A sizable percentage of autoimmune cases of well accepted autoimmune diseases (rheumatoid arthritis, celiac, etc etc etc ) are completely seronegative despite glaringly obvious clinical signs: eg peeing skin, deformed joints etc etc - all blood work perfectly normal. Happens all the time.

Why would we expect anything different here?

Widespread issues all over the body without readily obvious organ damage is nearly always nerves/brain.

99% of physicians wouldn’t know what to do with specialized test results anyway, even if they’d know what/how to order in the first place. Internists don’t know how to read PET scans, radiologists don’t know anything about homeostasis. general radiology cant even read head&neck scans, you want a specialized radiologist for that. geneticists don’t have the slightest idea about how to read nerve studies, which is actually a completely separate certification, not even every neurologist has it or does them.

Medicine is the game of super-specialization.

And nobody wants to bother to try to piece it all together for you. Very few MDs are actually able to, in the first place.

Ideally, you have a very broadly competent internist to figure out what direction to even start digging at, and then find the sub specialist who has the expertise AND interest in that area.

eg NIH’s section on neuro cardiology recently closed because this one dude who was REALLY into simply was too old, couldnt find a replacement or build a bigger lab that could sustain itself and retired.

At times you need a specialist trained and practicing in two different specialties: eg ENT + neuro, for example. Those can be hard to find. Neuro cardio more common especially now.

If you sleep over 11 hrs per 24 hours: that’s pathological and they will be prescribed.

Fall asleep faster than X minutes? Same diagnosis, same meds.

Have apnea and yet still fatigued/sleepy after CPAP/surgery? Same meds.

Fulfill criteria for ADHD? Same meds.

Fatigue after TBI? Same meds.

Fatigue with MS? Same meds.

The root cause may or may not be eventually found, but there is no reason to get diagnosed with whatever is most useful to begin at least supporting treatment.

Nostr zaps?

Amazing. How was that solved in practice?

For residency, the two most important things are: 1) board scores. 2) research output.

It's not uncommon to see 40-50 publications for competitive residencies.

incentives, incentives, incentives.

post-viral syndromes have been with us for a long time.

outside of very clear sequelae like definitive texbook case of autoimmune disease or something obvious like that - we don't really know how to treat them?

way worse than PLA.

what's hypnosis porn?

Prediction: just like with anything controversial (like GMOs in Europe, etc etc), it'll be labeled in a way that obfuscates the actual ingredient as not to jeopardize the all-important profits.

First hit on google: https://chapul.com/blogs/chapul-bars-latest-news/what-happen...

"What happens when Western food marketers blend novel food items, such as insect protein, with more commonly accepted ingredients? A recent study suggests that may be an effective strategy."

"no value" here is probably in tens, maybe hundreds of trillions of dollars in the present time PPP basis.

I also wonder why not use use the domain, much easier.

https://news.ycombinator.com/item?id=32580631#32588473