<rss version="2.0" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:atom="http://www.w3.org/2005/Atom"><channel><title>Hacker News: yshrestha</title><link>https://news.ycombinator.com/user?id=yshrestha</link><description>Hacker News RSS</description><docs>https://hnrss.org/</docs><generator>hnrss v2.1.1</generator><lastBuildDate>Sat, 05 Sep 2026 07:11:06 +0000</lastBuildDate><atom:link href="https://hnrss.org/user?id=yshrestha" rel="self" type="application/rss+xml"></atom:link><item><title><![CDATA[New comment by yshrestha in "Ask HN: Who is hiring? (March 2026)"]]></title><description><![CDATA[
<p>Innolitics | Medical Device Engineers + Physician-Scientist (MD/PhD) | REMOTE (US) | Full-Time<p>Innolitics builds AI/ML software for medical devices — the kind that detects ear infections, tracks metastatic cancer, and plans radiation therapy. 60+ FDA clearances. We need engineers who want their work to matter.
We're a remote-only firm (since 2012) that does engineering, regulatory, and cybersecurity under one roof. Our team includes MDs, PhDs, and software engineers. Clients range from Series A startups to large device companies.
We're hiring for three roles:<p>1. Physician-Scientist (MD/PhD) — Biostatistics & AI Software Development
MD + PhD in biostatistics, bioinformatics, epidemiology, or a related quantitative field. You'll design biostatistical plans for AI validation studies (MRMC, standalone, prospective), build production-grade statistical software and data pipelines, write FDA-facing statistical sections, and analyze large clinical imaging datasets. Fluent in Python and/or R. This is not a pure research role — you'll ship code that gets FDA-cleared and deployed in clinics.<p>2. Senior Web/Mobile Medical Device Engineer
5+ years SWE experience. 3+ years each in web and mobile. Fluent in TypeScript and Python. You'll build medical device software and produce FDA-facing technical documentation. Cross-functional role bridging engineering and regulatory teams.<p>3. Medical Device Software Engineer
3+ years SWE experience. Fluent in Python, C++, or TypeScript. Heavier emphasis on software development initially; you'll grow into regulatory documentation work over time.
All roles involve writing production code for medical devices, authoring documentation for FDA submissions, and working directly with clients. No prior medical device experience required — we'll teach you.
Why engineers stay here:<p>Agentic AI tools (Claude Code, etc.) are part of our workflow. We treat them as a impact multiplier, not a threat.
~1 hour of meetings/week for ICs. Flexible hours.
2 hours every Wednesday dedicated to learning ("10x Time").
Healthcare-only revenue. No debt. Never had a layoff.
We pay $300 for take-home exercises because your time has value.<p>Stack: Python, TypeScript, C++, R, Django, React, TensorFlow, PyTorch, scikit-learn, Qt, Terraform.<p>Apply: <a href="https://innolitics.com/careers/" rel="nofollow">https://innolitics.com/careers/</a><p>How we work (we publish our handbook): <a href="https://innolitics.com/about/handbook/" rel="nofollow">https://innolitics.com/about/handbook/</a></p>
]]></description><pubDate>Tue, 03 Mar 2026 13:55:38 +0000</pubDate><link>https://news.ycombinator.com/item?id=47232351</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=47232351</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=47232351</guid></item><item><title><![CDATA[New comment by yshrestha in "Frustrated with slow AI adoption? Your culture is the problem not your engineers"]]></title><description><![CDATA[
<p>I think the term "vibe coding" has no universally accepted definition but if you mean "coding without any prior coding experience" then the answer is no. Any leadership that know even the slightest about software know that AI tooling is on a spectrum. Vibe coding is at one end and tools like Claude Code and Cursor are on the other.</p>
]]></description><pubDate>Sun, 18 Jan 2026 00:47:36 +0000</pubDate><link>https://news.ycombinator.com/item?id=46663718</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=46663718</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=46663718</guid></item><item><title><![CDATA[New comment by yshrestha in "Frustrated with slow AI adoption? Your culture is the problem not your engineers"]]></title><description><![CDATA[
<p>Author here.<p>Finally, you can ask your leadership to give you time to pay back technical debt. And AI adoption is the reason why.<p>I have been seeing a pattern where leadership buys Copilot/Cursor licenses and expects immediate 10x gains, but the engineering team struggles to adopt them.<p>The thesis of this article is that AI acts as a throughput multiplier. If your codebase is clean (SOLID, DRY, explicit interfaces), AI accelerates you. If your codebase is spaghetti or relies on "tribal knowledge" (implicit context), AI just generates bugs faster than you can fix them.<p>I argue that "clean code" is no longer an aesthetic preference but a hard requirement for AI enablement, because AI agents effectively have no long-term memory of your project's history.<p>Curious if others are seeing this friction between "AI expectations" and "Legacy Code reality"?</p>
]]></description><pubDate>Sat, 17 Jan 2026 20:10:35 +0000</pubDate><link>https://news.ycombinator.com/item?id=46661566</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=46661566</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=46661566</guid></item><item><title><![CDATA[Frustrated with slow AI adoption? Your culture is the problem not your engineers]]></title><description><![CDATA[
<p>Article URL: <a href="https://innolitics.com/articles/ai-native-engineering-transformation/">https://innolitics.com/articles/ai-native-engineering-transformation/</a></p>
<p>Comments URL: <a href="https://news.ycombinator.com/item?id=46661557">https://news.ycombinator.com/item?id=46661557</a></p>
<p>Points: 4</p>
<p># Comments: 4</p>
]]></description><pubDate>Sat, 17 Jan 2026 20:09:02 +0000</pubDate><link>https://innolitics.com/articles/ai-native-engineering-transformation/</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=46661557</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=46661557</guid></item><item><title><![CDATA[You're falling behind. It's time to catch up]]></title><description><![CDATA[
<p>Article URL: <a href="https://www.youtube.com/watch?v=Z9UxjmNF7b0">https://www.youtube.com/watch?v=Z9UxjmNF7b0</a></p>
<p>Comments URL: <a href="https://news.ycombinator.com/item?id=46589202">https://news.ycombinator.com/item?id=46589202</a></p>
<p>Points: 1</p>
<p># Comments: 1</p>
]]></description><pubDate>Mon, 12 Jan 2026 14:44:54 +0000</pubDate><link>https://www.youtube.com/watch?v=Z9UxjmNF7b0</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=46589202</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=46589202</guid></item><item><title><![CDATA[Roadmap: Healthcare AI]]></title><description><![CDATA[
<p>Article URL: <a href="https://www.bvp.com/atlas/roadmap-healthcare-ai">https://www.bvp.com/atlas/roadmap-healthcare-ai</a></p>
<p>Comments URL: <a href="https://news.ycombinator.com/item?id=41680226">https://news.ycombinator.com/item?id=41680226</a></p>
<p>Points: 1</p>
<p># Comments: 0</p>
]]></description><pubDate>Sat, 28 Sep 2024 13:51:36 +0000</pubDate><link>https://www.bvp.com/atlas/roadmap-healthcare-ai</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=41680226</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=41680226</guid></item><item><title><![CDATA[Dual Energy CT Scanners at Airports [video]]]></title><description><![CDATA[
<p>Article URL: <a href="https://www.youtube.com/watch?v=nyG8XAmtYeQ">https://www.youtube.com/watch?v=nyG8XAmtYeQ</a></p>
<p>Comments URL: <a href="https://news.ycombinator.com/item?id=40138684">https://news.ycombinator.com/item?id=40138684</a></p>
<p>Points: 2</p>
<p># Comments: 0</p>
]]></description><pubDate>Tue, 23 Apr 2024 23:41:14 +0000</pubDate><link>https://www.youtube.com/watch?v=nyG8XAmtYeQ</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=40138684</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=40138684</guid></item><item><title><![CDATA[Canon Bubble Jet Technology [video]]]></title><description><![CDATA[
<p>Article URL: <a href="https://www.youtube.com/watch?v=ywz1RrXNQqw">https://www.youtube.com/watch?v=ywz1RrXNQqw</a></p>
<p>Comments URL: <a href="https://news.ycombinator.com/item?id=40100863">https://news.ycombinator.com/item?id=40100863</a></p>
<p>Points: 1</p>
<p># Comments: 0</p>
]]></description><pubDate>Sat, 20 Apr 2024 20:44:24 +0000</pubDate><link>https://www.youtube.com/watch?v=ywz1RrXNQqw</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=40100863</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=40100863</guid></item><item><title><![CDATA[New comment by yshrestha in "Devin: AI Software Engineer"]]></title><description><![CDATA[
<p>As a human, I can tell you that I suck at predicting exponential growth.</p>
]]></description><pubDate>Wed, 13 Mar 2024 02:08:29 +0000</pubDate><link>https://news.ycombinator.com/item?id=39687356</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=39687356</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=39687356</guid></item><item><title><![CDATA[Task Manager with the Original Author]]></title><description><![CDATA[
<p>Article URL: <a href="https://www.youtube.com/watch?v=Ve95Nh690l0">https://www.youtube.com/watch?v=Ve95Nh690l0</a></p>
<p>Comments URL: <a href="https://news.ycombinator.com/item?id=36347739">https://news.ycombinator.com/item?id=36347739</a></p>
<p>Points: 2</p>
<p># Comments: 0</p>
]]></description><pubDate>Thu, 15 Jun 2023 22:40:48 +0000</pubDate><link>https://www.youtube.com/watch?v=Ve95Nh690l0</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=36347739</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=36347739</guid></item><item><title><![CDATA[New comment by yshrestha in "Ask HN: Who wants to be hired? (April 2023)"]]></title><description><![CDATA[
<p>Location: USA<p>Remote: Yes<p>Willing to relocate: No<p>Technologies: PyTorch, MONAI, DICOM, HL7, medical device regulations<p>Resume/CV: <a href="https://www.linkedin.com/in/yujanshrestha/" rel="nofollow">https://www.linkedin.com/in/yujanshrestha/</a><p>Email: yshrestha@innolitics.com<p>I am an expert in AI/ML for medical devices. I can help with engineering and regulatory concerns.</p>
]]></description><pubDate>Tue, 04 Apr 2023 05:12:53 +0000</pubDate><link>https://news.ycombinator.com/item?id=35435371</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=35435371</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=35435371</guid></item><item><title><![CDATA[New comment by yshrestha in "A.I. Versus the Law"]]></title><description><![CDATA[
<p>I thought this was an interesting analysis of the potential legal frameworks around generative AI.</p>
]]></description><pubDate>Tue, 31 Jan 2023 04:32:14 +0000</pubDate><link>https://news.ycombinator.com/item?id=34591156</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=34591156</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=34591156</guid></item><item><title><![CDATA[A.I. Versus the Law]]></title><description><![CDATA[
<p>Article URL: <a href="https://www.youtube.com/watch?v=G08hY8dSrUY">https://www.youtube.com/watch?v=G08hY8dSrUY</a></p>
<p>Comments URL: <a href="https://news.ycombinator.com/item?id=34591155">https://news.ycombinator.com/item?id=34591155</a></p>
<p>Points: 1</p>
<p># Comments: 1</p>
]]></description><pubDate>Tue, 31 Jan 2023 04:32:14 +0000</pubDate><link>https://www.youtube.com/watch?v=G08hY8dSrUY</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=34591155</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=34591155</guid></item><item><title><![CDATA[New comment by yshrestha in "Ask HN: How does a hobby programmer get hired?"]]></title><description><![CDATA[
<p>- Start a personal blog about software engineering principles<p>- Have some good code on GitHub<p>- Work for a startup, they are more likely to take chances on you<p>- Prefer working on-site if you can. Working remote is great once you have learned how to learn<p>Good luck with your search.</p>
]]></description><pubDate>Sun, 01 Jan 2023 21:56:05 +0000</pubDate><link>https://news.ycombinator.com/item?id=34211423</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=34211423</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=34211423</guid></item><item><title><![CDATA[New comment by yshrestha in "[dead]"]]></title><description><![CDATA[
<p>I have been using Notion AI for a couple of weeks and have found a couple of patterns / antipatterns that have worked well for my workflow.</p>
]]></description><pubDate>Sun, 01 Jan 2023 16:57:29 +0000</pubDate><link>https://news.ycombinator.com/item?id=34208030</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=34208030</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=34208030</guid></item><item><title><![CDATA[New comment by yshrestha in "Ask HN: What is your new year's resolution?"]]></title><description><![CDATA[
<p>A very simple way to improve work life balance</p>
]]></description><pubDate>Sat, 31 Dec 2022 16:28:30 +0000</pubDate><link>https://news.ycombinator.com/item?id=34197919</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=34197919</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=34197919</guid></item><item><title><![CDATA[New comment by yshrestha in "Ask HN: What is your new year's resolution?"]]></title><description><![CDATA[
<p>To learn how to stop saying "yes" to everything.</p>
]]></description><pubDate>Sat, 31 Dec 2022 06:02:28 +0000</pubDate><link>https://news.ycombinator.com/item?id=34194059</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=34194059</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=34194059</guid></item><item><title><![CDATA[Accelerating protein folding by an order of magnitude]]></title><description><![CDATA[
<p>Article URL: <a href="https://ai.facebook.com/blog/protein-folding-esmfold-metagenomics/">https://ai.facebook.com/blog/protein-folding-esmfold-metagenomics/</a></p>
<p>Comments URL: <a href="https://news.ycombinator.com/item?id=33431389">https://news.ycombinator.com/item?id=33431389</a></p>
<p>Points: 2</p>
<p># Comments: 0</p>
]]></description><pubDate>Wed, 02 Nov 2022 04:17:45 +0000</pubDate><link>https://ai.facebook.com/blog/protein-folding-esmfold-metagenomics/</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=33431389</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=33431389</guid></item><item><title><![CDATA[New comment by yshrestha in "AI language models are struggling to “get” math"]]></title><description><![CDATA[
<p>Exactly! Hey it gets the job done :)<p>Software is just a tall wedding cake of abstractions built on top of abstractions.</p>
]]></description><pubDate>Wed, 12 Oct 2022 16:28:47 +0000</pubDate><link>https://news.ycombinator.com/item?id=33179343</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=33179343</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=33179343</guid></item><item><title><![CDATA[New comment by yshrestha in "AI language models are struggling to “get” math"]]></title><description><![CDATA[
<p>Yeah! It is interesting to try and figure out "what" the model is actually learning. It is a valid thread of scientific inquiry.</p>
]]></description><pubDate>Wed, 12 Oct 2022 14:58:55 +0000</pubDate><link>https://news.ycombinator.com/item?id=33177934</link><dc:creator>yshrestha</dc:creator><comments>https://news.ycombinator.com/item?id=33177934</comments><guid isPermaLink="false">https://news.ycombinator.com/item?id=33177934</guid></item></channel></rss>