Hacker News: bibouthegreat

New comment by bibouthegreat in "Clinical failure rates over the decades: yikes"

bibouthegreat — Sun, 26 Jul 2026 23:18:32 +0000

People get confused about all the types of clinical trials. The worst part happened in 1997 [1] Before this time, you could p-hack your studies. You could get a molecule and just look at some random effect that happens in any case because of sampling issues. Since 1997, you must register the full protocol to the FDA before the study. Since then, almost no study with a full protocol brought a really new medicine.

[1] https://en.wikipedia.org/wiki/Food_and_Drug_Administration_M...

New comment by bibouthegreat in "I baked a pie every day for a year"

bibouthegreat — Fri, 27 Feb 2026 03:18:00 +0000

Or even brew beers and meads.

New comment by bibouthegreat in "I baked a pie every day for a year"

bibouthegreat — Fri, 27 Feb 2026 03:16:42 +0000

Cooking is art, baking is a very easy science (weight things and check the temperature), pastry is another thing. That requires talent, experience and a lucky star.

New comment by bibouthegreat in "Does the market return 10% on average?"

bibouthegreat — Sun, 21 Dec 2025 23:49:06 +0000

From what I see, I'd bet the author is not taking into account dividends and other things. What you should look at is the "Total Return" c.f. https://tradethatswing.com/average-historical-stock-market-r...

New comment by bibouthegreat in "An Intuitive Explanation of Black–Scholes"

bibouthegreat — Sun, 06 Oct 2024 01:05:00 +0000

2 parts:

1. Interest rates can be negative 2. Volatility reduces the average. Take an example of +10% then -10% (1+0.1)*(1-0.1) = 1 - 0.1² = 0.99 < 1. It's due to the "log normal returns"

New comment by bibouthegreat in "Own Constant Folder in C/C++"

bibouthegreat — Sun, 23 Jun 2024 00:14:27 +0000

I wonder what it would be with a constexpr. If it works, it would be good to add this to intrinsic functions

Bluetooth "Just Works" security breach

bibouthegreat — Sun, 31 Mar 2024 17:02:40 +0000

Article URL: https://www.mobile-hacker.com/2024/03/22/bluetooth-vulnerability-allows-unauthorized-user-to-record-and-play-audio-on-bluetooth-speakers/

Comments URL: https://news.ycombinator.com/item?id=39885912

Points: 3

# Comments: 0

New comment by bibouthegreat in "Ask HN: Who's getting their job applications rejected?"

bibouthegreat — Thu, 28 Mar 2024 14:00:04 +0000

Do you have a resume?

New comment by bibouthegreat in "Gnome Receives €1M from German Government"

bibouthegreat — Sat, 11 Nov 2023 17:26:21 +0000

Fun fact: Rolex is a non-profit.

New comment by bibouthegreat in "Ask HN: Considering colocated hosting over cloud, what should I know?"

bibouthegreat — Sun, 18 Apr 2021 21:54:34 +0000

Those guys do a pretty good service. They have presence in London (Brick lane) and Midlands. They also do dedicated servers. https://www.veloxserv.co.uk/

Remember that a colo means that if you have a hardware issue, you have to go there so have one close to you. Otherwise, there are "remote hands" you can hire per hour.

Also, if you don't have a specific hardware need, it's likely that a dedicated server would be enough. If there's a problem, you always can swap it for another one in a very short time. If it's our hardware, you're responsible of everything and that might not bring any positive point on your side.