Hacker News: anon1253

An attempt at explaining bipolar disorder and psychosis

anon1253 — Sun, 03 May 2026 12:58:25 +0000

Article URL: https://osf.io/w28g9_v1

Comments URL: https://news.ycombinator.com/item?id=47996521

Points: 2

# Comments: 0

An attempt at explaining bipolar disorder and psychosis

anon1253 — Mon, 27 Apr 2026 09:00:28 +0000

Article URL: https://osf.io/preprints/psyarxiv/w28g9_v1

Comments URL: https://news.ycombinator.com/item?id=47919269

Points: 4

# Comments: 0

Show HN: Llamora, a local-first journaling environment

anon1253 — Sun, 22 Feb 2026 15:41:46 +0000

Article URL: https://github.com/joelkuiper/Llamora

Comments URL: https://news.ycombinator.com/item?id=47111880

Points: 1

# Comments: 0

New comment by anon1253 in "Prism"

anon1253 — Wed, 28 Jan 2026 07:44:26 +0000

Slightly off-topic but related: currently I'm in a research environment (biomedicine) where a lot of AI is used. Sometimes well, often poorly. So as an exercise I drafted some rules and commitments about AI and research ("Research After AI: Principles for Accelerated Exploration" [1]), I took the Agile manifesto as a starting point. Anyways, this might be interesting as a perspective on the problem space as I see it.

[1] https://gist.github.com/joelkuiper/d52cc0e5ff06d12c85e492e42...

Research After AI: Principles for Accelerated Exploration

anon1253 — Sat, 24 Jan 2026 22:28:42 +0000

Article URL: https://gist.github.com/joelkuiper/d52cc0e5ff06d12c85e492e4295ca890

Comments URL: https://news.ycombinator.com/item?id=46748372

Points: 1

# Comments: 0

AI and academic research: the Manifesto for Accelerated Exploration

anon1253 — Sat, 24 Jan 2026 08:07:44 +0000

Article URL: https://gist.github.com/joelkuiper/d52cc0e5ff06d12c85e492e4295ca890

Comments URL: https://news.ycombinator.com/item?id=46741901

Points: 1

# Comments: 0

Llamora is an experimental, local-first diary companion

anon1253 — Thu, 28 Aug 2025 10:07:09 +0000

Article URL: https://github.com/joelkuiper/Llamora

Comments URL: https://news.ycombinator.com/item?id=45050369

Points: 1

# Comments: 0

Show HN: A minimal Flask and Htmx and LangChain (with llama.cpp) interface

anon1253 — Mon, 04 Aug 2025 15:22:38 +0000

Article URL: https://github.com/joelkuiper/flask-htmx-llm

Comments URL: https://news.ycombinator.com/item?id=44787104

Points: 1

# Comments: 0

I wrote a book [Dutch/NL][pdf]

anon1253 — Sat, 20 Jan 2024 08:01:13 +0000

Article URL: https://entoenvoormijnlotgenoten.nl/files/book.pdf

Comments URL: https://news.ycombinator.com/item?id=39065581

Points: 4

# Comments: 1

New comment by anon1253 in "Subsec fluctuations in extracellular dopamine encode prediction errors in humans"

anon1253 — Sun, 10 Dec 2023 10:25:28 +0000

It always fascinated me how a lot of "state" in our neural networks is probably encoded in the extracellular fluids rather than in the neurons themselves. Biological neural networks really do not like it if you swap out their fluids (you can do this experimentally in vitro). For me it has always been one of those "nature really doesn't care about complexity" things ... it will just use whatever tools are available with little to no regard for our understanding of "boundaries". I'm not saying this complexity is strictly needed for intelligence (however that is defined) ... but I do always find it a little bit dishonest when scientists (and especially those working with pharmaceuticals) "zoom in" to the cells and then usually promptly forget that those cells are part of the much wider stage of tissues and eventually even everything outside the confines of our skin. Anyway, just my two cents.

New comment by anon1253 in "Multifaceted: The linguistic echo chambers of LLMs"

anon1253 — Sun, 03 Dec 2023 10:47:13 +0000

It's a fascinating topic. I've often been surprised by its use of "tapestry" (as in "the tapestry of existence") and I never really figured out why it seems to gravitate towards such a relatively uncommon phrase. As usual I am reading too much into it (seemingly the logit for "tapestry" was higher than the others), but why? And what do these preferences tell us about the LLMs more generally? Anyway, fascinating!

New comment by anon1253 in "Ask HN: What are some unpopular technologies you wish people knew more about?"

anon1253 — Sat, 02 Dec 2023 15:52:23 +0000

RDF and semantic web used to be my goto's for this, as I believe many of the core ideas are still valid and often overlooked and sometimes even poorly re-implemented. Which says something.

However, lately I've come to like llama.cpp and friends, yes it's not ChatGTP miracle whatever but how often do you /actually/ need that? Despite its tremendous popularity, it still seems like something more people should know about. For me, I've had great fun with running LLMs locally and experiencing their different "flavors" from a more "phenomenological" (what is it like to use them) perspective rather than a technological one.

A chat about "the process of reality appears mental"

anon1253 — Fri, 17 Nov 2023 15:25:14 +0000

Article URL: https://chat.openai.com/share/ea0dab81-2cb1-465a-be27-84ab7460b846

Comments URL: https://news.ycombinator.com/item?id=38304837

Points: 1

# Comments: 0

Stupid Ideas Revived: a chat about consciousness and reality

anon1253 — Thu, 09 Nov 2023 19:25:49 +0000

Article URL: https://chat.openai.com/share/8a4a3085-4668-40af-86fa-f2a5dbb40d4b

Comments URL: https://news.ycombinator.com/item?id=38209692

Points: 2

# Comments: 0

A chat about therapy, Metzinger, Kastrup, and Whitehead

anon1253 — Wed, 08 Nov 2023 08:48:38 +0000

Article URL: https://chat.openai.com/share/06753ce3-3fae-4aa5-b442-5341c6aba1cb

Comments URL: https://news.ycombinator.com/item?id=38188075

Points: 1

# Comments: 0

New comment by anon1253 in "Mistral 7B"

anon1253 — Sun, 15 Oct 2023 19:10:09 +0000

Code is up https://github.com/vortext/esther but it's still heavily work in progress :-)

Show HN: Esther, an idea for a diary app that embeds an LLM

anon1253 — Sun, 15 Oct 2023 16:59:26 +0000

Article URL: https://github.com/vortext/esther

Comments URL: https://news.ycombinator.com/item?id=37891397

Points: 11

# Comments: 0

New comment by anon1253 in "Ask HN: Show me your half baked project"

anon1253 — Thu, 12 Oct 2023 17:47:09 +0000

https://github.com/vortext/esther

Esther is my personal project to develop a diary app that talks back. Basically. Along the way I learned how to htmx, llama.cpp via JNA and practical experience with LLMs. I suffer from type-1 bipolar disorder with psychoses and normal life just ain't gonna happen. So unemployed, single, #nolife ... I decided to build a chat bot for myself. It's not finished the RAG stuff still needs implementing, but oh well. It's written in Clojure on GraalVM (because I wanted to try polyglot) other than that it's nothing /too/ fancy ... but it feels great having an LLM + UI you can just build the way you like it

New comment by anon1253 in "Mistral 7B"

anon1253 — Wed, 11 Oct 2023 18:27:15 +0000

Cool! And on top of that TheBloke has the quantized models of course:

https://huggingface.co/TheBloke/Mistral-7B-v0.1-GGUF

https://huggingface.co/TheBloke/Mistral-7B-OpenOrca-GGUF

https://huggingface.co/TheBloke/Mistral-7B-Instruct-v0.1-GGU...

I typically run my models with the 5_K_M or 6_K quantization, but it really depends on the use case and requirements

New comment by anon1253 in "Mistral 7B"

anon1253 — Wed, 11 Oct 2023 18:12:38 +0000

Probably soon! I'll post it here. Still finalizing some Retrieval Augmented Generation things. It's written in Clojure with a very thin HTMX front-end. However there are some interesting things like using gbnf grammar constraints creatively for chain-of-thought reasoning. It's a one-person job though but I've always wanted a diary that feels like someone to talk to, and the tech is finally here!