Using bricks other than 2x2 and 2x4 blocks creatively to make interesting things is really important, i’m not sure what type if algorithm would best auto generate beautiful MOCs however? Was thinking of doing a $50000 kaggle comp for this, what do others think?

We mostly use propofol/remifent for maintenance of anaesthesia, and there is (some) reasonable evidence that this leads to less emergence delirium than sevoflurane. We use EEG-like monitors in all paralysed patients over a few months old.

Annoyingly I can’t access the full study, but would be interested to know why the kids in the low sevoflurane use group weren’t moving or coughing with surgical stimulation. The commonly used doses of sevoflurane are used because they are supposed to inhibit movement in response to noxious stimulus. So presumably these patients are all being paralysed or given a lot of opioid to stop them moving?

Using sevoflurane instead of propofol for maintenance if you are trying to reduce PAED is not really standard of care and makes me suspicious they are trying to overstate the effectiveness of their device.

Call it charity or call it buying gal-pals with hubby’s money but primarily investing based on identity seems like a bad idea

Sadly noone has done this because the topic is too radioactive for most researchers or science funders to touch.

Sorry but this reddit consensus is out of step with actual researchers. The #1 paediatric journal has published quite a bit on this recently. Basically the evidence isn’t of high quality but what we have doesn’t look great.

https://jamanetwork.com/journals/jamapediatrics/fullarticle/...