Hacker News: maxall4

NIH restrictions on foreign research partnerships impacted 1 in 4 scientists

maxall4 — Thu, 02 Apr 2026 23:50:14 +0000

Article URL: https://www.statnews.com/2026/03/27/nih-funding-national-researcher-survey-foreign-subaward-ban-impact/

Comments URL: https://news.ycombinator.com/item?id=47621715

Points: 4

# Comments: 0

New comment by maxall4 in "Multiple Sclerosis"

maxall4 — Tue, 31 Mar 2026 15:45:15 +0000

I was part of a team researching MS at a university a while ago. It truly is an endlessly fascinating disease. Most evidence currently points to MS being caused by a combination of Epstein-Barr infection and genetic factors [0,1]. It is hypothesized that Epstein-Barr triggers autoimmunity which results in the prototypical demyelination [2].

[0]: https://www.science.org/doi/10.1126/science.abj8222

[1]: https://www.pnas.org/doi/10.1073/pnas.2424986122

[2]: https://www.nature.com/articles/s41586-022-04432-7

Verquotrine – Short Story [pdf]

maxall4 — Sun, 22 Mar 2026 02:02:01 +0000

Article URL: https://static1.squarespace.com/static/686d9fb49c4cda307c6a05e4/t/68b134adddc0cf4e1869bf32/1756443821834/Verquotrine+Final.pdf

Comments URL: https://news.ycombinator.com/item?id=47473698

Points: 1

# Comments: 0

An Australian man, using ChatGPT, made an mRNA vaccine to treat his dog's cancer

maxall4 — Sun, 15 Mar 2026 16:55:42 +0000

Article URL: https://www.dawn.com/news/1982334

Comments URL: https://news.ycombinator.com/item?id=47389234

Points: 4

# Comments: 2

New comment by maxall4 in "Enhancing gut-brain communication reversed cognitive decline in aging mice"

maxall4 — Thu, 12 Mar 2026 17:52:33 +0000

I smell bad data. This sounds too good to be true and most studies of this kind have turned out to be false a few years down the line.

Edit: one of many examples: https://www.science.org/content/article/journal-retracts-inf...

New comment by maxall4 in "Gemini 3.1 Pro"

maxall4 — Thu, 19 Feb 2026 16:52:23 +0000

Theoretically, you can’t benchmaxx ARC-AGI, but I too am suspect of such a large improvement, especially since the improvement on other benchmarks is not of the same order.

New comment by maxall4 in "A Broken Heart"

maxall4 — Thu, 05 Feb 2026 16:48:37 +0000

I think you could have discovered this bug more easily by looking at the commit(s) that were made when the problem started.

Reputation (FDA's Version)

maxall4 — Sun, 18 Jan 2026 17:32:41 +0000

Article URL: https://asteriskmag.com/issues/12-books/reputation-fdas-version

Comments URL: https://news.ycombinator.com/item?id=46669937

Points: 2

# Comments: 0

Sins of the Children

maxall4 — Sun, 18 Jan 2026 17:08:58 +0000

Article URL: https://asteriskmag.com/issues/07/sins-of-the-children

Comments URL: https://news.ycombinator.com/item?id=46669663

Points: 190

# Comments: 88

New comment by maxall4 in "We put Claude Code in Rollercoaster Tycoon"

maxall4 — Sun, 18 Jan 2026 00:20:02 +0000

> In this article we'll tell you why we decided to put Claude Code into RollerCoaster Tycoon, and what lessons it taught us about B2B SaaS.

What is this? A LinkedIn post?

New comment by maxall4 in "Iran Goes Into IPv6 Blackout"

maxall4 — Thu, 08 Jan 2026 19:37:12 +0000

Starlink receivers are actually very complicated. They make use of a bunch of high-end FPGAs and a bunch of other expensive and uncommon components. See this teardown: https://youtu.be/h6MfM8EFkGg?si=m-sN6UW4nh8_HzPR.

Trump calls for record $1.5T defense budget, a 50 percent jump

maxall4 — Thu, 08 Jan 2026 00:12:23 +0000

Article URL: https://www.politico.com/news/2026/01/07/trump-calls-record-defense-budget-00715298

Comments URL: https://news.ycombinator.com/item?id=46535212

Points: 16

# Comments: 6

New comment by maxall4 in "ManusAI Joins Meta"

maxall4 — Tue, 30 Dec 2025 08:21:20 +0000

If I read one more article/press release/whatever with such clumsy use of antithesis, I’m going to go insane. I have no problem with using AI to write if it is done well, but this…

New comment by maxall4 in "Show HN: No more writing shitty regexes to police usernames"

maxall4 — Wed, 24 Dec 2025 18:02:05 +0000

Sure, but I’m not convinced that producing a blacklist and filtering system is that difficult. More importantly, it’s little things like this that slowly and insidiously degrade the user experience. Sure it starts with one 300ms API call, maybe most people won’t notice. But when you reach for solutions like this to every minor technical problem, the next thing you know it takes 5 seconds to sign-up.

New comment by maxall4 in "Show HN: No more writing shitty regexes to police usernames"

maxall4 — Wed, 24 Dec 2025 17:53:40 +0000

I can’t tell if this is some complex joke or a real product. This is literally string.contains() as a service.

Edit: 300ms?!

New comment by maxall4 in "Fuck You, I Won't Use Tailwind"

maxall4 — Tue, 23 Dec 2025 21:19:09 +0000

The problem with HTML and CSS is there are encapsulation boundaries where there shouldn’t be. Tailwind, by contrast, does not separate the layout from the styling; creating a more cohesive developer experience. Anyone making a point like this does not understand why Tailwind—and similar libraries—are superior to classical encapsulated HTML/CSS.