Hacker News: ros86

New comment by ros86 in "AI-assisted PCB design for KiCad 10"

ros86 — Fri, 16 Oct 2026 14:45:15 +0000

Actually, the jlc/LCSC db does include stock and price and the basic/extended flag. This in itself makes this MCP already extremely useful.

New comment by ros86 in "Ask HN: Who is hiring? (March 2026)"

ros86 — Mon, 02 Mar 2026 20:59:01 +0000

Cradle (https://cradle.bio) | Scientific Software Engineer | Amsterdam | Onsite | Full-time

We're an AI platform for protein engineering (customers include Novo Nordisk, J&J, Grifols). We run our own wet lab in Amsterdam to generate training data for our ML models and to build the automation playbook we share openly with the field. We're hiring a software engineer to work embedded with our bioengineering team. You'd build things like: computer vision pipelines for colony picking, interfaces for lab automation workcells, integrations between lab instruments and Benchling. Python, APIs, databases, some frontend.

No PhD or biotech background needed. You'll pick up the biology. We care about solid engineering skills and curiosity about working at the intersection of software and hardware.

Apply: https://jobs.ashbyhq.com/cradlebio/7a4f7d2d-714e-4c01-84bb-9...

New comment by ros86 in "Show HN: Find startup name, with available domain name"

ros86 — Sat, 31 Aug 2024 19:38:14 +0000

Nice idea! (and very soon you have 1000s of startup ideas ;-))

New comment by ros86 in "Nebula Genomics – First to offer consumer anonymous sequencing"

ros86 — Sat, 09 Dec 2023 09:31:58 +0000

My point is not about having the cheapest solution. I just don't trust anyone else with my genomic information, even if they say it's anonymous. (I'm a biotech engineer, from Europe; maybe that explains my reservation ;-))

New comment by ros86 in "Nebula Genomics – First to offer consumer anonymous sequencing"

ros86 — Sat, 09 Dec 2023 08:50:49 +0000

At some point, I would love to setup something like this but then completely local and open-source. This could e.g. include a sequencing kit (Nanopore MinION sequencer (<$ 1,000) plus necessary consumables), protocols, and in silico workflows for basecalling, SNP calling, and interpretation.

New comment by ros86 in "Show HN: E-Ink Day Schedule"

ros86 — Mon, 25 Sep 2023 18:34:52 +0000

I can recommend checking out https://openepaperlink.de/. It's a project to repurpose e-ink electronic shelf labels (in various sizes, ranging from 1.54" to 7.4"). I have been playing around with it the last few weeks and it's a lot of fun! The community around this is very active on Discord.

New comment by ros86 in "Launch HN: Play.ht (YC W23) – Generate and clone voices from 20 seconds of audio"

ros86 — Mon, 27 Mar 2023 17:39:28 +0000

Yeah, good point - don't know. When I tried I actually did get a (personal?) email saying that it didn't match closely enough. After uploading another sample (based on a different text) it went through.

I like your idea of just training on the consent text! That wasn't the case when I tried it as you needed around 3h (optimally) of training data.

New comment by ros86 in "Launch HN: Play.ht (YC W23) – Generate and clone voices from 20 seconds of audio"

ros86 — Mon, 27 Mar 2023 17:18:33 +0000

When I tried this service previously, you had to read (out loud) something saying that you were giving consent.

New comment by ros86 in "Tell HN: Merry Christmas and Happy New Year"

ros86 — Sat, 24 Dec 2022 10:25:05 +0000

Some wonderful music from Bach, his Weihnachtsoratorium (2.5 hours): https://open.spotify.com/album/48eINR6FEINQEvDTrbig9X

New comment by ros86 in "A Microfluidic D-subminiature Connector (2013)"

ros86 — Mon, 19 Sep 2022 17:52:20 +0000

There are indeed a few practical applications. Next to Berkely lights, there is e.g. the LabChip from PerkinElmer that separates DNA and proteins. I had hoped that there would be many more examples by now. Most presentations that I see about microfluids still go in a lot of detail on how difficult it is to make. This hasn't really changed over the last decade, which signals to me we still need quite some innovation to make this mainstream.

If you want to play around with digital microfluids at home, check out the OpenDrop from gaudi.ch (http://www.gaudi.ch/OpenDrop/). I haven't played around with it yet, as I haven't found a practical use of this.

New comment by ros86 in "Bugs are evolving to eat plastic"

ros86 — Mon, 20 Dec 2021 18:00:35 +0000

In the biotech field is indeed quite common to refer to microbes as bugs. Thanks for reminding that this is ambiguous outside the field!

New comment by ros86 in "Chemistry of Cast-Iron Seasoning (2010)"

ros86 — Sun, 10 Jan 2021 21:30:14 +0000

Just a random thought (lived both in the US and in the EU): could it be that US ovens are more often gas ovens while in the EU it's mostly electric? (might be easier to get higher temperatures with gas).

Couldn't find statistics on this with a quick search...

New comment by ros86 in "Dockerfile Best Practices"

ros86 — Sun, 03 Jan 2021 14:59:26 +0000

Another useful resource is hadolint (https://github.com/hadolint/hadolint), which not only gives additional recommendations, but also a way to enforce this.

New comment by ros86 in "I should have loved biology"

ros86 — Thu, 19 Nov 2020 09:26:00 +0000

Are you interested in salary ranges in the US and/or NL?

New comment by ros86 in "I should have loved biology"

ros86 — Thu, 19 Nov 2020 08:15:18 +0000

What about some MOOCS? There are plenty that will introduce you to this area.

New comment by ros86 in "I should have loved biology"

ros86 — Thu, 19 Nov 2020 08:12:01 +0000

I think this depends a bit on the area. I work in the field of metabolic engineering (i.e. engineering microbes to make new products). When I worked at a biotech company in the Bay Area, I had a pretty decent salary, while still a bit lower than software engineers. Right now, I live in the Netherlands and my guess is that the discrepancy is a big larger here.

Royal Concertgebouw Orchestra Celebrates Beethoven Festival Online

ros86 — Mon, 02 Nov 2020 11:02:47 +0000

Article URL: https://www.concertgebouw.nl/en/beethoven-festival-online

Comments URL: https://news.ycombinator.com/item?id=24966705

Points: 2

# Comments: 0

New comment by ros86 in "From its name to its drug interactions, there’s a lot going on with grapefruit"

ros86 — Wed, 07 Oct 2020 13:14:06 +0000

I don't think so, as alcohol is not degraded via P450 enzymes..

The plunge in highly skilled work visas

ros86 — Mon, 14 Sep 2020 13:59:57 +0000

Article URL: https://www.axios.com/immigrant-work-visas-h1b-coronavirus-a9dc6aeb-60cc-46be-ae3d-aa198f8c54ba.html

Comments URL: https://news.ycombinator.com/item?id=24470210

Points: 1

# Comments: 0

New comment by ros86 in "Dishwashing detergent hack: Two ingredients (2015)"

ros86 — Thu, 13 Aug 2020 10:43:54 +0000

This isn't a scientific study of course, but still I do miss the negative reference (i.e. without any detergent). Additionally, it would be nice to quantify the 'cleanness' of a run (perhaps weighing the dishes before and after?). Hmm, perhaps we should take this study to the next level ;-).