15 Jun 2026 16:15:27 +0000

In the title "....in the APP/PS1 Mouse Model of Alzheimer’s Disease"

Given the decades of emphasis on clearing / preventing amyloids I would be fairly jaded. If someone (biotech) wants to spend $$$ chasing this down, good on them.

But a paper curing a mouse model of a human neurological disease does not move the needle for someone with or watching someone suffer from this disease.

New comment by aBioGuy in "MacBook Air with M5"

aBioGuy — Tue, 03 Mar 2026 15:02:57 +0000

The M4 MacBook Air (16gb, 1TB) retailed for $1400 (https://www.bhphotovideo.com/c/product/1884084-REG/apple_mba...).

The M5 equivalent is now $1300. 1TB requires the CPU upgrade.

New comment by aBioGuy in "The Big Vitamin D Mistake (2017)"

aBioGuy — Mon, 28 Jul 2025 00:10:09 +0000

I would like to point out (as I have seen this confused by many non-scientists) that the NIH (National Library of Medicine) provides a service called "PubMed" which collates peer-reviewed (and many pre-print) scientific papers into one database / website. This particular paper (like 99% of the papers on PubMed) was not published by a NIH scientist or by the NIH itself.

New comment by aBioGuy in "Gas pumps freeze at Calgary gas stations [video]"

aBioGuy — Sun, 14 Jan 2024 14:49:26 +0000

Vehicular gas infrastructure is near 100 years of development and still has some edge cases.

EV charging infrastructure is at about 10 years.

New comment by aBioGuy in "Fear of cheap Chinese EVs spurs automaker dash for affordable cars"

aBioGuy — Sun, 10 Dec 2023 04:09:20 +0000

Well a Tern GSD has a max carry weight of 379 lbs and a max speed of 20 mph. Only needs a 0.5 kWh battery too. Has infinite range, depending on your fitness.

New comment by aBioGuy in "Is there anywhere in the world someone can just live for free?"

aBioGuy — Sat, 04 Nov 2023 12:54:48 +0000

No has mentioned that the initial assertion is incorrect? The US Government sent troops to remove native inhabitants. Then they gave the land away. Having an army clear the land ahead of time makes a lot of homesteading possible.

New comment by aBioGuy in "How do we pay for parking?"

aBioGuy — Sat, 19 Aug 2023 22:33:14 +0000

I remember when I moved to DC many years ago we drove to an art exhibit (in an empty building way away from the metro). There was a guy walking up and down the road saying "$5 to park!" I paid him and in the elevator an older woman smugly told me "It's free to park here!" I told her "I know, I'm paying for him to not break MY window." The look on her face....

New comment by aBioGuy in "Electric bike, stupid love of my life"

aBioGuy — Sun, 16 Jul 2023 16:47:30 +0000

Unpopular (?) opinion: don't worry about theft. If you are making developer-money then a $1000-$3000 bike is a trivial amount of money. Just use a cafe-lock with a sturdy chain and go about your life. It gets stolen? Buy a new one. Seems silly to be hesitant on a eBike because of a theoretical concern. Finding an environment where you are reasonably safe from getting murdered by a vehicle should be your primary concern. Everything else is just noise.

New comment by aBioGuy in "Ask HN: What is the most cost effective way to do backups?"

aBioGuy — Thu, 08 Jun 2023 14:32:58 +0000

The cheapest and simplest strategy is to buy several external drives and leave them at work / someone else's house.

New comment by aBioGuy in "Framework Laptop Cupholder Expansion Card"

aBioGuy — Wed, 03 May 2023 03:13:34 +0000

I thought that held the coaster AOL sent everyone in the mail.

New comment by aBioGuy in "Highway EV charging will soon need a ton of power"

aBioGuy — Sun, 11 Dec 2022 16:08:14 +0000

Depending on where you live, you can cargo bike with your kids. If you check out the cargo bike forums there are always posts on how to attach baby seats to a bakfiets and such. I've got two kids and my ecargo-bike replaces about 20 car drives a week.

New comment by aBioGuy in "AWS doesn't make sense for scientific computing"

aBioGuy — Fri, 07 Oct 2022 16:30:15 +0000

Furthermore, scientific computing often (usually?) involves trainees. It can difficult to train people when small mistakes can have five figure bills.

New comment by aBioGuy in "Investigating the effects of bike lanes in Minneapolis"

aBioGuy — Thu, 23 Jun 2022 14:42:59 +0000

If you make it pleasant to ride a bike - people will do it.

Where I live, there is an off-street bike path that was completed about 10 years ago. Since then many new businesses have opened along the path. The economic impact of pulling people OUT OF A CAR and INTO THEIR environment is perhaps under-appreciated.

New comment by aBioGuy in "Cycling is more important than electric cars for reaching net-zero cities"

aBioGuy — Thu, 08 Apr 2021 03:00:41 +0000

The e-bike (pre COVID) would do about 2-3 24 mile trips a week. Plus the local trips. The other 1-2 days were a regular bike. That's a lot of rush hour miles removed from the road.

New comment by aBioGuy in "Cycling is more important than electric cars for reaching net-zero cities"

aBioGuy — Thu, 08 Apr 2021 02:58:44 +0000

Well the car has about 1000 miles in the same time frame. A second (non electric) bike has about 1500 miles. More importantly I was seriously considering replacing the car (it is quite old) but with the cargo bike the car gets used so infrequently now it doesn't seem worth it. Plus if the car does go down we can replace it at a leisurely pace.

New comment by aBioGuy in "Cycling is more important than electric cars for reaching net-zero cities"

aBioGuy — Thu, 08 Apr 2021 02:54:37 +0000

Tern GSD

New comment by aBioGuy in "Cycling is more important than electric cars for reaching net-zero cities"

aBioGuy — Wed, 07 Apr 2021 18:23:48 +0000

I have two little kids. I also own an electric cargo bike. It has replaced over 2,000 car miles in the past year. I can bike to the grocery store, with two kids, and come back with a week's worth of groceries.

New comment by aBioGuy in "Cycling is more important than electric cars for reaching net-zero cities"

aBioGuy — Wed, 07 Apr 2021 18:21:51 +0000

Doesn't this suggest that cities should continue to build out their bike infrastructure? You can't get high bike use without protected lanes / etc.