<rss version="2.0" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Hacker News: roscoebeezie</title><link>https://news.ycombinator.com/user?id=roscoebeezie</link><description>Hacker News RSS</description><docs>https://hnrss.org/</docs><generator>hnrss v2.1.1</generator><lastBuildDate>Thu, 16 Apr 2026 06:51:56 +0000</lastBuildDate><atom:link href="https://hnrss.org/user?id=roscoebeezie" rel="self" type="application/rss+xml"></atom:link><item><title><![CDATA[New comment by roscoebeezie in "AlphaFold reveals the structure of the protein universe"]]></title><description><![CDATA[
<p>I haven’t had a chance to look through some of the new predictions, but I know there were some issues with predicting the structure for membrane bound proteins previously. PDB hardly contains any.<p>Does the new set of predictions contain a bunch of membrane bound protiens?</p>
]]></description><pubDate>Thu, 28 Jul 2022 20:19:35 +0000</pubDate><link>https://news.ycombinator.com/item?id=32269609</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=32269609</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=32269609</guid></item><item><title><![CDATA[New comment by roscoebeezie in "The Magnetar, nature’s ultimate superweapon"]]></title><description><![CDATA[
<p>I reading the article I think the ships from The Expanse were aptly named</p>
]]></description><pubDate>Sat, 18 Jun 2022 20:05:31 +0000</pubDate><link>https://news.ycombinator.com/item?id=31793328</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=31793328</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=31793328</guid></item><item><title><![CDATA[New comment by roscoebeezie in "Migrating extraterrestrial civilizations and interstellar colonization"]]></title><description><![CDATA[
<p>Sounds almost like the Protomolecule from The Expanse series.</p>
]]></description><pubDate>Fri, 27 May 2022 16:58:03 +0000</pubDate><link>https://news.ycombinator.com/item?id=31531880</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=31531880</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=31531880</guid></item><item><title><![CDATA[New comment by roscoebeezie in "Earn-IT threatens encryption and therefore user freedom"]]></title><description><![CDATA[
<p>It’s entirely possible I don’t understand how technology works, but I don’t understand how some sort of government encryption backdoor of various protocols would work.<p>Software, devices, protocols etc are not just used in a single country. They are used worldwide. If a backdoor needs to be supported for a several dozen governments, each with various levels of security practices, there’s no way it stays secret for long. It’s only a matter of time before a country or state like Georgia gets it’s old poorly configured IT infrastructure hacked and the attackers now have access to some backdoor keys. How do governments revoke old keys and create new ones across all applicable devices? It’d be pretty hard to do that without going to companies and saying “fix” or “get me that” with some type of warrant or court order. That is kinda like what we have now which is mostly limited user information located in the cloud somewhere.<p>I think the larger issue is that there is a coordinated push to get complete government access to everything. This is happening at a time where dystopian surveillance is not only quickly becoming possible, but also profitable. The government has the right to pretty much everything legally, but the potential for misuse in situations where the government gets access everything is really high. The ability for citizens to combat that misuse is reduced the more government gets.<p>This is my understanding of things. Let me know how I’m wrong.</p>
]]></description><pubDate>Fri, 11 Mar 2022 04:41:09 +0000</pubDate><link>https://news.ycombinator.com/item?id=30636274</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=30636274</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=30636274</guid></item><item><title><![CDATA[New comment by roscoebeezie in "NASA’s new shortcut to fusion power"]]></title><description><![CDATA[
<p>Maybe excess energy could be used to recycle limited and precious elements from landfills via Santa Claus machine-like disassembly with very hot plasma. Horribly energy inefficient but may be useful in some situations.</p>
]]></description><pubDate>Tue, 01 Mar 2022 03:29:37 +0000</pubDate><link>https://news.ycombinator.com/item?id=30509055</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=30509055</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=30509055</guid></item><item><title><![CDATA[New comment by roscoebeezie in "New cancer therapy holds potential to switch off major cancer types"]]></title><description><![CDATA[
<p>Disclaimer: I’m not a scientist, but I want to be.<p>For things like cancer cells which from a cell surface perspective, can look a lot like healthy cells, I don’t know how one only modifies DNA/RNA expression in only cancer cells. It would have to be all cells with maybe some cellular diagnosis logic in the DNA/RNA itself. Even then cancer evolves. It would have to done multiple times with something like cell descendents information.</p>
]]></description><pubDate>Wed, 01 Dec 2021 03:24:58 +0000</pubDate><link>https://news.ycombinator.com/item?id=29400307</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=29400307</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=29400307</guid></item><item><title><![CDATA[New comment by roscoebeezie in "IT professionals should work in a mainframe environment at some point (2015)"]]></title><description><![CDATA[
<p>I think the author is just another oh so popular mainframe evangelist as he's stated. He could have easily made the same case for any properly managed distributed system.<p>Where I disagree with him is that I don't think right out of college professionals should be working in a mainframe environment. As a person who has spent the past 3.5 years (right out of college) working in mainframe capacity planning and performance, I think mainframe technology can be pretty niche and I very nervously wonder if my very specific mainframe systems engineering experience will translate anywhere else. I feel as though getting a new tech professional started in their career would be better in an environment that is popular and they are familiar with, and then working from there.</p>
]]></description><pubDate>Fri, 28 Jun 2019 04:16:23 +0000</pubDate><link>https://news.ycombinator.com/item?id=20301423</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=20301423</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=20301423</guid></item><item><title><![CDATA[New comment by roscoebeezie in "Ask HN: Who wants to be hired? (April 2019)"]]></title><description><![CDATA[
<p>Location: Atlanta, GA<p>Remote: No<p>Willing to relocate: Yes<p>Technologies: Python(Pandas,Numpy, etc)/SAS/R/Mainframe/VBA<p>Resume: Email if needed<p>Email: roscoe1245@gmail.com<p>I'm a Systems Engineer Currently doing work in Mainframe Performance and capacity planning. I've got a background in analysis/math, but I'm looking for more of a Data Engineer or software development role. I'd be open to other possibilities as well.</p>
]]></description><pubDate>Thu, 04 Apr 2019 02:54:21 +0000</pubDate><link>https://news.ycombinator.com/item?id=19568957</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=19568957</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=19568957</guid></item><item><title><![CDATA[New comment by roscoebeezie in "Ask HN: Can we write a programming language for biology?"]]></title><description><![CDATA[
<p>I'm not OP, but what about the realm outside of rational protien design? DNA base paring rules are pretty well understood and we should be able to build useful tools using them. Is there any work out there using only for computation?</p>
]]></description><pubDate>Mon, 07 Jan 2019 18:05:28 +0000</pubDate><link>https://news.ycombinator.com/item?id=18847961</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=18847961</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=18847961</guid></item><item><title><![CDATA[New comment by roscoebeezie in "Banner ads on CNN.com contain keyloggers"]]></title><description><![CDATA[
<p>I’ve noticed CNN has had a crap ton of redirect ads recently...</p>
]]></description><pubDate>Tue, 17 Jul 2018 16:45:26 +0000</pubDate><link>https://news.ycombinator.com/item?id=17551036</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=17551036</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=17551036</guid></item><item><title><![CDATA[New comment by roscoebeezie in "Ask HN: Are there any reasonable alternatives to MacBook Pro for developer?"]]></title><description><![CDATA[
<p>Realtek.</p>
]]></description><pubDate>Tue, 10 Apr 2018 02:02:28 +0000</pubDate><link>https://news.ycombinator.com/item?id=16798475</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=16798475</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=16798475</guid></item><item><title><![CDATA[New comment by roscoebeezie in "Ask HN: Are there any reasonable alternatives to MacBook Pro for developer?"]]></title><description><![CDATA[
<p>X230 user here (non-IPS). The touchpad isnt just crap, it’s unusable. I’ve also had issues with non-intel wireless card.</p>
]]></description><pubDate>Sun, 08 Apr 2018 14:34:32 +0000</pubDate><link>https://news.ycombinator.com/item?id=16786241</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=16786241</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=16786241</guid></item><item><title><![CDATA[New comment by roscoebeezie in "Ask HN: Who wants to be hired? (April 2018)"]]></title><description><![CDATA[
<p>Location: Atlanta, Georgia<p>Remote: Yes<p>Willing to relocate: Yes<p>Technologies: Python, SQL, SAS, R, a bit of JavaScript and Java,Deep Learning.<p>Resume: via email 
Email: roscoe1245@gmail.com<p>I’m a Systems Engineer with a few years doing Capacity Planning and Performance for mostly legacy mainframe systems. I have done a bit of work doing data analytics as well. I’m looking for more of a developer type role. I have an interest in AI, Robotics, and Biology.</p>
]]></description><pubDate>Thu, 05 Apr 2018 13:28:58 +0000</pubDate><link>https://news.ycombinator.com/item?id=16764688</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=16764688</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=16764688</guid></item><item><title><![CDATA[New comment by roscoebeezie in "Ask HN: Resources to learn real analysis?"]]></title><description><![CDATA[
<p>One thing that helped me was to draw pictures both before and during proofs.</p>
]]></description><pubDate>Sat, 24 Mar 2018 16:36:12 +0000</pubDate><link>https://news.ycombinator.com/item?id=16667448</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=16667448</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=16667448</guid></item><item><title><![CDATA[New comment by roscoebeezie in "Airlines inching closer to dynamic pricing"]]></title><description><![CDATA[
<p>Yeah as a person who works heavily in the airline ticket pricing world, that’s not how it works.</p>
]]></description><pubDate>Sun, 25 Feb 2018 20:31:39 +0000</pubDate><link>https://news.ycombinator.com/item?id=16461012</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=16461012</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=16461012</guid></item><item><title><![CDATA[New comment by roscoebeezie in "Scaling Kubernetes to 2,500 Nodes"]]></title><description><![CDATA[
<p>As a person who doesn’t understand containers, where do I go to learn the basics?</p>
]]></description><pubDate>Thu, 18 Jan 2018 21:07:37 +0000</pubDate><link>https://news.ycombinator.com/item?id=16181462</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=16181462</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=16181462</guid></item><item><title><![CDATA[New comment by roscoebeezie in "Using thought to control machines"]]></title><description><![CDATA[
<p>I once had the exact same idea as these guys.</p>
]]></description><pubDate>Mon, 08 Jan 2018 10:26:04 +0000</pubDate><link>https://news.ycombinator.com/item?id=16095828</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=16095828</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=16095828</guid></item><item><title><![CDATA[New comment by roscoebeezie in "Priceline now worth $100B"]]></title><description><![CDATA[
<p>The three: Amedeus, Sabre, Travelport(Galileo, Apollo, Worldspan).<p>Disclaimer: I work for one of these.</p>
]]></description><pubDate>Thu, 27 Jul 2017 01:22:37 +0000</pubDate><link>https://news.ycombinator.com/item?id=14861910</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=14861910</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=14861910</guid></item><item><title><![CDATA[New comment by roscoebeezie in "Netlify CMS – An open-source CMS for Git workflows"]]></title><description><![CDATA[
<p>When CMS is not Conversational​ Monitor System...</p>
]]></description><pubDate>Fri, 17 Mar 2017 20:08:41 +0000</pubDate><link>https://news.ycombinator.com/item?id=13897519</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=13897519</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=13897519</guid></item><item><title><![CDATA[New comment by roscoebeezie in "United Airlines Domestic Flights Grounded for 2 Hours by Computer Outage"]]></title><description><![CDATA[
<p>Yeah a lot of this stuff is on old school mainframes written in assembly. I work in the airline/travel industry and I've seen 28 year old code still running in production.</p>
]]></description><pubDate>Mon, 23 Jan 2017 02:39:54 +0000</pubDate><link>https://news.ycombinator.com/item?id=13459287</link><dc:creator>roscoebeezie</dc:creator><comments>https://news.ycombinator.com/item?id=13459287</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=13459287</guid></item></channel></rss>