Hacker News: archimedes237

New comment by archimedes237 in "U.S. researchers face new restrictions on publishing with foreign collaborators"

archimedes237 — Fri, 22 May 2026 22:23:53 +0000

"a lot" must mean 99% either directly through grants or indirectly by the gov paying the universities directly.

New comment by archimedes237 in "Alberta to hold referendum on whether to remain in Canada"

archimedes237 — Fri, 22 May 2026 14:36:18 +0000

It is technically possible to separate legally, but there are so many intentional roadblocks that it is effectively impossible to do so.

New comment by archimedes237 in "AI has a multiplying effect on existing technical skills"

archimedes237 — Fri, 22 May 2026 14:31:36 +0000

I know someone who got AI to make a full minecraft bot gui that will put down waypoints for people to see and dig at and then do an in-game dig search (bot uses jsmacros) and they know zero coding.

New comment by archimedes237 in "How Mark Klein told the EFF about Room 641A [book excerpt]"

archimedes237 — Fri, 01 May 2026 15:06:27 +0000

Exactly. I love reading on this site . Written while im on the public bus.

New comment by archimedes237 in "Intelligence Evolved at Least Twice in Vertebrate Animals"

archimedes237 — Thu, 10 Apr 2025 13:58:09 +0000

It can if having non-dead grandparents gives an advantage before reproduction occurs. Could be why we live longer than most species too.

New comment by archimedes237 in "The Road Not Taken Is Guaranteed Minimum Income"

archimedes237 — Fri, 21 Mar 2025 16:49:18 +0000

The government doesn't do anything. It is the people that do. If the poor people all choose to live off UBI then who will be building these giant housing blocks since it isn't the rich people that build housing?

New comment by archimedes237 in "'It's a Heist': Real Federal Auditors Are Horrified by Doge"

archimedes237 — Tue, 18 Mar 2025 21:17:21 +0000

A lot of people wouldn't be able to manage it personally if they had a 401k even if they had the best of intentions.

New comment by archimedes237 in "Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects"

archimedes237 — Fri, 07 Mar 2025 19:05:27 +0000

Note, I have access but this is not my field. I just asked ChatGPT your question after have it read the paper. This is what the response was:

Yes, the paper provides the 12-mer amino acid sequence of BRP: THRILRRLFNLC .

Regarding post-translational modifications, the BRP peptide was synthesized with a C-terminal amidation, which was critical for its bioactivity. The non-amidated version of BRP was inactive in vitro . Additionally, the paper mentions that the C-terminal cysteine (C12) was synthesized as a free thiol .

So, BRP is not just a simple peptide—it has a key post-translational modification (C-terminal amidation) that influences its function.