<rss version="2.0" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Hacker News: chromatin</title><link>https://news.ycombinator.com/user?id=chromatin</link><description>Hacker News RSS</description><docs>https://hnrss.org/</docs><generator>hnrss v2.1.1</generator><lastBuildDate>Sat, 16 May 2026 10:41:06 +0000</lastBuildDate><atom:link href="https://hnrss.org/user?id=chromatin" rel="self" type="application/rss+xml"></atom:link><item><title><![CDATA[New comment by chromatin in "Software Developers Say AI Is Rotting Their Brains"]]></title><description><![CDATA[
<p>Is this substantially different, cognitively or skills-wise, than moving into management and directing a team to write code, but no longer writing code oneself?</p>
]]></description><pubDate>Wed, 13 May 2026 14:50:06 +0000</pubDate><link>https://news.ycombinator.com/item?id=48122696</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=48122696</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48122696</guid></item><item><title><![CDATA[New comment by chromatin in "Claude Platform on AWS"]]></title><description><![CDATA[
<p>"Practice is policy"</p>
]]></description><pubDate>Tue, 12 May 2026 15:02:35 +0000</pubDate><link>https://news.ycombinator.com/item?id=48109369</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=48109369</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48109369</guid></item><item><title><![CDATA[New comment by chromatin in "US inflation jumps to 3.8% as energy costs surge from Iran war"]]></title><description><![CDATA[
<p>I disagree and think GP poster is right on the money.<p>There are many ways in which inflation numbers are cooked; just one of them is the hedonic adjustment [1].<p>Others include an un-representative basket of goods.<p>The basket of goods is adjusted every 2 years, but not necessarily in a way that mirrors the way real households adapt their spending patterns to increased prices.<p>Owner equivalent rent (LOL) massively lags behind home prices.<p>Honestly, when 10s or hundreds of millions of people's perception does not match *Official Government Numbers*, then it's reason to suspect that the official numbers are a poor metric.<p>[1] <a href="https://www.bls.gov/cpi/quality-adjustment/" rel="nofollow">https://www.bls.gov/cpi/quality-adjustment/</a></p>
]]></description><pubDate>Tue, 12 May 2026 14:54:05 +0000</pubDate><link>https://news.ycombinator.com/item?id=48109215</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=48109215</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48109215</guid></item><item><title><![CDATA[New comment by chromatin in "Google releases Gemma 4 open models"]]></title><description><![CDATA[
<p>I love that you are doing this test. However, as it purports to be a test of "English-to-SQL", your hardest question (Q9) seems ungrammatical:<p>> Show order lines, revenue, units sold, revenue per unit (total revenue ÷ total units sold), average list price per product in the subcategory, 
gross profit, and margin percentage for each product subcategory.<p>In particular, the clause "in the subcategory, gross profit, and margin percentage for each product subcategory" is ambiguous, and I wonder if more models would pass if the English were reformulated to be correct.<p>(it's also notable that Claude Opus 4.6 and Sonnet 4.6 both "missed" this one)</p>
]]></description><pubDate>Sat, 04 Apr 2026 11:13:53 +0000</pubDate><link>https://news.ycombinator.com/item?id=47638024</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=47638024</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47638024</guid></item><item><title><![CDATA[New comment by chromatin in "Show HN: An open-source safety net for home hemodialysis"]]></title><description><![CDATA[
<p>Incredible; I'll let my patients* on Home HD know about this.<p>*not a nephrologist but have several pts on home hd</p>
]]></description><pubDate>Fri, 20 Mar 2026 19:44:25 +0000</pubDate><link>https://news.ycombinator.com/item?id=47459621</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=47459621</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47459621</guid></item><item><title><![CDATA[New comment by chromatin in "Delve – Fake Compliance as a Service"]]></title><description><![CDATA[
<p>> Delve was founded in 2023 by Karun Kaushik and Selin Kocalar, both Forbes 30 Under 30 members and MIT dropouts who met as freshmen.<p>Forbes 30 under 30 remains undefeated</p>
]]></description><pubDate>Fri, 20 Mar 2026 19:37:20 +0000</pubDate><link>https://news.ycombinator.com/item?id=47459540</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=47459540</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47459540</guid></item><item><title><![CDATA[New comment by chromatin in "GPT‑5.3 Instant"]]></title><description><![CDATA[
<p>No, not at all. My unqualified internet diagnosis is that you may have high anxiety.</p>
]]></description><pubDate>Wed, 04 Mar 2026 22:36:40 +0000</pubDate><link>https://news.ycombinator.com/item?id=47254951</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=47254951</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47254951</guid></item><item><title><![CDATA[New comment by chromatin in "Sheldon Brown's Bicycle Technical Info"]]></title><description><![CDATA[
<p>When I was a young(er) postdoc and had to overhaul my bicycle -- my main transportation to work-- this site was invaluable. Forever grateful to Sheldon.</p>
]]></description><pubDate>Fri, 06 Feb 2026 18:24:05 +0000</pubDate><link>https://news.ycombinator.com/item?id=46916270</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=46916270</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=46916270</guid></item><item><title><![CDATA[New comment by chromatin in "The 600-year-old origins of the word 'hello'"]]></title><description><![CDATA[
<p>> According to linguists, elongated variations such as "heyyy" could be construed as flirtatious, "hellaw" might suggest you're from the southern US,<p>I am from the Southern US and I am definitely not familiar with this phonetic form. Could be what a BBC writer _imagines_ a Southerner sounds like</p>
]]></description><pubDate>Sat, 17 Jan 2026 16:46:58 +0000</pubDate><link>https://news.ycombinator.com/item?id=46659487</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=46659487</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=46659487</guid></item><item><title><![CDATA[New comment by chromatin in "Nabokov's guide to foreigners learning Russian"]]></title><description><![CDATA[
<p>I found Croatian significantly easier than Czech, perhaps because of centuries (millenia?) of trans-Adriatic Italian influence?</p>
]]></description><pubDate>Wed, 24 Dec 2025 15:46:27 +0000</pubDate><link>https://news.ycombinator.com/item?id=46376538</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=46376538</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=46376538</guid></item><item><title><![CDATA[New comment by chromatin in "Unifi Travel Router"]]></title><description><![CDATA[
<p>Time is your most precious commodity.</p>
]]></description><pubDate>Wed, 24 Dec 2025 15:03:49 +0000</pubDate><link>https://news.ycombinator.com/item?id=46376174</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=46376174</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=46376174</guid></item><item><title><![CDATA[New comment by chromatin in "Self-hosting a Matrix server for 5 years"]]></title><description><![CDATA[
<p>Conduit [1] has retention policies [2] for media and attachments!<p>[1] <a href="https://conduit.rs/" rel="nofollow">https://conduit.rs/</a> and <a href="https://gitlab.com/famedly/conduit" rel="nofollow">https://gitlab.com/famedly/conduit</a>
[2] <a href="https://gitlab.com/famedly/conduit/-/blob/next/docs/configuration.md#retention-policies" rel="nofollow">https://gitlab.com/famedly/conduit/-/blob/next/docs/configur...</a></p>
]]></description><pubDate>Mon, 01 Dec 2025 21:51:18 +0000</pubDate><link>https://news.ycombinator.com/item?id=46113778</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=46113778</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=46113778</guid></item><item><title><![CDATA[New comment by chromatin in "How to sequence your DNA for <$2k"]]></title><description><![CDATA[
<p>> Intentionally not bothering to go into why, but above average intelligence.<p>Speaking as a geneticist, it's a shame that this is forbidden knowledge</p>
]]></description><pubDate>Sun, 19 Oct 2025 16:04:14 +0000</pubDate><link>https://news.ycombinator.com/item?id=45635231</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=45635231</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=45635231</guid></item><item><title><![CDATA[New comment by chromatin in "All-New Next Gen of UniFi Storage"]]></title><description><![CDATA[
<p>I've found the same. I've moved from a homebrew tinkerer's delight home network with pfSense running in a VM, Supermicro FreeBSD ZFS fileserver, hodgepodge of cameras etc. to a top-to-bottom Unifi Stack.<p>My time is worth a lot more now, my family appreciates very much that it "Just Works" (tm), and -- most importantly -- the cognitive load for me is a fraction of before.</p>
]]></description><pubDate>Sun, 12 Oct 2025 18:21:49 +0000</pubDate><link>https://news.ycombinator.com/item?id=45560463</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=45560463</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=45560463</guid></item><item><title><![CDATA[New comment by chromatin in "Demand for human radiologists is at an all-time high"]]></title><description><![CDATA[
<p>I am a natural skeptic, but in this case I think it is just an accident of history how different systems developed.<p>FWIW, although this is not well known, many medical schools offer combined BA/MD degrees, ranging from 4-8 years:<p><a href="https://students-residents.aamc.org/medical-school-admission-requirements/medical-schools-offering-combined-baccalaureate-md-programs-state-and-program-length-2024-2025" rel="nofollow">https://students-residents.aamc.org/medical-school-admission...</a><p>When I went 20 years ago, my school did not require a bachelor's degree and would admit exceptional students after 2 years of undergraduate coursework. However I think this has now gone away everywhere due to AAMC criteria</p>
]]></description><pubDate>Fri, 26 Sep 2025 17:34:04 +0000</pubDate><link>https://news.ycombinator.com/item?id=45388988</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=45388988</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=45388988</guid></item><item><title><![CDATA[New comment by chromatin in "Demand for human radiologists is at an all-time high"]]></title><description><![CDATA[
<p>Partially true, and the answer to that is runway -- it will be a very long time before all the other specialties are fully augmented. With respect to "non-surgical" you may be underestimating the number and variety of procedures performed by non-surgeons (e.g. Internal Medicine physicians) -- thyroid biopsy, bronchoscopy, endoscopic retrograde cholangiopancreatography, liquid nitrogen ablation of skin lesion, bone marrow aspiration, etc.<p>The other answer is that AI will not hold your hand in the ICU, or share with you how their mother felt when on the same chemo regimen that you are prescribing.</p>
]]></description><pubDate>Fri, 26 Sep 2025 12:17:23 +0000</pubDate><link>https://news.ycombinator.com/item?id=45385631</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=45385631</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=45385631</guid></item><item><title><![CDATA[New comment by chromatin in "Demand for human radiologists is at an all-time high"]]></title><description><![CDATA[
<p>The belief is -- and it is one that I share -- that this makes for more well rounded, human physicians.<p>Additionally, a greater depth of thinking leads to better diagnosticians, and physician-scientists as well (IMO).<p>Now, all of this is predicated on the traditional model of the University education, not the glorified jobs training program that it has slowly become.</p>
]]></description><pubDate>Fri, 26 Sep 2025 12:12:44 +0000</pubDate><link>https://news.ycombinator.com/item?id=45385593</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=45385593</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=45385593</guid></item><item><title><![CDATA[New comment by chromatin in "Zip Code Map of the United States"]]></title><description><![CDATA[
<p>My ZIP code happens to be shared by two separate cities and there are a few websites (Github, I'm looking at you) that will fail the payment, registration, etc. attempt if you don't enter the municipality that it THINKS is correct.</p>
]]></description><pubDate>Tue, 23 Sep 2025 15:50:45 +0000</pubDate><link>https://news.ycombinator.com/item?id=45348736</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=45348736</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=45348736</guid></item><item><title><![CDATA[New comment by chromatin in "Open models by OpenAI"]]></title><description><![CDATA[
<p>I think his point is that slavery is not outlawed by the 13th amendment as most people assume (even the Google AI summary reads: "The 13th Amendment to the United States Constitution, ratified in 1865, officially abolished slavery and involuntary servitude in the United States.").<p>However, if you actually read it, the 13th amendment makes an explicit allowance for slavery (i.e. expressly allows it):<p>"Neither slavery nor involuntary servitude, *except as a punishment for crime whereof the party shall have been duly convicted*" (emphasis mine obviously since Markdown didn't exist in 1865)</p>
]]></description><pubDate>Tue, 05 Aug 2025 21:39:35 +0000</pubDate><link>https://news.ycombinator.com/item?id=44804715</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=44804715</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=44804715</guid></item><item><title><![CDATA[New comment by chromatin in "Perplexity is using stealth, undeclared crawlers to evade no-crawl directives"]]></title><description><![CDATA[
<p>402 Payment Required<p><a href="https://developer.mozilla.org/en-US/docs/Web/HTTP/Reference/Status/402" rel="nofollow">https://developer.mozilla.org/en-US/docs/Web/HTTP/Reference/...</a><p>Sadly development along these lines has not progressed. Yes, Google Cloud and other services may return it and require some manual human intervention, but I'd love to see _automatic payment negotiation_.<p>I'm hopeful that instant-settlement options like Bitcoin Lightning payments could progress us past this.<p><a href="https://docs.lightning.engineering/the-lightning-network/l402" rel="nofollow">https://docs.lightning.engineering/the-lightning-network/l40...</a><p><a href="https://hackernoon.com/the-resurgence-of-http-402-in-the-age-of-agentic-ai" rel="nofollow">https://hackernoon.com/the-resurgence-of-http-402-in-the-age...</a></p>
]]></description><pubDate>Mon, 04 Aug 2025 17:27:51 +0000</pubDate><link>https://news.ycombinator.com/item?id=44788908</link><dc:creator>chromatin</dc:creator><comments>https://news.ycombinator.com/item?id=44788908</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=44788908</guid></item></channel></rss>