Feels like two wolves negotiating on how much of the sheep (the sheep is you) they get to eat.

Dare I ask, who is for the "consumer"? If we should even use those words in this system, which in my mind should be for a nation keeping its citizens alive and well both of their own sake and the state's sake.

It doesn't matter what happens 6m-2y down the road, your odds of being laid off or job hopping are high in the current regime so this all makes sense. You pay some amount of your budget to make your life "easier" in the now.

The trouble comes 2-5y down the line when the service is bought out by , and you have to scramble to replace it or hold your nose and pay up.

(tbh, migration is not that hard, but the org will act like it is)

The matrix of authentications, compliances, and intranets will only go up as your company grows and often are enforced by people who do not suffer them daily.

This is ignoring at least these benefits: surgery, development, genetic studies, grafts, anesthesia, and many MANY more. Some non-drug related, some drug adjacent, and they definitely have downstream benefits to humans.

Here's a survey paper with myriad examples: https://pmc.ncbi.nlm.nih.gov/articles/PMC9247923/

I really don't like when bioscience articles land here in HN because they are always commented on with:"in mice", as if to say nothing we see from mouse work works. Well, not everything is software and this kind of work takes years, if not decades. It is real science unfortunately which means that most of it doesn't work! Science, and bioscience specifically, are not efficient systems. In general, the things you do are hard and probably won't work. That doesn't mean you give up.

Animal models are not great, but they are the best progression we can do right now from cell models. And as for being disposable, there are controls on how animals are used in labs in the US: every institution that has animal experimentation has an IACUC (institutional animal care and use committee) that every research proposal must go through, and they do not a rubber stamp your proposal. They want to know why you can't use cell models, and why you can't do it with less or even no animals.

It would be nice if people were a bit more even handed when these types of articles come by. I think HN can do better.

An adage from the lab: "If what we did always worked it would be business, not science."

If your crowning achievement is: "I can 100% all leetcode hards" I have bad news for you.

I was an obsessively good kid, my parents took me everywhere with them and treated me like a peer, within reason. I was well behaved for my age. At the end of the day in kindergarten class, if you didn't cause problems, you received a stamp on your hand. The stamp was everything. A brand that I had ACCOMPLISHED that day.

Nap time was a post lunch, thirty minute time when we turned the lights out and laid down. Some kid near to me was making faces and making weird noises behind the teacher's back during nap time. Of course, he's five, maybe six, so this is not going undetected by our teacher. She storms over and asks "who is making all this noise?". I, being a total narc at 5 simply point. Assuming of course, this means I will receive a daily stamp, maybe even more, for my quick and wonderful detective work.

Then the unthinkable happens. His name goes on the board. MY name goes on the board. A wave of confusion sweeps over me. This is a massive blow to my tiny ego, only bad kids get their name on the board, surely there is a mistake!

It's nap time. I cannot make any noise, else I will risk A CHECKMARK NEXT TO MY NAME, which will only escalate the punishment in 198x to TIME OUT. Bad kids are always in time out. I am NOT a bad kid.

I am crushed. My small brain cannot process the enormity of what has happened. My name is on the board. I am smart enough to know what's not coming.

2pm comes, we're sitting on the square rug, and we're all putting our hands on our heads to receive our daily benediction: the stamp. I desperately keep my hand on my head, hoping I might trick our assistant teacher into giving me what I know is very far away.

She passes right by. I look left and right and realize, there is no mistake.

I held immediately held back a flood of tears, feeling deep failure. I stood up, and slowly gathered my things. I slogged my way to the bus and remember staring out the window thinking, what if the same thing happens tomorrow? I will never receive another stamp under this system, how could they do this to me?! The stamp continued the next day, but a different mark was made.

I had a short villain era after this, realizing a true injustice of the world: no matter how good you are sometimes things will not go your way.

"Something about the whole thing always registered to me as, like, lame—too normcore, too boring, perhaps even too cheugy to an informed and taste-driven millennial ur-consumer like me." -> What even is this? Get over yourself.

Remember that the CEO of Costco wears his name tag to work, and eats the Costco hotdog like everyone else. I'd buy that for a dollar!

There's sometime implicit knowledge in a technique that either doesn't get written down, or someone is so good at something you don't think certain details will matter.

In my old lab (biochemistry) some people just have good hands and are really good at making something repeatable, others not so much.

You lose your job, two years go by, time to sell you your house and move. Hiring is a total circus right now as well, being subjected to a five course hiring obstacle course is a lot of time that you're burning your savings and or missing other opportunities. Compare this to nearly any time since 2012 when it was at most three, and maybe ONE was a technical.

Most people do not save in America, and even when you are employed the health care system does not take great care of you. All of this "choice" is presented as capitalism working, but really it's a set of land mines where two large entities decide how much they want to take from you (the hospital, and the insurance company). Since the pricing is opaque and the amount the insurance company pays is capricious, vaya con dios.

The line feels like don't get sick, and your own country has thrown you to the wolves (they're in on it). Similar to unemployment, and the other "safety nets" not managed centrally or well. Massive delays, and your mortgage is due.

Also, you are paying for all of these safety nets all the time when you are making money, but it is deeply gated when you need it. Sorry for the paragraphs, but watching a friend go through this now and it's very wild.

If you're able to save more than 10%/m, you are very ahead of the game.

As for USA losing the Mandate of Heaven, even people from other countries seem sad to see it happening. Informally, two different groups of Portuguese people I've talked to in the last two weeks in Lisbon had a sentiment of "how could this have happened to such a great country?" Mostly due to the extreme news reports coming from the US, ICE, war, rhetoric etc.

It is a fantastic book, I learned everything I know on Win32 from it. Wrote real time scientific software in windows for ~10y! We did it all, external hardware control, custom UIs, etc. Thanks Ryan Geiss for your timing info.

Right about VC6 was the sweet spot imo, C/C++ with lightning fast UI for docs and more. Tools got out of the way. Once other languages got involved (C#?) the docs got out of control and harder to use, and the UI started to get a little overloaded.

The snappiness of those old windows systems was pretty great.

In my concrete mixer experience that's just one part of the process, lot of other crap goes wrong, forms, vibing, water, additives. I'm not pouring foundations, so my xp is only to say there's a lot going on. Guess it's a first step?

I'm not bidding against you to not train on my data.

Probably a good first step in life extension, I know a lot of first peeks at this came from hypothermic people. Those lessons are now used in heart surgeries to slow metabolism and limit cell deaths.

https://pmc.ncbi.nlm.nih.gov/articles/PMC8297075/

web moves: https://github.com/televator-apps/vimari mouse moves: https://github.com/mjrusso/scoot window moves: https://rectangleapp.com

Drag lock is a good setting, just test drove it and will be using it.

Knowing the right tool for the job is even more powerful now because it will prevent you from going down a rabbit hole the LLM thinks is just fine.

https://mtgbattery.com/

This is the kind of hacking / upgrades I’d love to see. All in cost was about $6k when I last checked probably a little more now. You get a pack teardown, and new CATL cells. Range goes to 400km~.

A lot of this boils down to promo system being so systematized. I've never heard of people in any other field min/max their promotions as hard along with all of the expert jargon in any other field I've worked in. Packets, peers, comp, other co comps, what your boss thinks of you, what your boss thinks of your peers (nee: competitors), and the inevitable crash out when they don't get the promotion. All part of the bigco experience! I feel like when we systematized comp into ranks Lx, Ly we gave up our leverage a little bit.