> And even high quality daycares might not help children potty train

Definitely. I think that's pretty rare.

How many kids nowadays are in daycare?

When there is a 3-to-1 adult-to-child ratio, doing something like this is much more challenging when there's just one adult and one infant.

Example: https://www.diaperstork.com

Then I tried Kagi, and I find that works the majority of the time, including their AI. Someone else in the comments here said Kagi's AI models are bad, but I don't think they are for answering the fairly basic questions that I typically search. I'm not going to have Kagi's AI model refactor code or something though.

Not every company can be an expert at everything.

But perhaps many of us could buy a different CDN than the major players if we want to reduce the likelihood of mass outages like this though.

Depends what you mean by window manager, but an app like Magnet does not require disabling security settings.

https://apps.apple.com/us/app/magnet/id441258766?mt=12

So yes, scale back your purchasing, but as you said: the options are limited, just like political candidates. Choose who matches up best with you, support them, but unlike your relationship to Apple, political participation has a VERY different piece.

You can't just show up and start influencing policy at Apple headquarters.

But you CAN just show up to some local organizing meetings of local grassroots organizations and political parties and influence things. You can have a direct impact, and these groups are usually small enough with few enough participants in your town that you WILL have a decent impact.

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If you're not in step with where you're at, and you can find other employment where you'll be happier, why not change?

You could apply your same logic to, "If you're in a relationship with a significant other, don't break up with them... get them to break up with you! You will absolve yourself of any regrets of dumping them." Yes, and you will have wasted both your time, and their time.

And the same goes for working at a company that you feel isn't good for you.

And if the companies who produce these chips continue to make a healthy profit, why would they stop?

If the chips are cheap and easily available, and you know their failure modes, and they've been field tested for decades, why change?

It's very different from many software development attitudes, but remember that airframe manufacturers and avionics companies employ many people just to calculate risk and failure rates. The failure rates of these things are critical to the safety of your airframe.

But I suspect that won't happen.

1. https://www.transportation.gov/airconsumer/airline-cancellat...

If we're trying to figure out what the most benefit for each taxpayer dollar is, then a rare disease won't win out over, say, cancer research.

Someone may consider researching a rare disease as "waste," even though to everyone including the previous poster who is a widow because of HD, it is far from a waste.

When there is not much of a profit motive to do something - whether going to the moon or fighting a rare disease - public money is the best way to do it. And even throwing a fairly small percentage at it can create big achievements.

And that's one reason I'd like to see how much money and time went into this. We might be surprised that it's fairly small in the grand scheme of biomedical research costs!

I don't ask to strictly bring up politics, but instead to try and address the broad lack of understanding of how medical breakthroughs like this are made.

It's not done just by drug companies. The article says:

> UniQure says it will apply for a licence in the US in the first quarter of 2026 with the aim of launching the drug later that year.

That's true, but that doesn't talk about the tens to hundreds of research papers that have been published over likely decades to make this discovery a reality. And it doesn't talk about how much public money went into this discovery.

Many people reading this article probably have a vague idea that more than just this company was involved, but I feel it is not at all clear to the vast majority of people, since the vast majority of people are not involved in biomedical research.

I wish there was an easy way to figure out how many dollars, how many grants, how many researchers, went into achieving this breakthrough. And that the media would put that into news articles like this. Trace all the citations back a few orders, and I bet you'll find a massive number of NIH and NIHR grants.

There is unfortunately not more massive, bipartisan public outcry in the US over defunding the essential basic research the NIH does... and it's not new to the current administration, since it was attempted to be done back in 2017, too [1].

Scientists need better messaging or else we're going to stop having breakthroughs like this... and the breakthroughs are already going to slow down thanks to things like the $783 million in cuts to NIH grants that the US SCOTUS authorized in August [2].

1. https://pmc.ncbi.nlm.nih.gov/articles/PMC5468112/

2. https://www.scotusblog.com/2025/08/supreme-court-allows-trum...

I started by reading the GTD book, and then tried lots of different apps, but Things for Mac by Cultured Code requires the least work and conforms roughly to the GTD approach. I don't use the strict GTD approach, but its approach to quickly writing down ideas and thoughts has shaped a lot of how I operate at work and even in my personal life.

I sure don't work for anything close to Wired or their parent organization, but if you want good journalism, support it with your dollars. A year's subscription is less than a nice dinner out (or even a not-so-nice dinner out!).

As this article points out, online public posting is performative.

Like the management guidance that is unfortunately not at all practiced enough, "praise publicly, criticize privately."

If you're going to get into a situation where criticism is unavoidable, do it when the person's "punishment" of the criticism won't be public to be read forever and ever.

Plus, it's a lot harder to have zero empathy with someone whose eyes you are looking into, whose presence is right next to you. But an anonymous internet poster, or even identified internet poster who you won't see for months or years? A lot of people don't care about that person's feelings at all, and don't have the leaps of imagination that what they type might actually cause that person pain / tears / sadness / etc.

After a two hour session on my TV, I had to stop due to motion sickness, and I haven’t picked it back up since. Was really fun though.