Hacker News: jtc331

Higher semaglutide dose associated with lower psych events ind. of weight loss

jtc331 — Sat, 05 Sep 2026 22:24:41 +0000

Article URL: https://www.nature.com/articles/s44324-026-00131-3

Comments URL: https://news.ycombinator.com/item?id=49581292

Points: 1

# Comments: 0

New comment by jtc331 in "When "no healthy upstream" isn't about the upstream you think"

jtc331 — Wed, 05 Aug 2026 18:10:49 +0000

Couldn’t even be bothered to disguise LLM generated content.

Painful to read.

New comment by jtc331 in "Fecal transplants for autism deliver success in clinical trials (2019)"

jtc331 — Sat, 16 May 2026 15:55:35 +0000

Given there are cases of sudden onset autism being resolved with antifungals, it’s at least not implausible that fecal transplants could be effective too.

New comment by jtc331 in "Fecal transplants for autism deliver success in clinical trials (2019)"

jtc331 — Sat, 16 May 2026 15:52:15 +0000

There’s some research on sudden onset autism being treated with antifungals; so at least sometimes a sudden change may be the result of something very specific in the gut.

New comment by jtc331 in "Start your meetings at 5 minutes past"

jtc331 — Sat, 10 Jan 2026 12:05:13 +0000

“More social pressure to stop at the top of the hour.”

False.

This doesn’t work.

Source: a company doing this. Meetings just continue on to the 5 after mark.

New comment by jtc331 in "Betty Crocker broke recipes by shrinking boxes"

jtc331 — Mon, 15 Sep 2025 00:23:54 +0000

Brown sugar should be packed; flour must not be — you’ll get substantially more mass per volume than the recipes assume.

New comment by jtc331 in "Scamlexity: When agentic AI browsers get scammed"

jtc331 — Mon, 25 Aug 2025 10:59:46 +0000

I appreciate that the article correctly points out the core design flaw here of LLMs is the non-distinction between content and commands in prompts.

It’s unclear to me if it’s possible to significantly rethink the models to split those, but it seems that that is a minimal requirement to address the issue holistically.

New comment by jtc331 in "Ubiquiti launches UniFi OS Server for self-hosting"

jtc331 — Thu, 31 Jul 2025 18:46:58 +0000

VLAN with an id of 0 isn't possible on the new interface last I checked. Which, granted is a weird thing to do, but...

New comment by jtc331 in "Why does the U.S. always run a trade deficit?"

jtc331 — Tue, 20 May 2025 14:35:51 +0000

The obsession has at least one interesting question attached: ownership of real property. At the limit, at least, that becomes a genuinely interesting question.

New comment by jtc331 in "How much do you think it costs to make a pair of Nike shoes in Asia?"

jtc331 — Thu, 10 Apr 2025 01:11:33 +0000

That assumes that China’s population doesn’t collapse, which mathematically seems quite likely (and it’s already declining).

New comment by jtc331 in ""Ensuring Accountability for All Agencies" – Executive Order"

jtc331 — Thu, 20 Feb 2025 00:59:13 +0000

> What problem, other than judicial review, does it solve for the executive branch?

It’s fairly obvious on its face the concern of the EO is not judicial review but about agencies that nominally are past of the branch the President heads determining interpretations of law contrary to what the head of the executive desires.

And, it does genuinely seem weird to have an executive branch where the head of that branch doesn’t actually control things.

The negative reaction is entirely because of the current executive head, but no one would bat an eye if this were Barack Obama reigning in some executive agency interpreting, say, immigration law in opposition to DACA.

New comment by jtc331 in "Cheap blood test detects pancreatic cancer before it spreads"

jtc331 — Thu, 13 Feb 2025 18:18:16 +0000

For example you might do surgery on people who wouldn’t benefit.

New comment by jtc331 in "CIA now favors lab leak theory to explain Covid's origins"

jtc331 — Sun, 26 Jan 2025 01:58:18 +0000

The problem is that the two theories can have competing indications as to how to prepare. Specifically: should we do gain of function research, or is that foolish — depends on how you read what happened in 2020.

New comment by jtc331 in "Type 2 Diabetes and cardiovascular disease attributable to sugar beverages"

jtc331 — Wed, 08 Jan 2025 03:22:35 +0000

I believe sucrose and fructose are processed differently — specifically fructose is processed by the liver so can have the same issues as alcohol there.

New comment by jtc331 in "Huge math error corrected in black plastic study; authors say it doesn't matter"

jtc331 — Fri, 20 Dec 2024 13:55:48 +0000

At minimum it changes the urgency for individuals with existing cookware.

New comment by jtc331 in "Ticketmaster’s attempt to game arbitration services fails"

jtc331 — Sun, 10 Nov 2024 12:25:41 +0000

Civil suits _do_ have jury trials. They’re even conducted with a lower standard of burden of proof, which is good or bad depending on if you’re potentially getting ramrodded or potentially finally past the Big CO’s lawyers.

New comment by jtc331 in "Medical student's apparent celiac disease responded to giardiasis treatment"

jtc331 — Thu, 17 Oct 2024 01:03:53 +0000

See my comment here: https://news.ycombinator.com/item?id=41865429

New comment by jtc331 in "Medical student's apparent celiac disease responded to giardiasis treatment"

jtc331 — Thu, 17 Oct 2024 01:01:12 +0000

Have you looked into Mutaflor probiotics? It’s a beneficial E. Coli (seriously) that has research showing it can colonize the gut and clinically improve e.g. IBS symptoms. I’ve personally seen it solve (or significantly mitigate) issues for multiple people.

New comment by jtc331 in "Hell Freezes Over as AMD and Intel Come Together for x86"

jtc331 — Wed, 16 Oct 2024 15:14:49 +0000

Graviton single thread performance is _not_ the same as the Intel or AMD offerings on AWS.

What a circle around Paris looks like, according to Mr. Mercator

jtc331 — Sat, 12 Oct 2024 11:30:06 +0000

Article URL: https://old.reddit.com/r/geography/comments/18d8w5b/what_a_circle_around_paris_looks_like_according/

Comments URL: https://news.ycombinator.com/item?id=41818342

Points: 4

# Comments: 0