<rss version="2.0" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Hacker News: biophysboy</title><link>https://news.ycombinator.com/user?id=biophysboy</link><description>Hacker News RSS</description><docs>https://hnrss.org/</docs><generator>hnrss v2.1.1</generator><lastBuildDate>Mon, 25 May 2026 00:10:19 +0000</lastBuildDate><atom:link href="https://hnrss.org/user?id=biophysboy" rel="self" type="application/rss+xml"></atom:link><item><title><![CDATA[New comment by biophysboy in "The last six months in LLMs in five minutes"]]></title><description><![CDATA[
<p>Protein structure is not a rate-limiting step in drug discovery.</p>
]]></description><pubDate>Tue, 19 May 2026 13:10:04 +0000</pubDate><link>https://news.ycombinator.com/item?id=48192849</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=48192849</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48192849</guid></item><item><title><![CDATA[New comment by biophysboy in "I believe there are entire companies right now under AI psychosis"]]></title><description><![CDATA[
<p>The way I put this to myself is that AI gives “correct correct answers and incorrect correct answers”.<p>They almost always generate logically correct text, but sometimes that text has a set of incorrect implicit assumptions and decisions that may not be valid for the use case.<p>Generating a correct correct solution requires proper definition of the problem, which is arguably more challenging than creating the solution.</p>
]]></description><pubDate>Fri, 15 May 2026 21:56:12 +0000</pubDate><link>https://news.ycombinator.com/item?id=48154424</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=48154424</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48154424</guid></item><item><title><![CDATA[New comment by biophysboy in "A message from President Kornbluth about funding and the talent pipeline"]]></title><description><![CDATA[
<p>Yes, I hear you on how academia chases metrics. I would argue this phenomena is not worse than Company Z making a boilerplate AI chat tool that is no more useful than the flagship popular products. I think the fairest comparison is comparing the best researchers in academia/industry. I think they accomplish different things because they have different goals/incentives.</p>
]]></description><pubDate>Thu, 14 May 2026 18:22:27 +0000</pubDate><link>https://news.ycombinator.com/item?id=48139182</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=48139182</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48139182</guid></item><item><title><![CDATA[New comment by biophysboy in "A message from President Kornbluth about funding and the talent pipeline"]]></title><description><![CDATA[
<p>Transformers are an applied science: <a href="https://patents.google.com/patent/US10740433B2/en" rel="nofollow">https://patents.google.com/patent/US10740433B2/en</a><p>Basic research would be something like optimal control theory, which came well before the transformer design.<p>I'm not trying to be evasive; I can see how my distinction could be seen as conveniently just outside industry's purview. Put it this way: I think companies, particularly small ones, are incentivized to pursue well-known methods/materials. Innovation modulates and optimizes.</p>
]]></description><pubDate>Thu, 14 May 2026 18:15:41 +0000</pubDate><link>https://news.ycombinator.com/item?id=48139085</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=48139085</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48139085</guid></item><item><title><![CDATA[New comment by biophysboy in "A message from President Kornbluth about funding and the talent pipeline"]]></title><description><![CDATA[
<p>Departments base grad school admissions on grant awards. The article states: grant awards for MIT went down more than 20%, then new MIT grad students went down 20%. The decrease in students has nothing to do with academia being detached from industry.</p>
]]></description><pubDate>Thu, 14 May 2026 16:31:45 +0000</pubDate><link>https://news.ycombinator.com/item?id=48137714</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=48137714</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48137714</guid></item><item><title><![CDATA[New comment by biophysboy in "A message from President Kornbluth about funding and the talent pipeline"]]></title><description><![CDATA[
<p>It is a real shame too, because industry is completely incapable of doing basic research. Universities make the fuzzy ideas, and companies turn them into widgets. The only exceptions in history to this are the monopolies, which have their own obvious problems. They cannot produce non-rival, non-excludable goods - stuff that's hard to patent.</p>
]]></description><pubDate>Thu, 14 May 2026 16:03:11 +0000</pubDate><link>https://news.ycombinator.com/item?id=48137345</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=48137345</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48137345</guid></item><item><title><![CDATA[New comment by biophysboy in "MIT: 20% drop in incoming graduate students"]]></title><description><![CDATA[
<p>Obviously there is a selection effect that confounds any causal comparisons between those who do and do not get into MIT. But the better counterfactual is students who are accepted but do not attend. A diff-in-diff study with these two groups would be a better test. There are unique features of MIT: more money, elite network, etc. I do share your skepticism though - I've worked w/ MIT people before. I think they are very smart but also very lucky.</p>
]]></description><pubDate>Thu, 14 May 2026 15:57:34 +0000</pubDate><link>https://news.ycombinator.com/item?id=48137274</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=48137274</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48137274</guid></item><item><title><![CDATA[New comment by biophysboy in "EU to crack down on TikTok, Instagram's 'addictive design' targeting kids"]]></title><description><![CDATA[
<p>This is all true, but I think the main cost is the time wasted. The opportunity cost is enormous for humanity.</p>
]]></description><pubDate>Tue, 12 May 2026 14:43:23 +0000</pubDate><link>https://news.ycombinator.com/item?id=48109043</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=48109043</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48109043</guid></item><item><title><![CDATA[New comment by biophysboy in "EU to crack down on TikTok, Instagram's 'addictive design' targeting kids"]]></title><description><![CDATA[
<p>Albert Hirschman wrote a great book about the rhetoric people use to stifle policy proposals 35 years ago. “It’s futile; it won’t ever work” is one common argument. It’s not a meme so much as a cynical reflexive intuition</p>
]]></description><pubDate>Tue, 12 May 2026 12:51:08 +0000</pubDate><link>https://news.ycombinator.com/item?id=48107532</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=48107532</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48107532</guid></item><item><title><![CDATA[New comment by biophysboy in "Agents for financial services and insurance"]]></title><description><![CDATA[
<p>pulling back as in setting more realistic token budgets, or something more drastic? I'm curious</p>
]]></description><pubDate>Tue, 05 May 2026 16:02:35 +0000</pubDate><link>https://news.ycombinator.com/item?id=48024353</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=48024353</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48024353</guid></item><item><title><![CDATA[New comment by biophysboy in "iOS 27 is adding a 'Create a Pass' button to Apple Wallet"]]></title><description><![CDATA[
<p>Entry ticket, basically. I went to Olympic Natl park recently and had the pass added to my Apple Wallet.</p>
]]></description><pubDate>Tue, 05 May 2026 13:24:56 +0000</pubDate><link>https://news.ycombinator.com/item?id=48022241</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=48022241</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48022241</guid></item><item><title><![CDATA[New comment by biophysboy in "iOS 27 is adding a 'Create a Pass' button to Apple Wallet"]]></title><description><![CDATA[
<p>I don't really think of it as an app; I think of it as the "double-tap side button to do tap to pay or present my ticket" iPhone feature</p>
]]></description><pubDate>Tue, 05 May 2026 13:22:46 +0000</pubDate><link>https://news.ycombinator.com/item?id=48022213</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=48022213</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48022213</guid></item><item><title><![CDATA[New comment by biophysboy in "California to begin ticketing driverless cars that violate traffic laws"]]></title><description><![CDATA[
<p>Fair point - a combo might be the best approach.. I understand the idea of accidents correlating w/ miles driven, but it seems to be optimizing for driving safety rather than human life? Does that make sense?</p>
]]></description><pubDate>Sun, 03 May 2026 02:45:39 +0000</pubDate><link>https://news.ycombinator.com/item?id=47992822</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=47992822</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47992822</guid></item><item><title><![CDATA[New comment by biophysboy in "California to begin ticketing driverless cars that violate traffic laws"]]></title><description><![CDATA[
<p>Honestly, just per 1M person per year. If this normal incidence went up while the exposure incidence rate went down over 20 years, I'd wanna know.</p>
]]></description><pubDate>Sun, 03 May 2026 02:43:05 +0000</pubDate><link>https://news.ycombinator.com/item?id=47992804</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=47992804</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47992804</guid></item><item><title><![CDATA[New comment by biophysboy in "California to begin ticketing driverless cars that violate traffic laws"]]></title><description><![CDATA[
<p>Coming from a bio background, I’ve always been confused why auto fatality stats are normalized per miles driven. Epidemiological metrics like incidence or prevalence seem like they would work fine? Town A would be “safer” than town B if people’s commutes are 20% shorter, even if accidents occur w same frequency</p>
]]></description><pubDate>Sat, 02 May 2026 20:23:19 +0000</pubDate><link>https://news.ycombinator.com/item?id=47990102</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=47990102</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47990102</guid></item><item><title><![CDATA[New comment by biophysboy in "Kyoto cherry blossoms now bloom earlier than at any point in 1,200 years"]]></title><description><![CDATA[
<p>A better time range would be the average species lifespan of the plants and animals we eat. Too short a range highlights noise; too long a range highlights unrelated data.</p>
]]></description><pubDate>Wed, 29 Apr 2026 21:36:52 +0000</pubDate><link>https://news.ycombinator.com/item?id=47955070</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=47955070</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47955070</guid></item><item><title><![CDATA[New comment by biophysboy in "Sabotaging projects by overthinking, scope creep, and structural diffing"]]></title><description><![CDATA[
<p>I finished a PhD. My concrete advice is focus on feasible methods you know are realistic for your lab resource wise (time, money, etc)</p>
]]></description><pubDate>Sat, 25 Apr 2026 15:00:18 +0000</pubDate><link>https://news.ycombinator.com/item?id=47901997</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=47901997</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47901997</guid></item><item><title><![CDATA[New comment by biophysboy in "DuckDB 1.5.2 – SQL database that runs on laptop, server, in the browser"]]></title><description><![CDATA[
<p>Along with parsing various file formats, you can create duckdb files to store tables, and make related views, schema, etc. They also have a newer ducklake tool</p>
]]></description><pubDate>Wed, 22 Apr 2026 20:47:34 +0000</pubDate><link>https://news.ycombinator.com/item?id=47869108</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=47869108</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47869108</guid></item><item><title><![CDATA[New comment by biophysboy in "Anthropic says OpenClaw-style Claude CLI usage is allowed again"]]></title><description><![CDATA[
<p>I think a good corollary idea to "vibe coding" is the "vibe product". There is so much stuff popping in and out of existence and my excitement has declined.</p>
]]></description><pubDate>Tue, 21 Apr 2026 17:45:15 +0000</pubDate><link>https://news.ycombinator.com/item?id=47852004</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=47852004</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47852004</guid></item><item><title><![CDATA[New comment by biophysboy in "Book review: There Is No Antimemetics Division"]]></title><description><![CDATA[
<p>Is this book just riffing about embedding space? I thought about reading it eventually, but the quoted passage is kind of annoying/tedious</p>
]]></description><pubDate>Mon, 06 Apr 2026 18:04:53 +0000</pubDate><link>https://news.ycombinator.com/item?id=47664556</link><dc:creator>biophysboy</dc:creator><comments>https://news.ycombinator.com/item?id=47664556</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47664556</guid></item></channel></rss>