Hacker News: rpmisms

New comment by rpmisms in "We Think the SpaceX IPO Is Overvalued"

rpmisms — Tue, 09 Jun 2026 22:20:58 +0000

Doesn't really matter. Elon just has a good track record of delivering value for investors, and will move mountains to make it happen.

New comment by rpmisms in "We Think the SpaceX IPO Is Overvalued"

rpmisms — Tue, 09 Jun 2026 02:44:11 +0000

I'm generally going to avoid betting against Elon.

New comment by rpmisms in "Project Hail Mary – Stellar Navigation Chart"

rpmisms — Fri, 22 May 2026 03:16:06 +0000

Fantasizing about saving the universe is a good thing, actually.

New comment by rpmisms in "Project Hail Mary – Stellar Navigation Chart"

rpmisms — Thu, 21 May 2026 22:04:43 +0000

Star Trek (TNG onwards) gets this right.

New comment by rpmisms in "Project Hail Mary – Stellar Navigation Chart"

rpmisms — Thu, 21 May 2026 17:51:26 +0000

White people doing anything good is actually bad. Duh.

/s, but I think I'm accurately describing the viewpoint you're responding to.

New comment by rpmisms in "Starship's Twelfth Flight Test"

rpmisms — Wed, 20 May 2026 23:38:10 +0000

Historically, that has been true about rockets.

New comment by rpmisms in "Starship's Twelfth Flight Test"

rpmisms — Wed, 20 May 2026 22:58:20 +0000

Have you met hardware guys? This is not how they operate, in my experience.

New comment by rpmisms in "Kimi K2.6 just beat Claude, GPT-5.5, and Gemini in a coding challenge"

rpmisms — Sun, 03 May 2026 04:47:23 +0000

Sounds incredibly simple to me. One-shot.

New comment by rpmisms in "Supreme Court to hear arguments in landmark Roundup weedkiller case"

rpmisms — Tue, 28 Apr 2026 02:31:34 +0000

You can absolutely avoid glyphosate in your diet. This is obviously some sort of emotional issue for you.

New comment by rpmisms in "Supreme Court to hear arguments in landmark Roundup weedkiller case"

rpmisms — Tue, 28 Apr 2026 01:12:48 +0000

Call it (pun intended) a smell test. I have cited a study that shows biomarkers of gut inflammation strongly correlated with glyphosate exposure. Perhaps you should have read it.

I have raised a flag. Lowering your exposure to a novel chemical agent that directly impacts a massive and poorly-understood symbiotic system within the body isn't a bad response. Glyphosate exposure certainly isn't beneficial, so I'll treat it like Pascal's wager: avoiding this has more upside than downside.

New comment by rpmisms in "Supreme Court to hear arguments in landmark Roundup weedkiller case"

rpmisms — Tue, 28 Apr 2026 01:06:10 +0000

Can you attack the methodology or data instead of the author?

New comment by rpmisms in "Supreme Court to hear arguments in landmark Roundup weedkiller case"

rpmisms — Tue, 28 Apr 2026 01:04:39 +0000

Maybe you should see if you adjust to the bran flakes, cut them out if you don't improve, and see if there's a difference? All sorts of things can disrupt gut biomes, and I think ancestral diets are an interesting area of study. Gut inflammation is absolutely rampant.

New comment by rpmisms in "Supreme Court to hear arguments in landmark Roundup weedkiller case"

rpmisms — Tue, 28 Apr 2026 00:54:56 +0000

I'm not trying to make a complete argument, I'm trying to raise a flag. This issue is not well-studied and has very large corporate sponsors who would like to keep selling Roundup-Ready™ crops. One particular measurable function is inhibition of the shikamate pathway in many different bacteria (the majority of the volume of your gut flora is affected).

Here's a decent paper that shows an adverse effect: https://pmc.ncbi.nlm.nih.gov/articles/PMC10330715/

I understand that this is the realm of crunchy weirdos, but thinking holistically doesn't mean you need to lobotomize yourself.

Here's another paper examining some brain effects of chronic gut inflammation, which could be reasonably inferred as a potential consequence of long-term glyphosate exposure: https://pmc.ncbi.nlm.nih.gov/articles/PMC10661239/

New comment by rpmisms in "Supreme Court to hear arguments in landmark Roundup weedkiller case"

rpmisms — Mon, 27 Apr 2026 21:44:58 +0000

Well, I didn't intend that as a conversation-ender, but it is true. This particular substance inhibits a particular function of certain gut flora that seems important. I think it's safe to call that significant.

New comment by rpmisms in "Supreme Court to hear arguments in landmark Roundup weedkiller case"

rpmisms — Mon, 27 Apr 2026 20:49:33 +0000

Here's a decent one: 13% of the UK reports gluten intolerance symptoms, and only 7% of Germany does. The UK allows pre-harvest glyphosate desiccation, Germany doesn't. I would be happy to bet that the trend continues past my quick Google search.

New comment by rpmisms in "Supreme Court to hear arguments in landmark Roundup weedkiller case"

rpmisms — Mon, 27 Apr 2026 20:46:02 +0000

We know that it's really important to neurological function, which is enough reason to be careful.

New comment by rpmisms in "Supreme Court to hear arguments in landmark Roundup weedkiller case"

rpmisms — Mon, 27 Apr 2026 17:23:01 +0000

The mechanism of action of glyphosate inhibits several important amino acid production processes in the gut. I'm simplifying here, but not having glyphosate in the food supply would be a good thing for the gut, and the science agrees on this.

Glyphosate for field prep also doesn't really come through in food, it's much worse with the pre-harvest desiccation.

New comment by rpmisms in "Supreme Court to hear arguments in landmark Roundup weedkiller case"

rpmisms — Mon, 27 Apr 2026 17:17:04 +0000

The best-reasoned criticism of glyphosate is that it disrupts the gut biome (this is a fact). I suspect that many "gluten allergies" are actually gut biome problems from glyphosate-desiccated wheat.

New comment by rpmisms in "Incident with multple GitHub services"

rpmisms — Fri, 24 Apr 2026 13:19:38 +0000

That really does put it in perspective. Wow.

New comment by rpmisms in "The dangers of California's legislation to censor 3D printing"

rpmisms — Fri, 17 Apr 2026 17:10:39 +0000

Yawn. We're a remarkably peaceful country. We should kill more of our criminals, though.