On the other hand, Blind Assassin was extremely boring to me until the very last page, but that last page blew my mind.

Comments URL: https://news.ycombinator.com/item?id=49498732

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On the client side, there is usually a local connection pool. When a burst of traffic comes in, the client needs to either wait for the pool to free up or establish a new connection, which adds latency. This latency hit wouldn’t occur with multiplexing.

With multiplexing, systems like pgbouncer would be unnecessary.

Also, even with a thread-per-connection, you can still quickly exhaust the servers resources when you have lots of connections because threads have a lot of overhead. Reducing the number of connections needed would greatly increase the number of clients that a database can serve.

> You may have heard that if you have an MTHFR variant, you should avoid folic acid and should take other types of folate, such as 5-MTHF. However, this is not true. People with an MTHFR gene variant can process all types of folate, including folic acid. Folic acid is the only type of folate shown to help prevent neural tube defects (NTDs).

> A qualified health claim is supported by less scientific evidence than an authorized health claim. FDA requires that qualified claims be accompanied by a disclaimer that explains the level of the scientific evidence supporting the relationship.

> Unlike authorized health claims, FDA does not issue regulations for qualified health claims.

That does seem to indicate supplement manufacturers have broad latitude to make claims provided they are disclosed as such.

We were expanding our product to a new language that used non-ASCII code points. Part of the system involved invoking binaries using text as input.

Locally, everything worked great. Once deployed, we got corrupted text output. As soon as we SSH’d on to the server to inspect, everything started working again.

It turns out that SSH servers can modify the LANG environment variable. The default value on our servers didn’t support Unicode, but LANG was updated as soon as we connected via ssh. It was a head scratcher for sure.