I'm surprised by the 2nd bit of the introduction, which initial sounds like the Canadian version of MAGA, strangely protectionist, with secondary reliance on new partners.

The comments pointing out Brock and 1812 is a reminder that US and Canada were once enemies, which I think was an unnecessary approach.

Carney doesn't put out messaging without considering every word.

It's also strange to see a head of state building an audience on youtube. Is Trump setting the playbook for politicians on social media? Perhaps not being on social media much myself, I just don't see it.

I'm Canadian, have lived in the US, and currently live in Australia.

Comments URL: https://news.ycombinator.com/item?id=47831240

Points: 1

# Comments: 1

We had both played with a bit of arduino or hobbyist stuff in the past, but dove right into EEG and neurostimulation.

Hardware is hard like software used to be hard. When we think of hardware, we're usually caught up just in the electrical chip, transistor, firmware, IO mentality.

Maybe it's just because of what we're building (https://affectablesleep.comm) but we also have to factor in mechanical design, electrical/mechanical interfaces, material science (electrode sensors), etc.

I've learned power management isn't always about, how long does my battery last, but also, how do micro-fluctuations in voltage during use impact other sensors or other operating systems.

Hardware, for us at least, has been a significantly larger footprint than we initially would have expected. It isn't just hardware, firmware, control app. For us it's been the above, plus data-quality tooling, firmware CI, in-factory provisioning and security, the list seems to go on and on.

It's a new challenge, and has been a very fun one. It does remind me a bit of the early days of the web when we'd write our own web-server, DB connection logic, etc etc.

This isn't difficult to do with someone like Trump in power. They aren't shouting "Death to America" because they don't have to. They can easily position Trump as an enemy of the people, just as American's have done to the Ayatollah in the past.

In the West, I have always felt, we were in support of the Iranian people, but not the leadership which barely represented them. Now in the US, you have a similar dichotomy.

I don't think anyone in the west is hoping for a stronger Iran, but we're also not wishing for a stronger America.

Note: I'm Canadian, but have lived in the US and have much of my family in the US

Real design would be changing how beds, showers, toilets, keys, etc etc work.

Yes there is familiarity in the truly banal, but progress in design happens when we really question how things work.

Comments URL: https://news.ycombinator.com/item?id=47811921

Points: 3

# Comments: 1

Disclosure: I am the co-founder & CEO of neurotech/sleeptech company https://affectablesleep.com

The post talks about "sleep deprivation" which most people, and most studies, view as reduced sleep time.

The latest research shows that sleep regularity is a better predictor of health (via morbidity) than sleep duration, even when sleep duration is taken into account. This is on our blog with links to research [1]

I have a few issues with the "sleep more" concept, and I often say that you wouldn't measure your diet based on how much time you spend chewing, so why do we think this is a good measure for sleep. The methodology for measuring sleep, particularly deep sleep, was defined in 1968 by the sleeping pattern 28 college aged men and 5 college aged women [2].

We are able to show that decreasing the Neural Function of Sleep, the vital processes of the brain that make sleep restorative, and specifically slow-wave activity, reduces the effectiveness of sleep without altering sleep time. We can also enhance the Neural Function of Sleep to improve health outcomes measured by memory, HRV, cortisol, immune function, and more [3] links to research.

This isn't just limited to a bunch of lab studies. As we age, the Neural Function of Sleep naturally declines, and this decline is linked to age related metabolic health, cardiac health, and of course neurological diseases and particularly dementia and Alzhiemer's. Overly focusing on "just get more sleep time" doesn't solve the problem.

To further the problem, people often blame sleep for their tiredness, when they have poor diet, don't exercise, and/or poor mental health (stress, burnout, depression, etc). You can complain all you want about the gas mileage on your car and try tuning your engine, etc, but if you've got flat tires, you're not going anywhere.

Our work in neurotech and specifically sleep is focused on some of these issues, though I think the more important thing is for people to

1) Understand what sleep schedule works for YOU and focus on consistency and regularity. 2) If you're "tired" ask yourself if you are "tired" or "lethargic" is sleep really to blame? Or could there be other things that are impacting how you feel, or impacting how well you are sleeping.

I equate what we know about sleep and the brain today as similar to what we knew about diet and exercise in the 70s. We knew it was important but we really didn't understand how it worked. What we will learn in the next decade will upend our current understanding and have a significant impact on health and longevity.

[1] https://blog.affectablesleep.com/p/the-hidden-work-of-sleep-...

[2] https://blog.affectablesleep.com/p/sleep-sciences-blind-spot...

[3] https://affectablesleep.com/how-it-works#research

Your comment about "not enough REM" sleep shows how little people truly understand about sleep. It's not REM (or even the amount of REM) that is the issue. REM is dreaming sleep and emotional processing. N3 and to a lesser extent N2, often referred to as deep sleep is the stage where the restorative activity and hormonal balance occurs.

Iran has not benefitted hugely from globalisation (unless I'm missing something), however because of globalisation and their ability to impact the global economy, they have an outsized hand to play relative to their GDP.

I think this enabled telemedicine to work in the way it does not. The patient says "I want wegovy" and the telemedicine platform says "ok, here you go".

Would telehealth pill-pushers exist without this mentality?

Due to drug advertising rules, the prescription system has been turned on its head, and the patient now goes to their doctor asking for a specific prescription.

Telemedicine took advantage of this and has effectively removed the middleman (the doctor) in many cases and you just sign-up look at a person on a camera, and get your drugs sent to you.

Though I was curious about fitting the belt into the square slot. Did it have a map of where the belt was supposed to go? Or was it able to figure out itself that it would bend to fit in that slot?

Seeing as the threat is calcium build-up in the arteries, and because cholesterol is a vital component of health, I believe that if you are in good health, and don't have a history of heart-disease, or have diabetes or other auto-immune disease which increases risk of atherosclerosis, lowering cholesterols is an in direct measure.

It's about understanding your personal risk and making decisions based on that.

The challenge is that some people, like myself, have outrageously high LDL, yet no calcium build-up in arteries via calcium score testing.

This is why ApoB is the newer more common test. Molecules containing ApoB can stick to the walls of arteries, and the theory is that the more ApoB molecules in the blood, the more likelihood of a molecule sticking and then becoming calcified.

If you have an auto-immune disease or diabetes, which increases the amount of time it takes for tears in the arteries to repair, you have a longer exposure time of fats sticking to the arterial walls which increases the likleihood of calcifying.

However, that doesn't mean that everyone with high LDL and high ApoB are at higher risk.

This is why I went for the calcium score. Don't show me the things that might lead to calcium build up later, just measure my calcium levels and let's see if I am currently at risk, and we can keep monitoring this.

Doctors are still trying to push me on to statins, but without a history of heart-disease and every other biomarker being off the charts high, I am taking that risk myself, knowing that calcium score is 0, so my suspected risk is actually very low.

Long answer, but hopefully that clarifies the understanding.

I'm not a doctor, I work in neurotech so am around health and have gone through this process myself.

Good thing I wore my tin-foil hat to dinner, but sadly, my friend didn't wear one, and now they can't get a timer for their cooking and the meal is ruined. Brilliant.

I guess I'm wondering why Apple and Google don't get the same pushback?

Main-frame (thin) -> PC (fat) -> Internet/Cloud (thin) -> Mobile (fat) -> AI (thin)

I expect this to continue until the next technology transition.

In each of these shifts, and there have been others, things are not completely fat or thin, more of an in-between state but leaning to local vs cloud.