<rss version="2.0" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Hacker News: ticking</title><link>https://news.ycombinator.com/user?id=ticking</link><description>Hacker News RSS</description><docs>https://hnrss.org/</docs><generator>hnrss v2.1.1</generator><lastBuildDate>Fri, 17 Apr 2026 14:32:52 +0000</lastBuildDate><atom:link href="https://hnrss.org/user?id=ticking" rel="self" type="application/rss+xml"></atom:link><item><title><![CDATA[New comment by ticking in "Optimizing CRISPR: Sub-second searches on a 3 billion base genome"]]></title><description><![CDATA[
<p>The method they accidentally found is not as bad as you make it to be.<p><a href="https://en.wikipedia.org/wiki/Rabin–Karp_algorithm" rel="nofollow">https://en.wikipedia.org/wiki/Rabin–Karp_algorithm</a><p>Rabin karp with rolling hashes is actually (not exactly but almost) what tools like rsync, or bittorent use to find chunks and differences in files. So it scales really well.<p>The algorithms you cite come from a time when computers looked rather different in their architectures.<p>Linearly scanning the entire genome from ram for example, could be significantly better than performing multiple index lookups from disk.<p>Many problems of bioinformatics (the text processing) aren't that hard or special anymore, a genome is tiny compared to the amount of data we have lying around elsewhere.</p>
]]></description><pubDate>Fri, 24 Jul 2015 02:28:20 +0000</pubDate><link>https://news.ycombinator.com/item?id=9939811</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9939811</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9939811</guid></item><item><title><![CDATA[New comment by ticking in "Optimizing CRISPR: Sub-second searches on a 3 billion base genome"]]></title><description><![CDATA[
<p>Have you thought about using the hammond distance, instead of the array?<p>It should give you the same answer in 3 CPU instructions on registers instead of 2 array lookups and arithmetic in ram. XOR, hammond weight/bitcount and and equality check.</p>
]]></description><pubDate>Fri, 24 Jul 2015 02:21:07 +0000</pubDate><link>https://news.ycombinator.com/item?id=9939793</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9939793</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9939793</guid></item><item><title><![CDATA[New comment by ticking in "Neurosurgeon launches £900,000 crowd-funding appeal"]]></title><description><![CDATA[
<p>This is the mentioned indiegogo campaign
<a href="https://www.indiegogo.com/projects/revolutionary-treatment-for-deadliest-child-cancer#/story" rel="nofollow">https://www.indiegogo.com/projects/revolutionary-treatment-f...</a><p>sadly it looks like they are still quite far away from their goal.</p>
]]></description><pubDate>Fri, 17 Jul 2015 12:54:47 +0000</pubDate><link>https://news.ycombinator.com/item?id=9902462</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9902462</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9902462</guid></item><item><title><![CDATA[New comment by ticking in "Adverts for robot housekeepers are terrifying a lot of people"]]></title><description><![CDATA[
<p>A lot of people = some idiots on twitter, that have no clue about the current state of technology</p>
]]></description><pubDate>Mon, 11 May 2015 14:39:40 +0000</pubDate><link>https://news.ycombinator.com/item?id=9525066</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9525066</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9525066</guid></item><item><title><![CDATA[New comment by ticking in "Chris Granger on the LightTable architecture"]]></title><description><![CDATA[
<p><a href="http://www.selflanguage.org" rel="nofollow">http://www.selflanguage.org</a><p>You should watch the videos on the introduction page and play a bit with the system, it's interesting to see how much interactivity and liveliness was already achieved in the 80s/90s,</p>
]]></description><pubDate>Sat, 18 Apr 2015 13:54:53 +0000</pubDate><link>https://news.ycombinator.com/item?id=9399456</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9399456</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9399456</guid></item><item><title><![CDATA[New comment by ticking in "The death of optimizing compilers [pdf]"]]></title><description><![CDATA[
<p>The fie is huge because it seems that animations were converted to multiple PDF pages.<p>So page count is not a useful metric for presentation progression and information amount.</p>
]]></description><pubDate>Sat, 18 Apr 2015 11:41:39 +0000</pubDate><link>https://news.ycombinator.com/item?id=9399099</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9399099</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9399099</guid></item><item><title><![CDATA[New comment by ticking in "Chris Granger on the LightTable architecture"]]></title><description><![CDATA[
<p>> It never said it was the "the uber clojure IDE", not even used any words to this effect.<p>In the beginning it was clearly marketed as a clojure ide,
and if you look at the comments on HN at the time it's clear that it was perceived as such.<p><a href="http://www.chris-granger.com/2012/04/12/light-table---a-new-ide-concept/" rel="nofollow">http://www.chris-granger.com/2012/04/12/light-table---a-new-...</a><p><a href="https://news.ycombinator.com/item?id=3836978" rel="nofollow">https://news.ycombinator.com/item?id=3836978</a><p>>"Catering too much to other languages"? What does that even mean? Did anybody signed to the parent that it would only be for his favorite language (the "uber clojure IDE" he dreamt?)? It was due to huge community demand that LT promised to support Javascript and Python too.<p>This is what broke it's back though. By trying to go with all languages at once they failed to focus on getting one right first. They should have added new ones later on.<p>>Nobody stopped the parent or anyone else from using something existing "that actually works" or creating something even better.<p>I've heard it many times over the years in the clojure world, "I'd start on an editor, but it looks like LT is going to be exactly what I want so I'll just wait." Only after its failure was apparent things like Gorilla-Repl popped up.<p>> including having concretely inspired the Swift playground features (as the Swift designer admitted).<p>I'd like a source for that. LT is directly inspired by the work of Bred Victor who _worked for apple_ and Swift has at least one of the Factor devs, which is a highly dynamic language with a live coding environment.<p>> As if it was all a scheme to make $300K off of kickstarter.
He made a lot more than that on Kickstarter, and has some Venture capital as well iirc.<p>Chris has a history of half finished unmaintained projects, so especially with his past I'd be suspicious.<p>Eve is the same, it promises to make programming mainstream but storing your UI in a Datalog DB is a huge mess. DL is great, but the stuff he does with it is just horrid.</p>
]]></description><pubDate>Fri, 17 Apr 2015 00:42:43 +0000</pubDate><link>https://news.ycombinator.com/item?id=9391670</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9391670</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9391670</guid></item><item><title><![CDATA[New comment by ticking in "Chris Granger on the LightTable architecture"]]></title><description><![CDATA[
<p>They didn't contain much of the live programming story?<p><a href="https://www.youtube.com/watch?v=Ox5P7QyL774" rel="nofollow">https://www.youtube.com/watch?v=Ox5P7QyL774</a><p><a href="https://www.youtube.com/watch?v=3ka4KY7TMTU" rel="nofollow">https://www.youtube.com/watch?v=3ka4KY7TMTU</a></p>
]]></description><pubDate>Fri, 17 Apr 2015 00:24:03 +0000</pubDate><link>https://news.ycombinator.com/item?id=9391608</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9391608</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9391608</guid></item><item><title><![CDATA[New comment by ticking in "Chris Granger on the LightTable architecture"]]></title><description><![CDATA[
<p>Yes, I also dug into its codebase.
Have you actually used Self for example?</p>
]]></description><pubDate>Fri, 17 Apr 2015 00:19:34 +0000</pubDate><link>https://news.ycombinator.com/item?id=9391590</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9391590</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9391590</guid></item><item><title><![CDATA[New comment by ticking in "Chris Granger on the LightTable architecture"]]></title><description><![CDATA[
<p>LT didn't bring any new inventions, emacs, self, morphic, CL, they've all done some aspect of it 30 years earlier.<p>LT has shown however that you can make a load of money of kickstarter without delivering a product, but people will still throw money at you for building the next big unfinished thing (see their new pet project with a broken architecture called EVE).</p>
]]></description><pubDate>Wed, 15 Apr 2015 04:28:54 +0000</pubDate><link>https://news.ycombinator.com/item?id=9378883</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9378883</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9378883</guid></item><item><title><![CDATA[New comment by ticking in "Chris Granger on the LightTable architecture"]]></title><description><![CDATA[
<p>It's good that LT is finally acknowledged to have failed as "the uber clojure IDE". It's architecture is horrible, and its catering too much to other languages.<p>Once it's dead the space it frees up can be filled again by something that actually works.</p>
]]></description><pubDate>Tue, 14 Apr 2015 23:17:11 +0000</pubDate><link>https://news.ycombinator.com/item?id=9377945</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9377945</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9377945</guid></item><item><title><![CDATA[New comment by ticking in "Less is more: language features"]]></title><description><![CDATA[
<p>If you install nightly builds on a production system you deserve to get bitten.</p>
]]></description><pubDate>Tue, 14 Apr 2015 09:24:37 +0000</pubDate><link>https://news.ycombinator.com/item?id=9373015</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9373015</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9373015</guid></item><item><title><![CDATA[New comment by ticking in "Show HN: Kaiwa, a Modern Open-Source XMPP Web Client"]]></title><description><![CDATA[
<p>>modern ... XMPP ...<p>lolnope</p>
]]></description><pubDate>Wed, 08 Apr 2015 16:02:21 +0000</pubDate><link>https://news.ycombinator.com/item?id=9341701</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9341701</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9341701</guid></item><item><title><![CDATA[New comment by ticking in "How I Start: Clojure"]]></title><description><![CDATA[
<p>You said it better than me.</p>
]]></description><pubDate>Tue, 07 Apr 2015 21:30:40 +0000</pubDate><link>https://news.ycombinator.com/item?id=9337303</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9337303</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9337303</guid></item><item><title><![CDATA[New comment by ticking in "How I Start: Clojure"]]></title><description><![CDATA[
<p>Depends on the lisp.</p>
]]></description><pubDate>Tue, 07 Apr 2015 21:29:17 +0000</pubDate><link>https://news.ycombinator.com/item?id=9337297</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9337297</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9337297</guid></item><item><title><![CDATA[New comment by ticking in "How I Start: Clojure"]]></title><description><![CDATA[
<p>I really don't see the advantage of trying to sell clojure and emacs as a package, it just alienates a lot of potential newcomers. Sadly almost every Clojure tutorial I've seen so far does this.<p>Most tutorials for other programming languages simply go with a text editor of your choice + a console repl.</p>
]]></description><pubDate>Tue, 07 Apr 2015 18:27:07 +0000</pubDate><link>https://news.ycombinator.com/item?id=9336008</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9336008</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9336008</guid></item><item><title><![CDATA[New comment by ticking in "How I Start: Clojure"]]></title><description><![CDATA[
<p>Why though?
Cursive has a working debugger while Emacs doesn't.
Emacs has a lot of stuff outside the realm of Clojure, like irc mail and orgmode, but Cursive really is the more advanced Clojure environment.
Even @dnolen seems to have switched to it.</p>
]]></description><pubDate>Tue, 07 Apr 2015 18:24:07 +0000</pubDate><link>https://news.ycombinator.com/item?id=9335983</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9335983</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9335983</guid></item><item><title><![CDATA[New comment by ticking in "Scientists Seek Ban on Method of Editing the Human Genome"]]></title><description><![CDATA[
<p>Bullshit. I'm in my early 20s and have MS. That is not a feature.</p>
]]></description><pubDate>Fri, 20 Mar 2015 12:54:04 +0000</pubDate><link>https://news.ycombinator.com/item?id=9237337</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9237337</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9237337</guid></item><item><title><![CDATA[New comment by ticking in "Artoo: Ruby on Robots"]]></title><description><![CDATA[
<p>I agree 100% with you. Rigidity is something you don't want, but this is something entirely different.<p>ROS serialisation format is basically a C++ struct that gets send over the wire. You specify your .msg definition, tell the (horrible) build system that you want to use it, and the build system will compile it to deserialisation code in your language. During deserialisation of C/C++ this code will just try to recast the message from a void* buffer to a valid .msg struct.<p>So O(1) message parsing, nice in theory, but also what causes the rigidity that makes it harder for dynamic languages that would easily be capable to deal with a self-encoding message format.<p>But because you end up with this unsafe recasting "parser", you  _really_ want to feed it what it expects, and this is why during tcpros handshake between two clients they will exchange hashes of the msg format that they speak.<p>Note that this is fundamentally different from JSON where you are adding fields. JSON _will still work_, as long as the new message is a superset of the old one.<p>But with ros msgs a command might end up putting your nice robotic arm into the table/human because you changed the LED from a green one to a multicoloured that has a field `color[3]` instead of `color`. The field will use up more space, and the field that came after it, say `arm-height`, will now have the color value in it.<p>But we got the hash of messages to protect us from this right?<p>NO! Because the build system does a half assed normalisation step on each .msg format in which it removes comments, reformats and reorders fields and tries to find the canonical _textual_ representation of messages.
Sadly somebody forgot to keep the arity (variable/tuple/list) in there. So it gets thrown out and is not part of the hash.<p>Source: I build a ros-msg deserializer from scratch for clojure that can import message definitions at runtime, compiling them into ad-hock deserialisers.</p>
]]></description><pubDate>Fri, 20 Mar 2015 12:38:47 +0000</pubDate><link>https://news.ycombinator.com/item?id=9237266</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9237266</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9237266</guid></item><item><title><![CDATA[New comment by ticking in "Why care about functional programming? Part 1: Immutability"]]></title><description><![CDATA[
<p>Just do<p><pre><code>  public foo(Bar bar) {
        bar = baz(bar);
        //Lots (10+ lines) of code
        return finishProcess(bar);  //Note, this should have been updatedBar.
  }
</code></pre>
nothing prevents you from reusing the variable name.
The point about immutability is that the objects themselves don't change.</p>
]]></description><pubDate>Fri, 20 Mar 2015 03:43:40 +0000</pubDate><link>https://news.ycombinator.com/item?id=9236133</link><dc:creator>ticking</dc:creator><comments>https://news.ycombinator.com/item?id=9236133</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=9236133</guid></item></channel></rss>