Hacker News: throw20261022

New comment by throw20261022 in "Ask HN: If the models are so good, why doesn't OpenAI just start 100 companies?"

throw20261022 — Thu, 22 Oct 2026 21:57:07 +0000

Selling tokens in conjunction with a phone number or credit card yields signals for surveillance for intelligence agencies that can be tied to individuals. This keeps the firms relatively out of trouble with the federal government. This makes them too big to fail. Being subject to such surveillance is in fact is a strong reason for conscious individuals to seek to move away from them in the long term once the quality of competing AIs reaches a shared plateau.

They're doing the other thing too via numerous startup acquisitions.

New comment by throw20261022 in "AI analysis of CT scans finds 42.9% of patients have coronary inflammation"

throw20261022 — Thu, 22 Oct 2026 19:16:45 +0000

As for hs-CRP, I already explained the basis in my comment. It depends on whether they mean correlation in its strict literal sense or only after binary classification.

As for Lp-PLA2, they crucially seem to have ignored it altogether.

New comment by throw20261022 in "AI analysis of CT scans finds 42.9% of patients have coronary inflammation"

throw20261022 — Thu, 22 Oct 2026 19:02:23 +0000

> Crucially, no routine blood biomarker, lipid metric, or clinical risk score could identify these individuals with inflamed coronary arteries.

I call bs on this. There are two common blood tests that are meant for it:

1) hs-CRP (High-sensitivity CRP)

2) Lp-PLA2: Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as platelet activating factor Acetylhydrolase, is an inflammatory enzyme that circulates bound mainly to low density lipoproteins and has been found to be localized and enriched in atherosclerotic plaques. In multiple clinical trials, Lp-PLA2 activity has been shown to be an independent predictor of coronary heart disease and stroke in the general population. Measurement of Lp-PLA2 may be used along with traditional cardiovascular risk factor measures for identifying individuals at higher risk of cardiovascular disease events.

I have routinely had both of these blood tests among others, although I paid myself to get them.

As for hs-CRP, it will likely show an elevation. If you use a binary classifier with a higher threshold of what's safe, e.g. 3.0 instead of 1.0, you will miss it! I am guessing this is why they missed it.

New comment by throw20261022 in "OpenAI CLI"

throw20261022 — Thu, 22 Oct 2026 06:18:19 +0000

Be careful getting too deep in OpenAI tooling because they end up deprecating almost everything in under two years, sometimes without even a formal notice.

Everything they make these days looks to be strongly vibecoded without a decent review or functional testing. This leads to basic avoidable bugs that annoy vast numbers of users.

Not only this, but when you point out an issue to them on GitHub, they have a history of blocking the reporting user instead of tackling the technical issue.