Hacker News: sytse

New comment by sytse in "Things to know when you get cancer"

sytse — Thu, 15 Oct 2026 21:17:08 +0000

“Check out all the resources and materials at the Sijbrandij Foundation. Sid (GitLab cofounder) took matters into his own hands when standard of care ran out. Schedule a call with these guys. They are great and have good materials and questions to ask your doctors.”

Thanks for your kind words about FCCT from the Sijbrandij Foundation. We help people look beyond the standard of care for cancer. Calling with them is a free service.

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sun, 29 Mar 2026 04:41:08 +0000

cancer@sytse.com is a good address to reach out to. Thanks for reaching out. I look forward to discussing. You can find some of my ideas in slides https://share.icloud.com/photos/020eRAUd5TqDwlypQCT-qhK7w

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sun, 29 Mar 2026 04:38:08 +0000

Glad to hear that!

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sun, 29 Mar 2026 01:33:24 +0000

There are lots of waivers but the law prevents you from signing away liability for treatment.

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sun, 29 Mar 2026 01:30:58 +0000

Not that easy but started Echo to make it easier https://www.echoimmune.com/

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sun, 29 Mar 2026 01:28:00 +0000

Thanks, I replied to your email.

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sun, 29 Mar 2026 01:26:01 +0000

Dank je!

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sat, 28 Mar 2026 23:53:26 +0000

It wasn’t easy to learn it while dealing with the side effects of chemo. But AI helped a lot, also see the OpenAI forum talked linked on the page. Love BillionToOne, also see https://osteosarc.com/timeline/ MRD Northstar for my results with it.

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sat, 28 Mar 2026 23:27:48 +0000

Yes, I’ve met many people already. Feel free to reach out if you have questions cancer@sytse.com

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sat, 28 Mar 2026 22:21:03 +0000

Thanks for the warning, I hope that it wasn't a personal experience for you.

Thanks for the compliment about the elaborate design. I think that when you make something for one or a few patients it is easier to be more elaborate, even with the same knowledge and equipment.

Maybe the TCR and BCR-seq was most helpful for mRNA design and effectiveness monitoring, but hopefully someone else on my team will answer that better.

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sat, 28 Mar 2026 22:17:59 +0000

Of course it depends on what they need but please email cancer@sytse.com with a screenshot of this message and we can discuss.

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sat, 28 Mar 2026 22:16:10 +0000

Really appreciate it. I agree the capability is here today. I'm trying to get it to more people so that the learning effects and economies of scale can bring the costs down.

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sat, 28 Mar 2026 22:13:43 +0000

I'm not knowledgable able fibrosis except that my tumor expresses a lot of FAP and it is a workable target for radio and immune drugs.

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sat, 28 Mar 2026 22:00:42 +0000

Thank you! I've been cancer free for 10 months now. If you're curious please see https://osteosarc.com/timeline/ > MRD > Personalis.

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sat, 28 Mar 2026 21:58:04 +0000

Certainly hospitals are in the business of minimizing liability while patients would prefer maximum survivability. Those are very different goals.

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sat, 28 Mar 2026 21:56:48 +0000

Thanks for you kinds words, glad to hear you recovered from Peyronies.

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sat, 28 Mar 2026 21:55:34 +0000

Yes, it felt like the universe provided in this case. I invest in my batch mate. We end up becoming best friends, our wifes become best friends. Biotech VCs are afraid click chemistry isn't hot enough. I lead multiple rounds and become the biggest investor and it becomes my biggest investment. The year I get cancer click-chemistry wins a Nobel prize. And I become a patient. Unbelievable.

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sat, 28 Mar 2026 21:52:56 +0000

All of these companies (including the Even One Ventures and Open Core Ventures ones) have CEOs who run them day to day. I try to help with positioning and setting ambitious goals. Y Combinator really opened my eyes to how helpful setting clear and hard to reach goals is.

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sat, 28 Mar 2026 21:50:56 +0000

Doing well. We've not seen the cancer for 10 months (not for lack of trying) and I'm enjoying an international trip for pleasure!

New comment by sytse in "Founder of GitLab battles cancer by founding companies"

sytse — Sat, 28 Mar 2026 21:49:21 +0000

I have a stoic mindset, I try to not care about things that are outside my sphere of influence. While the cancer was unfortunate it was out of my control. Having my YCW15 batchmate step up for me during my initial set of treatments to get me Shasqi opened my eyes that I could help create and take new medicines. It was within my sphere of influence. When I reached the end of standard of care I stepped down from the CEO role of GitLab and pushed to do this for me. While it was hard it was easier than I expected and I created companies to help other patients in the same way (maximum diagnostics and single patient IND pathway).