Hacker News: vibrio

New comment by vibrio in "Blood cells from 80-year-old donor become stem cells with molecular age under 20"

vibrio — Tue, 13 Oct 2026 01:57:14 +0000

Remind me of the chance some same AI kills us all before 10 years?

New comment by vibrio in "Show HN: A simple to-do app for iPhone, Mac, and your agent"

vibrio — Sat, 10 Oct 2026 12:24:11 +0000

I do, and I’m pretty militant about distracted driving. Long drives are captive time to think. Not rarely is there a “oh snap, that needs to get done on Tuesday not Friday” moment. Adjusting that hands free in natural language is useful.

New comment by vibrio in "Clinical trial of a prion disease drug candidate begins enrolling participants"

vibrio — Sat, 10 Oct 2026 11:55:59 +0000

I like this take. With its reduction to “survival of the fittest” slogan, it is easy to forget that Evolution can be “subjective”, imprecise in the problems it is solving.

New comment by vibrio in "AI hallucination nearly triggers US Military operation"

vibrio — Sat, 19 Sep 2026 11:14:16 +0000

New comment by vibrio in "Pentagon weighs pulling nearly a third of U.S. forces from Europe"

vibrio — Fri, 18 Sep 2026 10:27:28 +0000

..or a crappy casino. (further precedents)

New comment by vibrio in "Pentagon weighs pulling nearly a third of U.S. forces from Europe"

vibrio — Fri, 18 Sep 2026 10:23:09 +0000

Circling the wagons and tending our own garden is a nice ideal, but is no panacea just because we build some factories in Cleveland, celebrate the end of Globalism , claim ‘US energy independence’ (that’s gotten quiet lately.) reassessing our footprint? Yes great idea. Large poorly thought-through snap actions because headlines are needed? No thanks.

New comment by vibrio in "No cities on the Moon – there isn't enough water, scientists say"

vibrio — Thu, 17 Sep 2026 10:25:30 +0000

What you say is all true. Put down that book and take a trip to a Corpus Christi Texas city council meeting (eg), and help get all that silly confusion sorted out.

New comment by vibrio in "Hackers Got Inside a Flock Camera"

vibrio — Thu, 17 Sep 2026 10:07:58 +0000

Doh! (Switches on vpn)

New comment by vibrio in "Hackers Got Inside a Flock Camera"

vibrio — Thu, 17 Sep 2026 09:59:31 +0000

I wish this was just an anecdote rather than an axiom.

New comment by vibrio in "No cities on the Moon – there isn't enough water, scientists say"

vibrio — Mon, 14 Sep 2026 09:11:42 +0000

Moon? I’m starting to wonder if there’s enough water for cities on earth.

New comment by vibrio in "Spaceships (Reverse Asteroid)"

vibrio — Mon, 14 Sep 2026 02:57:57 +0000

Batttlezone was the tank game.

New comment by vibrio in "AlphaGenome Atlas: a high-resolution map of human DNA"

vibrio — Wed, 09 Sep 2026 08:51:39 +0000

What are their data privacy and security policies? That is an important consideration.

New comment by vibrio in "At-home test for infected ticks could improve Lyme Disease diagnosis"

vibrio — Sun, 16 Aug 2026 11:21:43 +0000

…and a trusted doctor isn’t necessarily a replacement for the CDC.

New comment by vibrio in "Show HN: Programmable timer web app (for gym workouts or stretching sessions)"

vibrio — Thu, 13 Aug 2026 01:48:01 +0000

Nice work! Love it.

New comment by vibrio in "Schools are adding pepper-spraying drones to help combat active shooters"

vibrio — Wed, 29 Jul 2026 01:03:12 +0000

Wtf world do we live in that this sentence exists.

New comment by vibrio in "Clinical failure rates over the decades: yikes"

vibrio — Mon, 27 Jul 2026 10:03:33 +0000

To add a somewhat cynical view, a significant part of the original motivation for the ranibizumab (Lucentis) development was due to pricing arbitrage across diseases. bevicizumab was priced based on uses in cancer indications with a “large” volume (many mls) used for systemic infusion. The same product injected into the eye, in say a 1:1000 volume, could be efficacious for AMD, but pricing per volume would be trivial amount at the bevi cost per volume. So they tweaked the active ingredient to a new product (exact same mechanism ) and raised the price per volume to a market standard cost per treatment. There may be some pk-type benefits to the derivative , but the pricing context is an industry case study.

New comment by vibrio in "Couple pay >$800k for a gene-editing therapy for their daughter. She died."

vibrio — Fri, 24 Jul 2026 07:55:01 +0000

I agree with you that AAV is clearly a useful tool but at times the low levels of self discipline and scientific rigor that the field has applied to dosing is disappointing at best and scary at times. This includes use of other vector types such as by bluebirdbio and even the Jesse Gelsinger tragedy. “If a little is good then more is better” is a crazy and lazy way to apply and optimize these technologies.

New comment by vibrio in "How to sequence your own DNA at home"

vibrio — Tue, 07 Jul 2026 01:38:02 +0000

I suspect there is a deep sequencing service that is non CLIA and cheap. True. they may not be trustworthy with the data. That said, there are steps here where the data is put into Claude. Do we trust that ?

New comment by vibrio in "What a 98-Year Old Children's Book Teaches Us About AI"

vibrio — Sat, 30 May 2026 10:57:57 +0000

Maybe also an interesting case study in the inconsistent application of copyright law.

New comment by vibrio in "Danish Pension Blacklists SpaceX over 'Catastrophic Governance'"

vibrio — Sat, 30 May 2026 10:43:56 +0000

I think their point is not the ESG component, but firms with traditionally irrational valuations (à la GameStop) for which index inclusion exceptions have been made to facilitate short term liquidity for IPO participants. Seems as though one should be able to hold the broad market less that component.