Hacker News: dannykwells

New comment by dannykwells in "Anthropic logged net loss of over $80B in first half of 2026"

dannykwells — Tue, 20 Oct 2026 21:30:51 +0000

From Bloomberg:

The overwhelming majority of the net loss in the first half of this year, $72 billion, resulted from accounting charges linked to changes in the value of convertible notes and other instruments Anthropic has issued, according to the report.

So this is really just capped notes converting. Total nothing burger.

New comment by dannykwells in ""I'm on a war footing": Terry Tao and the crisis in math"

dannykwells — Mon, 19 Oct 2026 02:22:44 +0000

I wish Terry the best.

New comment by dannykwells in "Responsible Release of AI-Generated Mathematics"

dannykwells — Thu, 01 Oct 2026 13:06:41 +0000

This a thousand times. Thank you.

New comment by dannykwells in "The Millennium Problems for Biology"

dannykwells — Mon, 21 Sep 2026 02:51:16 +0000

Also Bingo.

New comment by dannykwells in "The Millennium Problems for Biology"

dannykwells — Mon, 21 Sep 2026 02:50:51 +0000

Bingo.

New comment by dannykwells in "Dario, Please"

dannykwells — Mon, 14 Sep 2026 22:24:31 +0000

Yes exactly!!!

New comment by dannykwells in "David Sacks: OpenAI and Anthropic Don't Need Regulations to Pace Frontier Models"

dannykwells — Sun, 13 Sep 2026 18:19:24 +0000

Bingo. The goal is positioning a duopoly / cartel as the only “safe” and “moral” path and then that cartel sets pace and price.

New comment by dannykwells in "Cruz Enters the 2028 Conversation as Republican Succession Race Takes Shape"

dannykwells — Thu, 03 Sep 2026 08:23:23 +0000

Slop

New comment by dannykwells in "Launch HN: Tamarind Bio (YC W24) – AI Inference Provider for Drug Discovery"

dannykwells — Thu, 08 Jan 2026 15:51:39 +0000

Tamarind is the best! Truly a YC company that provides true, bona fide value to biologists like us. (Hi Sherry!)

New comment by dannykwells in "Lovense: The Company That Lies to Security Researchers"

dannykwells — Tue, 29 Jul 2025 22:21:42 +0000

This is what I come here for.

New comment by dannykwells in "Man wearing metallic necklace dies after being sucked into MRI machine"

dannykwells — Mon, 21 Jul 2025 18:44:23 +0000

A plot line literally out of a Final Destination movie (the newest one). MRI machines are scary!

New comment by dannykwells in "We investigated Amsterdam's attempt to build a 'fair' fraud detection model"

dannykwells — Mon, 16 Jun 2025 04:18:09 +0000

Can someone explain to me - assuming they have enough data - why not train different models explicitly for each group / subgroup you want to model? You even could then just take the top N% of each group by score, effectively guaranteeing equal treatment for each group. Why would this not work?

New comment by dannykwells in "23andMe Sells Gene-Testing Business to DNA Drug Maker Regeneron"

dannykwells — Mon, 19 May 2025 15:49:16 +0000

This is honestly a fantastic outcome.

Regeneron is among the most science and data focused biopharma and has a long, long history in genetics. They know how critical privacy is and will ensure the data are used to advance human health.

Potentially an even better home for the data than in the company, since now will not have pressure of quarterly reports.

New comment by dannykwells in "'Unparalleled' snake antivenom made from man bitten 200 times"

dannykwells — Sat, 03 May 2025 15:04:58 +0000

Absolutely amazing study.

New comment by dannykwells in "You Can't Outrun AI in Tech Interviews, So We Designed Around It"

dannykwells — Fri, 18 Apr 2025 02:53:21 +0000

This.

New comment by dannykwells in "I am rich and have no idea what to do"

dannykwells — Fri, 03 Jan 2025 01:46:54 +0000

Time to find a long term partner and have / adopt / take care of kids.

No joke. I’ve seen it work wonders for providing meaning to many, including multiple rich-beyond-belief founders.

New comment by dannykwells in "Trial results for new lung cancer drug are 'off the charts'"

dannykwells — Fri, 31 May 2024 20:11:23 +0000

Note that this drug is not new - it is fully approved for ALK+ NSCLC and has been since 2015.

It's not clear why these data are just coming out now or what is different from the original trials run in this setting.

https://en.wikipedia.org/wiki/Lorlatinib

New comment by dannykwells in "Trial results for new lung cancer drug are 'off the charts'"

dannykwells — Fri, 31 May 2024 20:09:21 +0000

Durva is starting to show some benefit here.

https://www.cancernetwork.com/view/durvalumab-significantly-...

New comment by dannykwells in "Ask HN: Why don't VCs just "suck it up" and pay founders a competitive salary?"

dannykwells — Tue, 21 May 2024 21:22:39 +0000

Founders can make a "competitive" salary, if they have existing experience for the actual job of being a founder (i.e., previous executive leadership experience).

For many, being a founder is not just "taking a risk on an unproven idea" it's also a career change from being a solo IC or technical leader to being an executive, with very, very different requirements for success, so the risk here is compounded.

New comment by dannykwells in "McKinsey Under Criminal Investigation over Opioid-Related Consulting"

dannykwells — Thu, 25 Apr 2024 01:02:59 +0000

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