<rss version="2.0" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Hacker News: jmcgough</title><link>https://news.ycombinator.com/user?id=jmcgough</link><description>Hacker News RSS</description><docs>https://hnrss.org/</docs><generator>hnrss v2.1.1</generator><lastBuildDate>Mon, 15 Jun 2026 02:35:09 +0000</lastBuildDate><atom:link href="https://hnrss.org/user?id=jmcgough" rel="self" type="application/rss+xml"></atom:link><item><title><![CDATA[New comment by jmcgough in "New pancreatic cancer drug might open the door to much longer survival times"]]></title><description><![CDATA[
<p>They influence clinical decisions by adding to treatment options, but they do not make clinical decisions. If we believe that a drug's potential risks outweigh its benefits, clinicians will not prescribe it.</p>
]]></description><pubDate>Sun, 14 Jun 2026 14:45:29 +0000</pubDate><link>https://news.ycombinator.com/item?id=48527713</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=48527713</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48527713</guid></item><item><title><![CDATA[New comment by jmcgough in "New pancreatic cancer drug might open the door to much longer survival times"]]></title><description><![CDATA[
<p>I can understand being frustrated and cynical with the pharmaceutical industry, but I have never worked with a single doctor that approaches patient care with the goal of getting them "hooked" on something for life.<p>The pharmaceutical companies are not the ones making clinical decisions - in this case, it's a shared medical decision between a patient and their oncologist.<p>Having seen how horrific pancreatic cancer is, how difficult it is to treat, and the decades of slow research done by academic scientists to get to this point, I am elated that we have a tool to give patients more time with their families even if their cancer can't be "cured" with this particular drug.<p>This may seem unsatisfying, but it's real, measurable progress. KRAS has been known about since the earliest days of cancer research, so it's a true breakthrough to finally have a drug targeting it.</p>
]]></description><pubDate>Sun, 14 Jun 2026 00:23:06 +0000</pubDate><link>https://news.ycombinator.com/item?id=48522905</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=48522905</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48522905</guid></item><item><title><![CDATA[New comment by jmcgough in "Bricks and Minifigs Stole a Man's $200k Lego Collection"]]></title><description><![CDATA[
<p>I have a family member who works in estate planning. From all the stories he's told me, a lot of wealthy people compulsively screw over people / refuse to follow the contract they agreed to / etc, simply because they can and know that it is too expensive for most people to file a lawsuit.</p>
]]></description><pubDate>Fri, 29 May 2026 06:44:10 +0000</pubDate><link>https://news.ycombinator.com/item?id=48319849</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=48319849</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48319849</guid></item><item><title><![CDATA[New comment by jmcgough in "ICE Awards $25M Iris-Scanning Contract to Bi2 Technologies"]]></title><description><![CDATA[
<p>How do we know there's any plan to accomplish this, and that this isn't just funneling $25M to a family member?</p>
]]></description><pubDate>Sun, 24 May 2026 02:25:48 +0000</pubDate><link>https://news.ycombinator.com/item?id=48253737</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=48253737</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48253737</guid></item><item><title><![CDATA[New comment by jmcgough in "ICE Awards $25M Iris-Scanning Contract to Bi2 Technologies"]]></title><description><![CDATA[
<p>They aren't interested in those responsibilities, just enriching themselves and attacking their enemies.</p>
]]></description><pubDate>Sun, 24 May 2026 02:24:18 +0000</pubDate><link>https://news.ycombinator.com/item?id=48253725</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=48253725</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48253725</guid></item><item><title><![CDATA[New comment by jmcgough in "Meta deletes popular 1M follower account after Kuwaiti request"]]></title><description><![CDATA[
<p>The American right to free speech has never extended to fomenting an armed mob and directing them to commit criminal acts.</p>
]]></description><pubDate>Sun, 17 May 2026 20:53:08 +0000</pubDate><link>https://news.ycombinator.com/item?id=48173093</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=48173093</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48173093</guid></item><item><title><![CDATA[New comment by jmcgough in "Preserving Fisher-Price Pixter"]]></title><description><![CDATA[
<p>Took two minutes of reading his Twitter to find him comparing black people to chimpanzees.</p>
]]></description><pubDate>Wed, 13 May 2026 15:31:39 +0000</pubDate><link>https://news.ycombinator.com/item?id=48123253</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=48123253</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48123253</guid></item><item><title><![CDATA[New comment by jmcgough in "OpenAI’s o1 correctly diagnosed 67% of ER patients vs. 50-55% by triage doctors"]]></title><description><![CDATA[
<p>LLMs can be a useful second opinion for a highly educated patient with good insight into their health and body, but this is not the average patient I see in an urban emergency department. Many patients can't give a cohesive history without a skilled clinician who can ask the right questions and read between the lines.<p>I am very skeptical of studies like this that don't adequately reflect real world conditions, but when I was a software engineer I probably wouldn't have understood what "real" medicine is like either.</p>
]]></description><pubDate>Sun, 03 May 2026 20:54:34 +0000</pubDate><link>https://news.ycombinator.com/item?id=48001370</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=48001370</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48001370</guid></item><item><title><![CDATA[New comment by jmcgough in "When Dawkins met Claude – Could this AI be conscious?"]]></title><description><![CDATA[
<p>We don't really have a good way to measure whether something has consciousness. Heck, we have pretty limited ways of testing how "intelligent" non-human animals are (e.g. <a href="https://en.wikipedia.org/wiki/Theory_of_mind_in_animals" rel="nofollow">https://en.wikipedia.org/wiki/Theory_of_mind_in_animals</a>).<p>With that said, just because we don't have a great way of measuring it doesn't mean that we should assume LLMs are intelligent. An LLM is code and a massive collection of training weights. It has no means of observing and reasoning about the world, doesn't store memories the same way that organic brains do (and is in fact quite limited in this aspect). It currently isn't able to solve a problem it hasn't encountered in its training data, or produce novel research on a topic without significant handholding. Furthermore, the frequent errors made by it suggests that it fundamentally does not understand the words that it spits out.<p>Not really sure what you mean by your anesthesiology comment. Being able to intubate and inject propofol does not make you more of an expert on consciousness than neuroscientists and neurologists.</p>
]]></description><pubDate>Sun, 03 May 2026 09:34:56 +0000</pubDate><link>https://news.ycombinator.com/item?id=47995186</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=47995186</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47995186</guid></item><item><title><![CDATA[New comment by jmcgough in "America's Expanding Domestic Surveillance"]]></title><description><![CDATA[
<p>Doubtful, it's never really deemed worth LEOs time to pursue bike thieves.</p>
]]></description><pubDate>Sat, 02 May 2026 16:46:10 +0000</pubDate><link>https://news.ycombinator.com/item?id=47987999</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=47987999</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47987999</guid></item><item><title><![CDATA[New comment by jmcgough in "If America's so rich, how'd it get so sad?"]]></title><description><![CDATA[
<p>COVID almost certainly had something to do with it, but the US isn't the only country that faced lockdowns, nor is it the only country that experienced inflation. Why is it that most other countries' happiness scores have returned to near-baseline since then, while the US is still so much lower?</p>
]]></description><pubDate>Thu, 23 Apr 2026 19:22:09 +0000</pubDate><link>https://news.ycombinator.com/item?id=47880380</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=47880380</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47880380</guid></item><item><title><![CDATA[New comment by jmcgough in "We gave an AI a 3 year retail lease and asked it to make a profit"]]></title><description><![CDATA[
<p>A lot of things it could be a direct reference to, but the obvious one is Palantir, which is named after the seeing stones used to spy on people by evil antagonists in Lord of the Rings.</p>
]]></description><pubDate>Fri, 17 Apr 2026 02:48:24 +0000</pubDate><link>https://news.ycombinator.com/item?id=47801974</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=47801974</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47801974</guid></item><item><title><![CDATA[New comment by jmcgough in "Playdate’s handheld changed how Duke University teaches game design"]]></title><description><![CDATA[
<p>Panic had a booth at Portland Retro Gaming Expo last year, they were super nice and the Playdates were a lot of fun to play with. Nice to see that people are continuing to enjoy the console, the production process seemed like a nightmare.</p>
]]></description><pubDate>Fri, 17 Apr 2026 02:39:07 +0000</pubDate><link>https://news.ycombinator.com/item?id=47801938</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=47801938</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47801938</guid></item><item><title><![CDATA[New comment by jmcgough in "We gave an AI a 3 year retail lease and asked it to make a profit"]]></title><description><![CDATA[
<p>I can't believe you made a throwaway to pretend to be a HN commenter just to defend your AI store. This is like Scott Adams behavior.</p>
]]></description><pubDate>Thu, 16 Apr 2026 19:17:52 +0000</pubDate><link>https://news.ycombinator.com/item?id=47798164</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=47798164</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47798164</guid></item><item><title><![CDATA[New comment by jmcgough in "We gave an AI a 3 year retail lease and asked it to make a profit"]]></title><description><![CDATA[
<p>Interesting that you made an account just to comment on this and seem to have "heard" a lot of things about this place.</p>
]]></description><pubDate>Thu, 16 Apr 2026 19:12:06 +0000</pubDate><link>https://news.ycombinator.com/item?id=47798092</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=47798092</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47798092</guid></item><item><title><![CDATA[New comment by jmcgough in "We gave an AI a 3 year retail lease and asked it to make a profit"]]></title><description><![CDATA[
<p>Ugh, of course it's written by an AI, which means it's inherently not trustworthy.</p>
]]></description><pubDate>Thu, 16 Apr 2026 19:02:22 +0000</pubDate><link>https://news.ycombinator.com/item?id=47797938</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=47797938</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47797938</guid></item><item><title><![CDATA[New comment by jmcgough in "We gave an AI a 3 year retail lease and asked it to make a profit"]]></title><description><![CDATA[
<p>"Thanks, I hate it"</p>
]]></description><pubDate>Thu, 16 Apr 2026 18:59:32 +0000</pubDate><link>https://news.ycombinator.com/item?id=47797904</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=47797904</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47797904</guid></item><item><title><![CDATA[New comment by jmcgough in "Cal.com is going closed source"]]></title><description><![CDATA[
<p>idk my mom still pays for her aol email account</p>
]]></description><pubDate>Thu, 16 Apr 2026 08:22:47 +0000</pubDate><link>https://news.ycombinator.com/item?id=47790203</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=47790203</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47790203</guid></item><item><title><![CDATA[New comment by jmcgough in "The buns in McDonald's Japan's burger photos are all slightly askew"]]></title><description><![CDATA[
<p>It isn't showing anything that would otherwise be hidden, I think this is a stylistic decision. Looks cute and more natural to me.</p>
]]></description><pubDate>Wed, 15 Apr 2026 22:25:13 +0000</pubDate><link>https://news.ycombinator.com/item?id=47786136</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=47786136</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47786136</guid></item><item><title><![CDATA[New comment by jmcgough in "Live Nation illegally monopolized ticketing market, jury finds"]]></title><description><![CDATA[
<p>Bribes, campaign donations, presidential ballrooms. The current administration has settled MANY cases that they'd already won, it's very easy to buy favors now.</p>
]]></description><pubDate>Wed, 15 Apr 2026 20:04:32 +0000</pubDate><link>https://news.ycombinator.com/item?id=47784501</link><dc:creator>jmcgough</dc:creator><comments>https://news.ycombinator.com/item?id=47784501</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47784501</guid></item></channel></rss>