<rss version="2.0" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Hacker News: new299</title><link>https://news.ycombinator.com/user?id=new299</link><description>Hacker News RSS</description><docs>https://hnrss.org/</docs><generator>hnrss v2.1.1</generator><lastBuildDate>Sun, 11 Oct 2026 02:35:20 +0000</lastBuildDate><atom:link href="https://hnrss.org/user?id=new299" rel="self" type="application/rss+xml"></atom:link><item><title><![CDATA[BillionToOne IPO]]></title><description><![CDATA[
<p>Article URL: <a href="https://aseq.substack.com/p/billiontoone-ipo">https://aseq.substack.com/p/billiontoone-ipo</a></p>
<p>Comments URL: <a href="https://news.ycombinator.com/item?id=45554370">https://news.ycombinator.com/item?id=45554370</a></p>
<p>Points: 1</p>
<p># Comments: 0</p>
]]></description><pubDate>Sun, 12 Oct 2025 01:37:49 +0000</pubDate><link>https://aseq.substack.com/p/billiontoone-ipo</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=45554370</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=45554370</guid></item><item><title><![CDATA[New comment by new299 in "Solving `Passport Application` with Haskell"]]></title><description><![CDATA[
<p>Parent of applicant but not grandparents, at least in my case.</p>
]]></description><pubDate>Sun, 29 Jun 2025 11:11:05 +0000</pubDate><link>https://news.ycombinator.com/item?id=44412141</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=44412141</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=44412141</guid></item><item><title><![CDATA[New comment by new299 in "Solving `Passport Application` with Haskell"]]></title><description><![CDATA[
<p>:(<p>Weirdly this never came up for me (and I'm in a similar situation). I suspect what documents are ask for varies a lot by who is assessing the application.<p>Hope it all works out!</p>
]]></description><pubDate>Sun, 29 Jun 2025 11:09:39 +0000</pubDate><link>https://news.ycombinator.com/item?id=44412133</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=44412133</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=44412133</guid></item><item><title><![CDATA[New comment by new299 in "Solving `Passport Application` with Haskell"]]></title><description><![CDATA[
<p>For the benefit of anyone else doing this in Japan, these are the documents I had to submit. It will be different depending on circumstance, in particular I think the author may also be born outside the UK which may require other/more documents.<p>Anyway I had to submit:<p>Certified copy of my birth certificate, order from the UK general register office.<p>Original (not photocopy) of Japanese family register and translation.<p>Certificate of acceptance of notification of birth, original and translation.<p>Original Marriage certificate and translation.<p>Colour photocopy of every page of my childs Japanese passport.<p>Copy photocopy of the passport of an American or British citizen who confirms that child is mine.<p>The process is pretty unclear, and in general you seem to have to just keep submitting documents until they are satisfied.</p>
]]></description><pubDate>Sun, 29 Jun 2025 00:15:48 +0000</pubDate><link>https://news.ycombinator.com/item?id=44409262</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=44409262</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=44409262</guid></item><item><title><![CDATA[New comment by new299 in "The Fifth Generation Project in Japan (1992)"]]></title><description><![CDATA[
<p>You mention SD Cards.<p>The SD Card was developed by two Japanese companies (Panasonic and Toshiba) and Sandisk.<p>VHS is another Japanese standard, adopted by multiple manufacturers.<p>Then there's the MSX standard...<p>Japanese industry is no doubt somewhat different and may have its issues. But I don't think it's as simple a picture as you paint... some external factor is often required to force large companies to cooperate. Those factors may be more common outside Japan, but I don't see that the fundamental issues are very different.</p>
]]></description><pubDate>Fri, 18 Oct 2024 09:40:25 +0000</pubDate><link>https://news.ycombinator.com/item?id=41877744</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=41877744</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=41877744</guid></item><item><title><![CDATA[New comment by new299 in "The Fifth Generation Project in Japan (1992)"]]></title><description><![CDATA[
<p>Essentially all medium to high-end ham radio brands are Japanese. Cheap Chinese radios only dominate at the low end, and often have emission issues. I doubt the Japanese manufacturers are interested in competing here...<p>Chinese radios do not dominate in Japan, I suspect almost nobody in Japan uses a non-domestic radio. Possibly the primary reason being that they generally have not passed the local emission certifications (which is annoyingly required for all ham radios).<p>I don't see the incompatible microphone thing as an issue unique to Japan. Pretty much every 1980s computer had weird propriety interfaces. I suspect it was competition that forced them to standardize. You can find similar issues more recently (Apple/Lightening port, Dell/IBM laptop chargers, docking stations etc.)<p>If you want to point to issue with ham radio in Japan, I'd go with the certification issue, which helps lock non-domestic players out of the market...</p>
]]></description><pubDate>Fri, 18 Oct 2024 09:29:25 +0000</pubDate><link>https://news.ycombinator.com/item?id=41877692</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=41877692</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=41877692</guid></item><item><title><![CDATA[New comment by new299 in "A road safety plan that will lead to cars communicating with each other"]]></title><description><![CDATA[
<p>The number of negative comments here seems odd to me.<p>If you actually want practical and safe self driving cars widely deployed it seems obvious that instrumenting roads and making them a better platform for self-driving vehicles is an important part of this process.<p>To me this work seems like a part of the process of evolving roads from a Ad-Hoc and poorly documented system involving a lot of human guess work into a more robust and reliable platform for self-driving and human driven cars.</p>
]]></description><pubDate>Tue, 20 Aug 2024 08:28:05 +0000</pubDate><link>https://news.ycombinator.com/item?id=41298013</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=41298013</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=41298013</guid></item><item><title><![CDATA[New comment by new299 in "CrowdStrike representatives issue trademark infringement notice to ClownStrike"]]></title><description><![CDATA[
<p>I wonder to what extent companies consider the reputational damage these kinds of enforcement actions cause. I recently came across this when googling for information on a small Biotech startup:<p><a href="https://udrp.adr.eu/decisions/detail?id=65fab3e46fc02956a01040a9" rel="nofollow">https://udrp.adr.eu/decisions/detail?id=65fab3e46fc02956a010...</a><p>Will probably be the first thing I remember when I hear their name.</p>
]]></description><pubDate>Thu, 01 Aug 2024 22:40:41 +0000</pubDate><link>https://news.ycombinator.com/item?id=41134394</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=41134394</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=41134394</guid></item><item><title><![CDATA[New comment by new299 in "400% increase in GPS spoofing – workgroup established"]]></title><description><![CDATA[
<p>Can a future GPS replacement or extension use signed transmissions to help address this?</p>
]]></description><pubDate>Sun, 28 Jul 2024 10:35:31 +0000</pubDate><link>https://news.ycombinator.com/item?id=41092360</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=41092360</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=41092360</guid></item><item><title><![CDATA[New comment by new299 in "How babies and young children learn to understand language"]]></title><description><![CDATA[
<p>Anyone have a link to the work he cites?</p>
]]></description><pubDate>Fri, 21 Jun 2024 06:28:18 +0000</pubDate><link>https://news.ycombinator.com/item?id=40746762</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=40746762</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=40746762</guid></item><item><title><![CDATA[New comment by new299 in "Unlocking the Duron and Athlon using the pencil (2007)"]]></title><description><![CDATA[
<p>No pencils use “lead”. It’s just called lead because the original material used looks similar to lead ore.<p>See manufacturing section here: <a href="https://en.m.wikipedia.org/wiki/Pencil" rel="nofollow">https://en.m.wikipedia.org/wiki/Pencil</a></p>
]]></description><pubDate>Sun, 02 Jun 2024 07:17:12 +0000</pubDate><link>https://news.ycombinator.com/item?id=40552082</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=40552082</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=40552082</guid></item><item><title><![CDATA[New comment by new299 in "Show HN: Open-source load balancer for llama.cpp"]]></title><description><![CDATA[
<p>llama.cpp is not CPU only…</p>
]]></description><pubDate>Sun, 02 Jun 2024 06:58:24 +0000</pubDate><link>https://news.ycombinator.com/item?id=40551980</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=40551980</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=40551980</guid></item><item><title><![CDATA[New comment by new299 in "60 kHz (2022)"]]></title><description><![CDATA[
<p>WWVB also broadcasts on 60KHz and a number of other frequencies. WWV (time signal on different frequency) was started a few years before the one you mention. Though I’m not sure it’s really worth arguing about… not sure who was the  first radio time signal.<p><a href="https://en.m.wikipedia.org/wiki/Radio_clock" rel="nofollow">https://en.m.wikipedia.org/wiki/Radio_clock</a></p>
]]></description><pubDate>Sat, 01 Jun 2024 08:17:26 +0000</pubDate><link>https://news.ycombinator.com/item?id=40543861</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=40543861</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=40543861</guid></item><item><title><![CDATA[New comment by new299 in "Apple's mysterious fisheye projection"]]></title><description><![CDATA[
<p>This was a great post, the cooling effect of litigation on posting single frames of a streamed ident (which seems to be clearly fair use). Is kind of sad to see (can’t fault the author for it really).</p>
]]></description><pubDate>Sun, 14 Apr 2024 22:33:32 +0000</pubDate><link>https://news.ycombinator.com/item?id=40035088</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=40035088</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=40035088</guid></item><item><title><![CDATA[New comment by new299 in "Gene therapy allows an 11-year-old boy to hear"]]></title><description><![CDATA[
<p>No, but creating these reagents is a lot of work.<p>Principally create new flowcells coated with an oligo lawn would be difficult. Not impossible… but a non-trivial project…</p>
]]></description><pubDate>Thu, 25 Jan 2024 05:30:01 +0000</pubDate><link>https://news.ycombinator.com/item?id=39126496</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=39126496</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=39126496</guid></item><item><title><![CDATA[New comment by new299 in "Gene therapy allows an 11-year-old boy to hear"]]></title><description><![CDATA[
<p>I’ve done this:<p><a href="https://aseq.substack.com/p/bringing-up-an-old-ebay-miseq" rel="nofollow">https://aseq.substack.com/p/bringing-up-an-old-ebay-miseq</a><p>Your issues are that you will still need to purchase reagents from the sequencing instrument vendor. They will try and push you toward a service contract.<p>Each kit will cost ~$600 (cheapest kit) an old Illumina sequencer which you can still buy reagents for will cost at least $5000.<p>Doing a whole genome this way would be expensive… I’d guess $10K to $20K perhaps? You’d need a lot of kits… or one of the high spec sequencers (NextSeq 550 etc).<p>Alternatively you could look at getting a nanopore sequencer. This will be cheap but the data quality is different (and may not be comparable/require high coverage for certain applications). I’d guess you could do a (30x) whole genome for <$10K all inc here?</p>
]]></description><pubDate>Wed, 24 Jan 2024 01:47:49 +0000</pubDate><link>https://news.ycombinator.com/item?id=39112614</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=39112614</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=39112614</guid></item><item><title><![CDATA[New comment by new299 in "High Precision Mapping from Scratch"]]></title><description><![CDATA[
<p>Fascinating, thank you!<p>I find it interesting that the boundaries are defined by a combination of physical land features and other property boundaries.<p>I guess this means that there's the error could potentially accumulate when you reference against property boundaries. Then you come up against some physical reference and have to resolve the inconsistency somehow.</p>
]]></description><pubDate>Tue, 02 Jan 2024 11:58:57 +0000</pubDate><link>https://news.ycombinator.com/item?id=38840726</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=38840726</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=38840726</guid></item><item><title><![CDATA[New comment by new299 in "$450 for a School Bag?"]]></title><description><![CDATA[
<p>I think it depends, this one didn't as IIRC we got last seasons model as it was cheaper.</p>
]]></description><pubDate>Tue, 02 Jan 2024 11:51:48 +0000</pubDate><link>https://news.ycombinator.com/item?id=38840673</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=38840673</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=38840673</guid></item><item><title><![CDATA[New comment by new299 in "$450 for a School Bag?"]]></title><description><![CDATA[
<p>They also break... ours lasted 2 years and then one of the rivets popped out.<p>Generally I believe you are allowed to use a different bag, it's just... uncommon.</p>
]]></description><pubDate>Tue, 02 Jan 2024 04:29:35 +0000</pubDate><link>https://news.ycombinator.com/item?id=38838121</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=38838121</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=38838121</guid></item><item><title><![CDATA[New comment by new299 in "Meshtastic: An open source, off-grid, decentralized, mesh network"]]></title><description><![CDATA[
<p>I bought a pile of LoRa/Meshtastic stuff and tried to research it and figure out if I could easily use something like APRS to log my location and plot it on a map.<p>Seemed much harder than the process of setting up an APRS iGate and viewing my location on aprs.fi<p>I'd like to try again sometime though, but feel like I need a good getting started guide to motivate me!</p>
]]></description><pubDate>Mon, 01 Jan 2024 05:10:30 +0000</pubDate><link>https://news.ycombinator.com/item?id=38829863</link><dc:creator>new299</dc:creator><comments>https://news.ycombinator.com/item?id=38829863</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=38829863</guid></item></channel></rss>