<rss version="2.0" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Hacker News: topham</title><link>https://news.ycombinator.com/user?id=topham</link><description>Hacker News RSS</description><docs>https://hnrss.org/</docs><generator>hnrss v2.1.1</generator><lastBuildDate>Wed, 22 Apr 2026 16:37:08 +0000</lastBuildDate><atom:link href="https://hnrss.org/user?id=topham" rel="self" type="application/rss+xml"></atom:link><item><title><![CDATA[New comment by topham in "Acetaminophen vs. ibuprofen"]]></title><description><![CDATA[
<p>Not really. Both address different sources of pain, and do so using different processes.<p>Ibuprofen is a Nonsteroidal Anti-inflammatory Drug (NSAID) that reduces pain and inflammation, while acetaminophen does not. (Acetaminophen is believed to act mainly in the brain rather than at the site of injury).<p>Ibuprofen- Fundamentally, if the pain is caused by inflammation, reducing the immune systems response to it can reduce pain, but if the pain is more acute it won't make a dent.<p>With acetaminophen, taking more isn't a solution in most cases, you need another method to reduce the pain further if it doesn't achieve its goal.<p>(That's why it's combined with things like codeine, which affects the brain in a different way for an additive effect)</p>
]]></description><pubDate>Wed, 22 Apr 2026 06:16:28 +0000</pubDate><link>https://news.ycombinator.com/item?id=47859738</link><dc:creator>topham</dc:creator><comments>https://news.ycombinator.com/item?id=47859738</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47859738</guid></item><item><title><![CDATA[New comment by topham in "Acetaminophen vs. ibuprofen"]]></title><description><![CDATA[
<p>There are some that are very hard to find as a single ingredient. Recently I was purchasing a medication for back pain, I had a choice as to which other ingredient I wanted, but I didn't have the choice of none. I picked the combined ingredient I don't like to take, because I wouldn't be adding it on top.<p>I did toss on the other option, stand alone, at one point so I could get some sleep.<p>It left the medication I was more comfortable taking as an add-on option if things got bad enough. (This particular medication has much lower risk of overdose, so if I got stupid and took it again there would be no significant additional risk.)<p>It's ironic, but taking the combined medication with a known higher risk of its own was better than taking the lower risk medication.<p>One was controlled, higher risk, taken at specific times, while the other was taken in addition, on demand, as required.</p>
]]></description><pubDate>Wed, 22 Apr 2026 06:09:13 +0000</pubDate><link>https://news.ycombinator.com/item?id=47859690</link><dc:creator>topham</dc:creator><comments>https://news.ycombinator.com/item?id=47859690</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47859690</guid></item><item><title><![CDATA[New comment by topham in "Acetaminophen vs. ibuprofen"]]></title><description><![CDATA[
<p>The right tool for the right job. When it comes to medication, in the right dosage.<p>I'm aware of acetaminophen's down sides, and yet recently I was taking it combined with 2 other medications at the time.<p>Why? Because all three medications are recommended for dealing with the issue I had. (Alone and in combination)<p>The moment it wasn't helping further? Done.<p>There is this broken idea, particularly apparent in North America, but in western society that more is better for many things. It's not.<p>More pain killers don't do anything if they max out the relief they can give you, overloading their mechanism doesn't reduce anything, but taxing your liver or your kidneys.<p>All medications are potentially toxic, your body wants to dispose of them. In appropriate dosages they will benefit you, but more isn't inherently better.<p>Even water can kill you in sufficient quantity.<p>We do the same with diet; where someone declares one ingredient in a meal healthier than another; it isn't. A single ingredient isn't better or worse for you in a meal. Your diet however can be good or bad; over time that matters.</p>
]]></description><pubDate>Wed, 22 Apr 2026 06:00:49 +0000</pubDate><link>https://news.ycombinator.com/item?id=47859639</link><dc:creator>topham</dc:creator><comments>https://news.ycombinator.com/item?id=47859639</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47859639</guid></item><item><title><![CDATA[New comment by topham in "NIST scientists create 'any wavelength' lasers"]]></title><description><![CDATA[
<p>This is true, and illusionary at the same time.<p>While our precise perception of red may not match, the interplay between colors is such that people perceived them to go together, or clash, etc, in a somewhat consistent fashion.<p>This means that, over the general population the perception of color is very similar from person to person. Ignoring genetic defects.</p>
]]></description><pubDate>Sun, 19 Apr 2026 04:24:30 +0000</pubDate><link>https://news.ycombinator.com/item?id=47821778</link><dc:creator>topham</dc:creator><comments>https://news.ycombinator.com/item?id=47821778</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47821778</guid></item><item><title><![CDATA[New comment by topham in "Is ChatGPT's web front end being intentionally degraded?"]]></title><description><![CDATA[
<p>Their app is trash too for performance. If they generate some code and markdown the widgets to work with them perform like absolutely garbage.</p>
]]></description><pubDate>Sun, 19 Apr 2026 01:31:11 +0000</pubDate><link>https://news.ycombinator.com/item?id=47821078</link><dc:creator>topham</dc:creator><comments>https://news.ycombinator.com/item?id=47821078</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47821078</guid></item></channel></rss>