<rss version="2.0" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Hacker News: samuell</title><link>https://news.ycombinator.com/user?id=samuell</link><description>Hacker News RSS</description><docs>https://hnrss.org/</docs><generator>hnrss v2.1.1</generator><lastBuildDate>Fri, 26 Jun 2026 04:50:24 +0000</lastBuildDate><atom:link href="https://hnrss.org/user?id=samuell" rel="self" type="application/rss+xml"></atom:link><item><title><![CDATA[New comment by samuell in "Qualcomm to Acquire Modular"]]></title><description><![CDATA[
<p>No, this was pure speculation based on what seems like a popular view on where Mojo ended up, where the initial Python-focus don't seem to help it that much anymore.</p>
]]></description><pubDate>Wed, 24 Jun 2026 16:08:39 +0000</pubDate><link>https://news.ycombinator.com/item?id=48661989</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48661989</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48661989</guid></item><item><title><![CDATA[New comment by samuell in "Qualcomm to Acquire Modular"]]></title><description><![CDATA[
<p>As a meta comment, I'm surprised such a news is not reaching the frontpage already.</p>
]]></description><pubDate>Wed, 24 Jun 2026 15:57:30 +0000</pubDate><link>https://news.ycombinator.com/item?id=48661833</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48661833</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48661833</guid></item><item><title><![CDATA[New comment by samuell in "Qualcomm to Acquire Modular"]]></title><description><![CDATA[
<p>Maybe Chris was a little unhappy about where Mojo ended up, and sees this as an opportunity to start anew on a properly designed language from scratch :D</p>
]]></description><pubDate>Wed, 24 Jun 2026 15:41:14 +0000</pubDate><link>https://news.ycombinator.com/item?id=48661596</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48661596</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48661596</guid></item><item><title><![CDATA[New comment by samuell in "Qualcomm to Acquire Modular"]]></title><description><![CDATA[
<p>I'm actually mostly worried about the future of Mojo at this time.<p>Though hopefully it will be fully released open source still, but I feel there are question marks around whether it will be a priority to continue to develop by Qualcomm, or if they are mainly interested in the AI compute stack?<p>Time will tell I guess, but a lot feels to be up in the air.</p>
]]></description><pubDate>Wed, 24 Jun 2026 14:30:35 +0000</pubDate><link>https://news.ycombinator.com/item?id=48660548</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48660548</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48660548</guid></item><item><title><![CDATA[New comment by samuell in "Clojure Hosted on Go"]]></title><description><![CDATA[
<p>Found this previous thread about Lisette:
<a href="https://news.ycombinator.com/item?id=47646843">https://news.ycombinator.com/item?id=47646843</a></p>
]]></description><pubDate>Thu, 18 Jun 2026 10:10:51 +0000</pubDate><link>https://news.ycombinator.com/item?id=48583225</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48583225</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48583225</guid></item><item><title><![CDATA[New comment by samuell in "DaVinci Resolve 21"]]></title><description><![CDATA[
<p>I'll second looking at KdenLive.<p>You might want to stay away from very recent major versions for stability, but it is a very capable editor that is also much more robust and performant than openshot.<p>I haven't compared with Blender VSE though.</p>
]]></description><pubDate>Thu, 04 Jun 2026 10:49:59 +0000</pubDate><link>https://news.ycombinator.com/item?id=48396801</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48396801</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48396801</guid></item><item><title><![CDATA[New comment by samuell in "DaVinci Resolve 21"]]></title><description><![CDATA[
<p>Wanted to expand on the animation part, so will check this up for sure, thank you.</p>
]]></description><pubDate>Wed, 03 Jun 2026 16:45:05 +0000</pubDate><link>https://news.ycombinator.com/item?id=48386387</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48386387</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48386387</guid></item><item><title><![CDATA[New comment by samuell in "DaVinci Resolve 21"]]></title><description><![CDATA[
<p>Great to hear.</p>
]]></description><pubDate>Wed, 03 Jun 2026 16:44:18 +0000</pubDate><link>https://news.ycombinator.com/item?id=48386377</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48386377</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48386377</guid></item><item><title><![CDATA[New comment by samuell in "DaVinci Resolve 21"]]></title><description><![CDATA[
<p>Stability sounds interesting. While KdenLive has worked OKish for me, certain versions have broken my projects, and there are some long-standing bugs, like subtitles disappearing if I do a specific operation in the wrong moment. While the latter is fixed by a simple Ctrl+Z it is giving me second thoughts about using this for really large projects.</p>
]]></description><pubDate>Wed, 03 Jun 2026 16:43:51 +0000</pubDate><link>https://news.ycombinator.com/item?id=48386370</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48386370</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48386370</guid></item><item><title><![CDATA[New comment by samuell in "DaVinci Resolve 21"]]></title><description><![CDATA[
<p>For people using Resolve, would you recommend someone already quite well-versed in KDenLive to switch, for some non-profit work on cutting together educational content with some animations, some talks etc?<p>Will it allow me to drastically improve my workflow (save time for some tedious tasks), increase quality of the outputs etc?</p>
]]></description><pubDate>Wed, 03 Jun 2026 15:58:02 +0000</pubDate><link>https://news.ycombinator.com/item?id=48385806</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48385806</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48385806</guid></item><item><title><![CDATA[New comment by samuell in "Zig: Build System Reworked"]]></title><description><![CDATA[
<p>My main issue with this is I expect Mojo to become the go to tinkering language for me.</p>
]]></description><pubDate>Sat, 30 May 2026 12:33:15 +0000</pubDate><link>https://news.ycombinator.com/item?id=48335502</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48335502</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48335502</guid></item><item><title><![CDATA[New comment by samuell in "Ask HN: When and why did you start believing in God?"]]></title><description><![CDATA[
<p>I grew up in a christian home, so got my initial belief from there.<p>Had a kind of pivot moment when I moved out from home though, where I immediately realized my parents will not be there forever, and the inner me needs to reach for my ultimate parent. This got me into a much closer relation with the Lord. I had (and have) many somewhat spectacular answers to prayer, and basically learned to have a really trustful relationship with him.<p>I know many people's faith is challenged when going to the university and learning about biology as I did (studying biotech and bioinformatics).<p>I had came into contact with some great apologetics material, especially around evolution etc, in Swedish, which I found super interesting.<p>Still, I must say my faith was even more reinforced when we started to study macro-molecular machines, and I realized that biology is a whole world of extremely advanced nano-machines, working in an extremely intricate network of interlocking interdependencies.<p>I've been involved in quite a bit of debates regarding evolutionism and creationism over the years, and one thing I have noticed is that scientific creationism is much closer to modern evolutionary theory than most people realize. Recent secular paradigms such as "The third way of evolution" [1] pretty much perfectly recapitulates what many creationists have said for years; Biology is shock-full of pre-programmed ability to adapt, according to pre-existing modules and adjustable parameters, in an extremely dynamic software system, with tons of generative algorithms for how animals and plants are built up through embryogenesis, which allows for powerful adjustments of a lot of parameters with often surprisingly little change in the genomic "source code".<p>For people interested in an introduction to what secular science has to say here, I often recommend "The Plausability of Life", by Gerhart and Kirschner [2]. Other great titles are "Evolution: A View from the 21st century" by James Shapiro [3], and a few more (the third way website lists a lot of great books).<p>In my view, the Genesis story in the Bible matches these findings perfectly, disagreeing mainly in the expected age of things. But these biological mechanisms actually mean that "evolution" can happen extremely fast, without even actual genomic changes just by turning on and off or regulating features, via mechanisms like Epigenetics.<p>Eventually I've became involved in trying to figure out the more detailed view of how the Biblical narrative could explain the bleeding edge of biology, which led me to co-organize a seminar in Sweden in 2024 with European researchers (mostly), which resulted in both a video series and a book, which is available from this web store among others (not affiliated).<p>This work, especially the chapters on 1) Mendelian genetics 2) Epigenetics and 3) Transposable elements (think Endogenous Retroviruses, Jumping Genes etc), together in my mind creates an extremely interesting explanatory framework for how life was pre-programmed to be extremely efficient - and fast - mind you - at adapting to varying environments.<p>Whether you want to call that "evolution" or "pre-programmed adaptive creation" is in my mind very much a question of definitions, and TBF, the term evolution hasn't had a very strict definition for as long as I remember.<p>Anyways, today I'm more fascinated than ever the more I learn about the extremely complex and ingenuous solutions out there in nature to vastly different problem areas like chemistry, metabolism, mechanics, information processing and general cognition. It fills me with awe and respect for the creator that must be there behind all this.<p>[1] <a href="https://www.thethirdwayofevolution.com/" rel="nofollow">https://www.thethirdwayofevolution.com/</a><p>[2] <a href="https://yalebooks.yale.edu/book/9780300119770/the-plausibility-of-life/" rel="nofollow">https://yalebooks.yale.edu/book/9780300119770/the-plausibili...</a><p>[3] <a href="https://www.goodreads.com/book/show/11004717-evolution" rel="nofollow">https://www.goodreads.com/book/show/11004717-evolution</a><p>[4] <a href="https://www.youtube.com/playlist?list=PLNkVOx7YbWiDABv5nB3IhPNi1g14SPHO_" rel="nofollow">https://www.youtube.com/playlist?list=PLNkVOx7YbWiDABv5nB3Ih...</a><p>[5] <a href="https://store.answersingenesis.co.uk/product/a-creation-science-perspective-on-the-origin-of-diversity-in-biological-life/BJODQIO4LZ3OW2X5U3E4NJZI" rel="nofollow">https://store.answersingenesis.co.uk/product/a-creation-scie...</a></p>
]]></description><pubDate>Fri, 29 May 2026 17:53:15 +0000</pubDate><link>https://news.ycombinator.com/item?id=48326774</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48326774</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48326774</guid></item><item><title><![CDATA[New comment by samuell in "Local-First and Portable CI"]]></title><description><![CDATA[
<p>Optimizing for local-first checking is 100% the way to go, and should be used much more widely I think.<p>I have done a similar thing using simple makefiles though, collecting more complex chains of tasks into a "meta rule" in Make and just calling that from whatever CI config we're using.</p>
]]></description><pubDate>Thu, 28 May 2026 16:46:45 +0000</pubDate><link>https://news.ycombinator.com/item?id=48311596</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48311596</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48311596</guid></item><item><title><![CDATA[New comment by samuell in "Rosalind: A genomics toolkit in Rust running whole-genome pipelines on a laptop"]]></title><description><![CDATA[
<p>You might try sequencing your DNA at home :)<p><a href="https://iwantosequencemygenomeathome.com/" rel="nofollow">https://iwantosequencemygenomeathome.com/</a><p>(Well, the guy offers to do it for you too, delivering the data on an USB stick).</p>
]]></description><pubDate>Wed, 27 May 2026 12:59:23 +0000</pubDate><link>https://news.ycombinator.com/item?id=48293603</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48293603</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48293603</guid></item><item><title><![CDATA[New comment by samuell in "Rosalind: A genomics toolkit in Rust running whole-genome pipelines on a laptop"]]></title><description><![CDATA[
<p>> So it seems "Rosalind" is at least very appropriate as a name for a genomics tool such as this.<p>Indeed. The only argument against it might be that Rosalind is already a pretty well-known website for doing bioinformatics exercises and have them automatically graded:<p><a href="https://rosalind.info" rel="nofollow">https://rosalind.info</a></p>
]]></description><pubDate>Wed, 27 May 2026 12:50:40 +0000</pubDate><link>https://news.ycombinator.com/item?id=48293480</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48293480</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48293480</guid></item><item><title><![CDATA[New comment by samuell in "Rosalind: A genomics toolkit in Rust running whole-genome pipelines on a laptop"]]></title><description><![CDATA[
<p>I shared this since it seems to address a somewhat similar niche that I have had hopes to one day develop, based on FlowBase [1]; A library of streaming processing components based on basic operations, that can be easily stitched together into larger pipelines in a compiled language that can run on smaller hardware too.<p>FlowBase or I didn't have much of ideas about how to keep data structures compact, as the linked library does, and I was mostly aiming to make it really easy to build streaming pipelines.<p>I haven't yet got my head around how the composability story is in rosalind though, so would be interested in any pointers or examples on how this would be done using it.<p>[1] <a href="https://github.com/flowbase/flowbase" rel="nofollow">https://github.com/flowbase/flowbase</a></p>
]]></description><pubDate>Wed, 27 May 2026 09:18:12 +0000</pubDate><link>https://news.ycombinator.com/item?id=48291672</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48291672</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48291672</guid></item><item><title><![CDATA[New comment by samuell in "Rosalind: A genomics toolkit in Rust running whole-genome pipelines on a laptop"]]></title><description><![CDATA[
<p>Yeah, there is actually a pretty big shift towards Rust in the comp bio / bioinformatics community.<p>Nature even wrote a feature article about it a couple years ago:<p>Why scientists are turning to Rust<p><a href="https://www.nature.com/articles/d41586-020-03382-2" rel="nofollow">https://www.nature.com/articles/d41586-020-03382-2</a><p>They mention the Rust-Bio [1] project by well known Snakemake author Johannes Köster & co, and there are some other widely used libraries like needletail [2] and noodles [3].<p>A cool smaller tool developed by performance wiz Ragnar Groot Koerkamp which was just published is Sassy [4] [5]. He has also been involved in developing some high performance SIMD based stuff (minimizers) [6].<p>[1] <a href="https://github.com/rust-bio/rust-bio" rel="nofollow">https://github.com/rust-bio/rust-bio</a><p>[2] <a href="https://github.com/onecodex/needletail" rel="nofollow">https://github.com/onecodex/needletail</a><p>[3] <a href="https://github.com/zaeleus/noodles" rel="nofollow">https://github.com/zaeleus/noodles</a><p>[4] <a href="https://github.com/RagnarGrootKoerkamp/sassy" rel="nofollow">https://github.com/RagnarGrootKoerkamp/sassy</a><p>[5] <a href="https://academic.oup.com/bioinformatics/article/42/5/btag244/8691840" rel="nofollow">https://academic.oup.com/bioinformatics/article/42/5/btag244...</a><p>[6] <a href="https://github.com/rust-seq/simd-minimizers" rel="nofollow">https://github.com/rust-seq/simd-minimizers</a></p>
]]></description><pubDate>Wed, 27 May 2026 09:13:09 +0000</pubDate><link>https://news.ycombinator.com/item?id=48291632</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48291632</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48291632</guid></item><item><title><![CDATA[Rosalind: A genomics toolkit in Rust running whole-genome pipelines on a laptop]]></title><description><![CDATA[
<p>Article URL: <a href="https://github.com/logannye/rosalind">https://github.com/logannye/rosalind</a></p>
<p>Comments URL: <a href="https://news.ycombinator.com/item?id=48222600">https://news.ycombinator.com/item?id=48222600</a></p>
<p>Points: 185</p>
<p># Comments: 57</p>
]]></description><pubDate>Thu, 21 May 2026 13:55:13 +0000</pubDate><link>https://github.com/logannye/rosalind</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48222600</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48222600</guid></item><item><title><![CDATA[New comment by samuell in "Show HN: Files.md – Open-source alternative to Obsidian"]]></title><description><![CDATA[
<p>I want something like this, but completely terminal based</p>
]]></description><pubDate>Mon, 18 May 2026 15:15:07 +0000</pubDate><link>https://news.ycombinator.com/item?id=48181008</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48181008</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48181008</guid></item><item><title><![CDATA[New comment by samuell in "Mojo 1.0 Beta"]]></title><description><![CDATA[
<p>I'm really quite divided about Rust vs Mojo for bioinformatics in the future.<p>The syntax i Mojo really seems to shine a lot ... though I still wonder if the train has already left now that so much bioinfo work is already done in Rust.</p>
]]></description><pubDate>Sat, 16 May 2026 10:07:38 +0000</pubDate><link>https://news.ycombinator.com/item?id=48158713</link><dc:creator>samuell</dc:creator><comments>https://news.ycombinator.com/item?id=48158713</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=48158713</guid></item></channel></rss>