https://en.wikipedia.org/wiki/The_Last_Question

https://shademap.app/@40.75481,-73.98696,14.82042z,171702794...

https://www.amnh.org/research/hayden-planetarium/manhattanhe...

    In April 1993, Don Calhoun made a miraculous full-court shot during a Chicago Bulls game to win $1 million. He was an average office supply salesman but felt calm and destined to make the nearly impossible shot.
    The shot went viral and sparked a boom in in-game contests at sporting events. Companies like SCA Promotions started insuring these big-money contests, which remained popular crowd pleasers.
    Calhoun initially feared he wouldn't get the money because he had played some college basketball recently. This violated a common rule that contestants couldn't have played the sport recently.
    The Bulls held a press conference saying they would pay Calhoun the $1 million regardless of the insurance outcome. Later, Michael Jordan privately told Calhoun that the Bulls players had pressured the insurance company to pay him.
    Calhoun got Jordan to sign the winning ball years later after persistence. He kept the autographed ball not as a collectible but for his kids to play with, symbolizing how the shot changed their family's trajectory.
    The $1 million was paid out as $50k checks over 20 years. It provided a nice supplement to Calhoun's middle-class lifestyle but did not make him wealthy. The experience and memories were priceless.

I thought this was such a fabulous idea, I bought a domain name for it: https://inmytown.org/ As usual, I just haven't done all the other hard work. But, in the old days last year, I thought it would be cool for local shops to have an online presence so that online shoppers could see where to buy stuff and place orders and then pick it up. So, have an e-commerce platform for shops, restaurants, delivery would be great. Try and keep money local instead of shaving 10-20% off of all transactions and sending them to big tech. Does anyone want to help me build this? Totally committed to non-profit and great apps for local companies.

But, about 30 genomic mutations are spontaneous every generation. I have one that causes brittle bone disease. So, just knowing the parents' genomic profile and screening out with IVF will not be sufficient.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322360/

In there, they did work on A549 cell lines and showed that removing nutrients from the media decreased their growth rate. They also showed that putting these human cell lines into immune deficient mice and doing a couple 24hr fasts per week had a small (p=0.03) effect on the tumor growth rate (Fig 2). But in the in vivo study, it appears they didn't directly compare A549 vs cisplatin resistant A549 - they seemed to have run 2 studies both vs control.

There are literally thousands of papers showing drugs or treatments which can cure lab mice of "cancer" and many more which can kill cell lines in vivo, but only a tiny percentage of those work in patients. There is a reason this is not in a higher profile journal.

Notice it says one fatality per "320 million miles in vehicles equipped with Autopilot hardware." But, how many of those miles (or what percent of the time) does a Tesla driver use Autopilot? Also, maybe those good stats are due to the structural safety features and not the autopilot. It may be more fair to compare to other cars with excellent crash protection but no autopilot.

I think it would be a great service to the world to improve driving safety, but maybe we need to really start looking at the stats and get some more hubris as we transition to full autopilot. For example, require that drivers keep their hands on the wheel and eyes on the road. When more cars have autopilot, then mesh behavior between vehicles, and e-road features, then maybe we'll be more ready for driver-less cars.

The University of California, Los Angeles, owns a U.S. patent (6,274,119) entitled “Methods for Labeling ß-Amyloid Plaques and Neurofibrillary Tangles”, which has been licensed to TauMark, LLC. Drs. Small, Satyamurthy, Huang, and Barrio are among the inventors and have financial interest in TauMark, LLC. Dr. Small also reports having served as an advisor to and/or having received lecture fees from Allergan, Argentum, Axovant, Cogniciti, Forum Pharmaceuticals, Herbalife, Janssen, Lundbeck, Lilly, Novartis, Otsuka, and Pfizer. Dr. Heber reports receiving consulting fees from Herbalife, and the McCormick Science Institute. The manufacturer of Theracurmin, Theravalues Corporation, provided the Theracurmin and placebo for the trial, funds for laboratory testing of blood curcumin levels, and funds for Dr. Small's travel to the 2017 Alzheimer's Association International Conference for presentation of the findings.

How will the investors feel if they know that you would sell 5% of the company for $100k? Maybe this is your leverage: the investors will know the price of the buyout and since the investors know that you are very familiar with the company, then they will invest less. Therefore, the CEO should offer you a fair price for your shares.