<rss version="2.0" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Hacker News: faangguyindia</title><link>https://news.ycombinator.com/user?id=faangguyindia</link><description>Hacker News RSS</description><docs>https://hnrss.org/</docs><generator>hnrss v2.1.1</generator><lastBuildDate>Sun, 18 Oct 2026 07:50:25 +0000</lastBuildDate><atom:link href="https://hnrss.org/user?id=faangguyindia" rel="self" type="application/rss+xml"></atom:link><item><title><![CDATA[New comment by faangguyindia in "GLP-1 may slow biological aging"]]></title><description><![CDATA[
<p>No, they don't. It's very difficult to have the SAME TDEE even in identical twins, eating the same food and having same activity level.</p>
]]></description><pubDate>Sun, 18 Oct 2026 06:49:13 +0000</pubDate><link>https://news.ycombinator.com/item?id=50138519</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50138519</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50138519</guid></item><item><title><![CDATA[New comment by faangguyindia in "GLP-1 may slow biological aging"]]></title><description><![CDATA[
<p>>This isn't true. Identical people on identical diets will lose the same weight, GLP1 or not.<p>No, this isn't true.<p>Even when two people are identical twins eating the same amount of food and doing the same amount of exercise and activities, weight loss will differ because:<p>Rate of loss of BodyWeight rate is directly proportional to amount of deficit applied!<p>Deficit = TDEE (total calorie burn of the day) - Intake<p>If TDEE is not the same, weight loss will differ, regardless of whether the underlying activity level, genetics, or amount of food or everything else is the same.<p>For more details u can check my post on this:
<a href="https://macrocodex.app/knowledge/macrocodex/smart-calorie-burn-v2/#subproblem-2-is-tdee-fixed-or-predictable" rel="nofollow">https://macrocodex.app/knowledge/macrocodex/smart-calorie-bu...</a><p>>(That part is true.)<p>Improved insulin sensitivity is associated with lower excess body fat THE MOST and better skeletal muscle metabolic function. Greater lean mass may contribute.<p>Therefore, if a person on GLP-1 loses more lean mass than one without, they may not actually have better insulin sensitivity.</p>
]]></description><pubDate>Sun, 18 Oct 2026 05:05:38 +0000</pubDate><link>https://news.ycombinator.com/item?id=50138065</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50138065</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50138065</guid></item><item><title><![CDATA[New comment by faangguyindia in "GLP-1 may slow biological aging"]]></title><description><![CDATA[
<p>>Bruh, we're not doing this anymore. If weight loss was easy, we wouldn't have an adult obesity rate of 40%. Yes, yes, a handful of extraordinarily motivated individuals can successfully restrict calories to lose weight. But very clearly most people can't.<p>I do not agree with this. Those studies being used to push the idea that "diet and exercise failed obese people" are flawed, and I posted a comment on this post explaining all the flaws. You can choose to respond to them instead; I won't copy paste it here.<p>Weight loss requires a calorie deficit, and the average person has no training or education for this. Why would you expect them to be good at something they've had no education or training in? 40% obesity rate is not surprising when no education/training exists for average person.<p>We've already achieved guaranteed results within 2–3 weeks for free (we make no money from this) for all of our users for weight loss or gain, with validation from 17,000+ users for free.<p>If we are just "scammers," how do we make money by pushing this idea?<p>You can read reviews and testimonials from people.<p>The method we use is "slight deficit", see this: <a href="https://macrocodex.app/knowledge/rethink/adaptive-tdee/" rel="nofollow">https://macrocodex.app/knowledge/rethink/adaptive-tdee/</a> (you can find all citation/research being used to achieve this)<p>Our solution is available for free to use!<p>A deficit so small that most users won't even know that they are at deficit!<p>You know that if i remove 150kcal from your diet, your wouldn't notice? that's like 2 slices of bread.  So the hunger suppression will never be a question for vast majority of fat people<p>150kcal deficit over a year = 7.1kg or 15.6 lbs lost! and 300kcal = 31.2lbs or 14.2kg!! all this without any injection or drug without any exercise or severe loss of lean masss<p>>You're conflating association and causality.<p>Same is true when you talk about positives of GLP-1s, most of the benefits actually come from "calorie restriction" and it's very hard to seperate which part comes from where.</p>
]]></description><pubDate>Sun, 18 Oct 2026 04:30:23 +0000</pubDate><link>https://news.ycombinator.com/item?id=50137934</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50137934</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50137934</guid></item><item><title><![CDATA[New comment by faangguyindia in "GLP-1 may slow biological aging"]]></title><description><![CDATA[
<p>People have been claiming similar effects for astrology, alchemy, and other things as well.</p>
]]></description><pubDate>Sun, 18 Oct 2026 03:35:19 +0000</pubDate><link>https://news.ycombinator.com/item?id=50137698</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50137698</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50137698</guid></item><item><title><![CDATA[New comment by faangguyindia in "GLP-1 may slow biological aging"]]></title><description><![CDATA[
<p>People just hold onto their beliefs. GLP-1 believers aren't going to forego their beliefs, even when a large body of evidence is supplied that GLP-1s aren't really necessary for the majority of people.<p>People believe what they want to believe; evidence has little to do with it.<p>They simply assign less weight to evidence that does not meet their "narrative or belief."</p>
]]></description><pubDate>Sun, 18 Oct 2026 03:32:15 +0000</pubDate><link>https://news.ycombinator.com/item?id=50137683</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50137683</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50137683</guid></item><item><title><![CDATA[New comment by faangguyindia in "GLP-1 may slow biological aging"]]></title><description><![CDATA[
<p>People have been achieving far greater rate of weight loss using crash dieting, it's nothing new.<p>You probably lost a major chunk of lean mass if GLP-1 is the only thing you used without much diet changes or exercise.</p>
]]></description><pubDate>Sun, 18 Oct 2026 03:26:46 +0000</pubDate><link>https://news.ycombinator.com/item?id=50137655</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50137655</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50137655</guid></item><item><title><![CDATA[New comment by faangguyindia in "GLP-1 may slow biological aging"]]></title><description><![CDATA[
<p>At the expense of weakened immunity, bone health, muscle wasting, and fertility issues!</p>
]]></description><pubDate>Sun, 18 Oct 2026 03:23:41 +0000</pubDate><link>https://news.ycombinator.com/item?id=50137641</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50137641</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50137641</guid></item><item><title><![CDATA[New comment by faangguyindia in "GLP-1 may slow biological aging"]]></title><description><![CDATA[
<p>Many people don't do their jobs properly. Why should scientists get the benefit of the doubt?<p>If something is true it will survive the scrutiny, requires no appeal to authority.</p>
]]></description><pubDate>Sun, 18 Oct 2026 03:11:29 +0000</pubDate><link>https://news.ycombinator.com/item?id=50137571</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50137571</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50137571</guid></item><item><title><![CDATA[New comment by faangguyindia in "GLP-1 may slow biological aging"]]></title><description><![CDATA[
<p>True, GLP-1 user will have higher loss of lean mass than one who is dieting on calorie deficit and exercise so they'll look more "shrunken raisin" than other.</p>
]]></description><pubDate>Sun, 18 Oct 2026 03:10:41 +0000</pubDate><link>https://news.ycombinator.com/item?id=50137565</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50137565</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50137565</guid></item><item><title><![CDATA[New comment by faangguyindia in "GLP-1 may slow biological aging"]]></title><description><![CDATA[
<p>>There is another plausible causal mechanism: weight gain flowing from hunger/metabolic dysregulation. This dysregulation being caused by some "factor X" which also causes other problems.<p>GLP-1s are being promoted to and used by the general public, who aren't even obese, because GLP boosters push the magical properties of GLP-1s.<p>Even most obese people do not actually need GLP-1s.</p>
]]></description><pubDate>Sun, 18 Oct 2026 03:09:36 +0000</pubDate><link>https://news.ycombinator.com/item?id=50137555</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50137555</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50137555</guid></item><item><title><![CDATA[New comment by faangguyindia in "GLP-1 may slow biological aging"]]></title><description><![CDATA[
<p>>But actually achieving significant weight loss with other therapies is incredibly hard, so I think GLP-1s get some credit here.<p>Citation needed! it's not actually difficult, all you need is calorie deficit and it has been routinely done by bodybuilders, athletes, MMA fighters and movie stars/models and thousands of ordinary members on r/caloriedeficit subreddit or other fitness subs!<p>> Hunger signalling isn't the only thing GLP-1s do, so no, we should not just assume every effect stems from weight loss alone<p>Ofc, they also result in an increased risk of gallbladder stones, bile issues, hair loss, and severe loss of lean mass, and we've got actual studies on this.</p>
]]></description><pubDate>Sun, 18 Oct 2026 03:06:07 +0000</pubDate><link>https://news.ycombinator.com/item?id=50137532</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50137532</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50137532</guid></item><item><title><![CDATA[New comment by faangguyindia in "GLP-1 may slow biological aging"]]></title><description><![CDATA[
<p>Exercise does not result in loss of lean mass unless done at a severe deficit. If someone has a low baseline of lean mass, exercise usually boosts it even when a person is in a deficit, but if they are in a surplus, the lean mass boost is more significant.<p>GLP-1s don't.</p>
]]></description><pubDate>Sun, 18 Oct 2026 02:53:56 +0000</pubDate><link>https://news.ycombinator.com/item?id=50137447</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50137447</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50137447</guid></item><item><title><![CDATA[New comment by faangguyindia in "GLP-1 may slow biological aging"]]></title><description><![CDATA[
<p>It's baffling that so many seemingly intelligent people on Hacker News fall into the GLP-1 booster bandwagon!<p>The studies being used to claim “dieting is not effective for weight loss” and for boosting GLPs are flawed and demonstrate corruption and intellectual dishonesty!<p>GLP-1s are tool like a screwdriver but you do not use one to brush your teeth!<p>They are being over prescribed and abused, resulting in hair loss, bile/gallbladder stone risks, severe loss of lean mass, etc. Studies are already out on this! So why cherry pick satudies only positives of GLP-1s?<p>Many boosters have suffered 1 or many of these and now want others to suffer as well to further GLP-1 research at expense of general public!<p>There is a strong GLP booster group. Most people do not need GLP-1s; all they need is a calorie deficit!<p>The market is filled with "Eat X for weight loss, eat Y for weight gain."<p>The average person actually does not choose the right strategy for weight loss, which is a "calorie deficit."<p>But implementing it is not "EASY" until you understand how expenditure, calorie intake, and weight movement work, which is too much work to understand for an average Joe.<p>But once you understand the "core idea" it becomes very EASY AND SIMPLE!<p>Let's take something as simple as "calorie deficit."<p>Being at a calorie deficit itself requires knowing two things:<p>1. How much you burn in a day (total daily energy expenditure or TDEE)<p>2. How much your intake is for the day<p>Deficit = TDEE - Intake<p>You can do calorie counting for #2. But what can you do for #1?<p>The average guy does not know how to calculate these properly, let alone judge weight movement, which can move a lot in the opposite direction due to water weight fluctuations that can exceed 1 kg+ of movement a day.<p>Even GLP-1 users on Triz subreddit agree with this!
<a href="https://www.reddit.com/r/tirzepatidecompound/comments/1omfgxd/everyone_should_read_this_guide_on_losing_fat/" rel="nofollow">https://www.reddit.com/r/tirzepatidecompound/comments/1omfgx...</a><p>We use neural network to solve #1 problem (solution is given away for free, we make no money!), you can also do it manually using calculation listed here but it won't be as accurate as our neural network!</p>
]]></description><pubDate>Sun, 18 Oct 2026 02:38:36 +0000</pubDate><link>https://news.ycombinator.com/item?id=50137351</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50137351</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50137351</guid></item><item><title><![CDATA[New comment by faangguyindia in "Ask HN: Why people do not want to believe weight loss is possible without GLPs?"]]></title><description><![CDATA[
<p>>I think, generally, that people view your work as BS. And you’re right! There is no rule against promoting your BS.<p>No evidence of this, last post had 28 upvotes.<p>Thread posted by some other guy on reddit:
<a href="https://www.reddit.com/r/tirzepatidecompound/comments/1omfgxd/everyone_should_read_this_guide_on_losing_fat/" rel="nofollow">https://www.reddit.com/r/tirzepatidecompound/comments/1omfgx...</a><p>Many people like it! it has reviews, reddit comments voching for it, it's just some guys on HN who boost GLPs who are involved in flagging.<p>Plenty of reviews posted by established users on Reddit.<p>>You’re not wrong! You’re just an asshole Walter! — The Dude<p>An asshole is someone who claims to read the minds of others and uses this to fit their own narration<p>One day, the world will come to know who is the innovator vs. scammer/asshole.</p>
]]></description><pubDate>Sun, 18 Oct 2026 01:05:58 +0000</pubDate><link>https://news.ycombinator.com/item?id=50136824</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50136824</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50136824</guid></item><item><title><![CDATA[New comment by faangguyindia in "Ask HN: Why people do not want to believe weight loss is possible without GLPs?"]]></title><description><![CDATA[
<p>>What is the guaranty? Do you give the money back? It makes the post even more suspicious. Try to avoid infomercial tone here or it will make people even more suspictious.<p>The app is completely free, and there are no ads.<p>So the most you stand to lose is 2-3 weeks spent using the app!<p>I’m not even promoting myself or my coaching company. If you read privacy policy you can see we do not collect any sensitive info either like name, email, phone number of DOB etc... <a href="https://macrocodex.app/privacy-policy/" rel="nofollow">https://macrocodex.app/privacy-policy/</a><p>>You also can claim whatever you like. Do you have any proof? Reviews and testimonials are not reliable. I assume in general that all of them are fake, in spite your may be real or not.<p>The work is even shared on Reddit by others on GLP-1 subreddits:
<a href="https://www.reddit.com/r/tirzepatidecompound/comments/1omfgxd/everyone_should_read_this_guide_on_losing_fat/" rel="nofollow">https://www.reddit.com/r/tirzepatidecompound/comments/1omfgx...</a><p>>Also, I'm not sure what is the difference with other apps. What does it do? It's like a calorie counter but it interpolates the calories when the user forgets to enter them?<p>It uses a neural network for weight loss and weight gain with very high effectiveness; it’s nearly impossible to fail!<p>All the methods we use are documented here in detail, with links to relevant research; we even provide citations:<p><a href="https://macrocodex.app/knowledge/rethink/adaptive-tdee/" rel="nofollow">https://macrocodex.app/knowledge/rethink/adaptive-tdee/</a><p><a href="https://macrocodex.app/knowledge/macrocodex/smart-calorie-burn-v2/" rel="nofollow">https://macrocodex.app/knowledge/macrocodex/smart-calorie-bu...</a><p><a href="https://macrocodex.app/guides/weight-loss/" rel="nofollow">https://macrocodex.app/guides/weight-loss/</a></p>
]]></description><pubDate>Sun, 18 Oct 2026 01:03:13 +0000</pubDate><link>https://news.ycombinator.com/item?id=50136812</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50136812</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50136812</guid></item><item><title><![CDATA[New comment by faangguyindia in "Ask HN: Why people do not want to believe weight loss is possible without GLPs?"]]></title><description><![CDATA[
<p>My previous post had 28 upvotes; the last post received 3 upvotes and then got flagged.<p>It’s not that people don’t like it, but that GLP boosters are flagging it.<p>Nobody managed to prove that we are wrong or that our method is flawed.<p>To my knowledge, nobody else ever managed to do this; there were always excuses like "genetics or hunger," but anyone who used it got the results, and it's baffling to see GLP boosters have been proven wrong, yet they are not really debating or challenging, but rather flagging the post like a coward. No contest?<p>We managed to produce results in "genetically resistant fat" people within a 2–3-week timeframe!<p>Rather than getting acknowledged that this is possible, we are getting flagged by GLP boosters who want the whole world to be on GLPs.</p>
]]></description><pubDate>Sat, 17 Oct 2026 14:51:05 +0000</pubDate><link>https://news.ycombinator.com/item?id=50131668</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50131668</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50131668</guid></item><item><title><![CDATA[New comment by faangguyindia in "Ask HN: Why people do not want to believe weight loss is possible without GLPs?"]]></title><description><![CDATA[
<p>In my country, there is no requirement to be a medical professional to help people lose or gain weight.<p>The app is completely free, and there are no ads. I’m not even promoting myself or my coaching company. If you read privacy policy you can see we do not collect any sensitive info either like name, email, phone number of DOB etc... <a href="https://macrocodex.app/privacy-policy/" rel="nofollow">https://macrocodex.app/privacy-policy/</a><p>We do not make any money from this.<p>All the methods we use are documented here in detail, with links to relevant research; we even provide citations:<p><a href="https://macrocodex.app/knowledge/rethink/adaptive-tdee/" rel="nofollow">https://macrocodex.app/knowledge/rethink/adaptive-tdee/</a><p><a href="https://macrocodex.app/knowledge/macrocodex/smart-calorie-burn-v2/" rel="nofollow">https://macrocodex.app/knowledge/macrocodex/smart-calorie-bu...</a><p><a href="https://macrocodex.app/guides/weight-loss/" rel="nofollow">https://macrocodex.app/guides/weight-loss/</a><p>And we are not doing anything beyond current medical research. The research already existed and had existed for at least a few decades!<p>So, what is my grift?<p>I believe you are not very educated and are more likely to fall for the “appeal to authority” fallacy on this forum?</p>
]]></description><pubDate>Sat, 17 Oct 2026 14:27:30 +0000</pubDate><link>https://news.ycombinator.com/item?id=50131502</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50131502</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50131502</guid></item><item><title><![CDATA[New comment by faangguyindia in "Ask HN: Why people do not want to believe weight loss is possible without GLPs?"]]></title><description><![CDATA[
<p>Nobody else has achieved guaranteed results in 2–3 weeks for both weight loss and weight gain without any drugs but we guarantee it to every user. 80% people will see results on the very first week<p>We've neural network which predicts maintenance calories to very high accuracy, this has never been done before at this level with thousands of users and so much success!<p>We have enough validation: thousands of users. The app is completely free and not even new; no ads or personal identifying information are collected.<p>What is not to like about this?<p>We are being flagged because GLP boosters on this site do not like that it is possible to lose weight with very little effort without GLPs.</p>
]]></description><pubDate>Sat, 17 Oct 2026 14:22:54 +0000</pubDate><link>https://news.ycombinator.com/item?id=50131448</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50131448</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50131448</guid></item><item><title><![CDATA[New comment by faangguyindia in "Ask HN: Why people do not want to believe weight loss is possible without GLPs?"]]></title><description><![CDATA[
<p>There is no guideline that says you cannot post your project, which received significant upgrades/work, after a few months.</p>
]]></description><pubDate>Sat, 17 Oct 2026 14:13:40 +0000</pubDate><link>https://news.ycombinator.com/item?id=50131373</link><dc:creator>faangguyindia</dc:creator><comments>https://news.ycombinator.com/item?id=50131373</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=50131373</guid></item><item><title><![CDATA[New comment by faangguyindia in "Ask HN: Why people do not want to believe weight loss is possible without GLPs?"]]></title><description><![CDATA[
<p>It's strange, so all the people who are overweight by 5-10kg have hormone imbalance?<p>>Your app isn’t going to fix brain chemistry and a hormone imbalance. It’s snake oil. Are you a medical professional? Show the creds.<p>Read the reviews. If 17,000+ users and all these reviews, guides, and posts on Reddit are not “enough creds,” then what is?<p>I have been a coach for over 10 years.<p>Creator of fitness guides shared across Reddit, like this one on a GLP-1 subreddit
<a href="https://www.reddit.com/r/tirzepatidecompound/comments/1omfgxd/everyone_should_read_this_guide_on_losing_fat/" rel="nofollow">https://www.reddit.com/r/tirzepatidecompound/comments/1omfgx...</a></p>
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